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  1. Content type: Research article

    Cognitive decline is a major concern in patients with migraine. Depression, anxiety, and/or poor sleep quality are well-known comorbidities of migraine, but available evidence on the subjective cognitive decli...

    Authors: Sun Hwa Lee, Yeonwook Kang and Soo-Jin Cho

    Citation: The Journal of Headache and Pain 2017 18:77

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  2. Content type: Research article

    OnabotulinumtoxinA has proven its efficacy in reducing the number of headache days in chronic migraine (CM) patients. The usual paradigm includes 31 pericranial injection sites with low dose (5 U) per site. Th...

    Authors: Danièle Ranoux, Gaelle Martiné, Gaëlle Espagne-Dubreuilh, Marlène Amilhaud-Bordier, François Caire and Laurent Magy

    Citation: The Journal of Headache and Pain 2017 18:75

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  3. Content type: Research article

    Migraine constitute a disorder characterized by recurrent headaches, and have a high prevalence, a high socio-economic burden and severe effects on quality of life. Our previous fMRI study demonstrated that so...

    Authors: Jilei Zhang, Yi-Lan Wu, Jingjing Su, Qian Yao, Mengxing Wang, Ge-Fei Li, Rong Zhao, Yan-Hui Shi, Ying Zhao, Qiting Zhang, Haifeng Lu, Shuai Xu, Zhaoxia Qin, Guo-Hong Cui, Jianqi Li, Jian-Ren Liu…

    Citation: The Journal of Headache and Pain 2017 18:74

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  4. Content type: Research article

    Several fMRI studies in migraine assessed resting state functional connectivity in different networks suggesting that this neurological condition was associated with brain functional alteration. The aim of pre...

    Authors: Viviana Lo Buono, Lilla Bonanno, Francesco Corallo, Laura Rosa Pisani, Riccardo Lo Presti, Rosario Grugno, Giuseppe Di Lorenzo, Placido Bramanti and Silvia Marino

    Citation: The Journal of Headache and Pain 2017 18:72

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  5. Content type: Research article

    Hemicrania continua (HC), paroxysmal hemicrania (PH) and short lasting neuralgiform headache attacks (SUNCT and SUNA) are rare syndromes with a difficult therapeutic approach. The aim of this review is to summ...

    Authors: Carlo Baraldi, Lanfranco Pellesi, Simona Guerzoni, Maria Michela Cainazzo and Luigi Alberto Pini

    Citation: The Journal of Headache and Pain 2017 18:71

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  6. Content type: Research article

    Neuroimaging data has implicated the temporal pole (TP) in migraine pathophysiology; the density and functional activity of the TP were reported to fluctuate in accordance with the migraine cycle. Yet, the exa...

    Authors: Francesca Cortese, Francesco Pierelli, Ilaria Bove, Cherubino Di Lorenzo, Maurizio Evangelista, Armando Perrotta, Mariano Serrao, Vincenzo Parisi and Gianluca Coppola

    Citation: The Journal of Headache and Pain 2017 18:70

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  7. Content type: Research article

    Mainly based on evidence of success in adults, various medications are commonly used to prevent pediatric migraines. Topiramate has been approved for migraine prevention in children as young as 12 years of age...

    Authors: Kai Le, Dafan Yu, Jiamin Wang, Abdoulaye Idriss Ali and Yijing Guo

    Citation: The Journal of Headache and Pain 2017 18:69

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  8. Content type: Erratum

    Authors: Stella Gagliardi, Gaetano Salvatore Grieco, Francesca Gualandi, Luisa Maria Caniatti, Elisabetta Groppo, Marialuisa Valente, Nappi Giuseppe, Marcella Neri and Cristina Cereda

    Citation: The Journal of Headache and Pain 2017 18:68

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    The original article was published in The Journal of Headache and Pain 2017 18:63

  9. Content type: Research article

    Individually both migraine and post-traumatic stress disorder (PTSD) prevalence estimates are higher among women. However, there is limited data on the association of migraine and PTSD in women during pregnancy.

    Authors: Lauren E. Friedman, Christina Aponte, Rigoberto Perez Hernandez, Juan Carlos Velez, Bizu Gelaye, Sixto E. Sánchez, Michelle A. Williams and B. Lee Peterlin

    Citation: The Journal of Headache and Pain 2017 18:67

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  10. Content type: Research article

    Chronic migraine is a complex clinical condition often undertreated. Onabotulinumtoxin A (OBT-A) was approved in Italy in 2013 for symptom relief in patients with chronic migraine who have failed, or do not to...

    Authors: Cristina Tassorelli, Marco Aguggia, Marina De Tommaso, Pierangelo Geppetti, Licia Grazzi, Luigi Alberto Pini, Paola Sarchielli, Gioacchino Tedeschi, Paolo Martelletti and Pietro Cortelli

    Citation: The Journal of Headache and Pain 2017 18:66

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  11. Content type: Research article

    No evidence is available on the risks of neurologically asymptomatic minimal traumatic intracranial hemorrhage (mTIH) in patients with traumatic brain injury (TBI) for post-traumatic headache (PTH). The purpos...

    Authors: Chang-Ki Hong, Yu Shik Shim, Sook Young Sim, Jin-Yang Joo, Min A Kwon, Yong Bae Kim and Joonho Chung

    Citation: The Journal of Headache and Pain 2017 18:64

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  12. Content type: Case report

    Sporadic Hemiplegic Migraine is a rare form of migraine headache. Mutations in three different genes, two ion-channel genes and one encoding an ATP exchanger, CACNA1A, ATP1A2 and SCN1A are all responsible for the...

    Authors: Stella Gagliardi, Gaetano Salvatore Grieco, Francesca Gualandi, Luisa Maria Caniatti, Elisabetta Groppo, Marialuisa Valente, Giuseppe Nappi, Marcella Neri and Cristina Cereda

    Citation: The Journal of Headache and Pain 2017 18:63

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    The Erratum to this article has been published in The Journal of Headache and Pain 2017 18:68

  13. Content type: Research article

    It is widely recognised that there are associations between headache, psychiatric comorbidity and attachment insecurity in both adults and children. The aims of this study were: 1) to compare perceived attachm...

    Authors: Riccardo Williams, Luigi Leone, Noemi Faedda, Giulia Natalucci, Benedetta Bellini, Elisa Salvi, Paola Verdecchia, Rita Cerutti, Marco Arruda and Vincenzo Guidetti

    Citation: The Journal of Headache and Pain 2017 18:62

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  14. Content type: Research article

    Calcitonin gene-related peptide (CGRP) is one of the most potent endogenous vasodilators identified to date. The present study elucidates the differential interaction of CGRP, its receptor and the effect of th...

    Authors: André Erdling, Majid Sheykhzade and Lars Edvinsson

    Citation: The Journal of Headache and Pain 2017 18:61

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  15. Content type: Research article

    Given that post-traumatic headache is one of the most prevalent and long-lasting post-concussion sequelae, causes significant morbidity, and might be associated with slower neurocognitive recovery, we sought t...

    Authors: Olivia Begasse de Dhaem, William B. Barr, Laura J. Balcer, Steven L. Galetta and Mia T. Minen

    Citation: The Journal of Headache and Pain 2017 18:60

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  16. Content type: Research article

    Central sensitization is an important epiphenomenon of the adult migraine, clinically expressed by allodynia, pericranial tenderness and comorbidity for fibromyalgia in a relevant number of patients. This stud...

    Authors: Marina de Tommaso, Vittorio Sciruicchio, Marianna Delussi, Eleonora Vecchio, Marvita Goffredo, Michele Simeone and Maria Grazia Foschino Barbaro

    Citation: The Journal of Headache and Pain 2017 18:59

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  17. Content type: Research article

    Headache disorders are the third-highest cause of disability worldwide, with migraine and medication-overuse headache (MOH) the major contributors. In Ethiopia we have shown these disorders to be highly preval...

    Authors: Mehila Zebenigus, Redda Tekle-Haimanot, Dawit K Worku, Hallie Thomas and Timothy J Steiner

    Citation: The Journal of Headache and Pain 2017 18:58

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  18. Content type: Research article

    Drug withdrawal still remains the key element in the treatment of Medication Overuse Headache (MOH), but there is no consensus about the withdrawal procedure. Still debated is the role of the steroid therapy. ...

    Authors: Sabina Cevoli, Giulia Giannini, Valentina Favoni, Rossana Terlizzi, Elisa Sancisi, Marianna Nicodemo, Stefano Zanigni, Maria Letizia Bacchi Reggiani, Giulia Pierangeli and Pietro Cortelli

    Citation: The Journal of Headache and Pain 2017 18:56

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  19. Content type: Research article

    Headache disorders are highly prevalent, and have a substantial and negative impact on health worldwide. They are largely treatable, but differences in structure, objectives, organization and delivery affect t...

    Authors: L. Pellesi, S. Benemei, V. Favoni, C. Lupi, E. Mampreso, A. Negro, M. Paolucci, T. J. Steiner, M. Ulivi, S. Cevoli and S. Guerzoni

    Citation: The Journal of Headache and Pain 2017 18:55

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  20. Content type: Research article

    The aim of this study was to evaluate the changes in the cognitive performance of migraine patients using a comprehensive series of cognitive/behavioral and electrophysiological tests.

    Authors: Lifang Huang, Hong juan Dong, Xi Wang, Yan Wang and Zheman Xiao

    Citation: The Journal of Headache and Pain 2017 18:54

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  21. Content type: Research article

    The Eurolight project assessed the impact of headache disorders in ten EU countries, using the same structured questionnaire but varying sampling methods. In Lithuania, sample selection employed methods in lin...

    Authors: Daiva Rastenytė, Dalia Mickevičienė, Lars Jacob Stovner, Hallie Thomas, Colette Andrée and Timothy J Steiner

    Citation: The Journal of Headache and Pain 2017 18:53

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  22. Content type: Research article

    Isometheptene is a sympathomimetic drug effective in acute migraine treatment. It is composed of two enantiomers with diverse pharmacological properties. This study investigated in pithed rats the cardiovascul...

    Authors: Alejandro Labastida-Ramírez, Eloísa Rubio-Beltrán, Oswaldo Hernández-Abreu, Bruce L. Daugherty, Antoinette MaassenVanDenBrink and Carlos M. Villalón

    Citation: The Journal of Headache and Pain 2017 18:52

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  23. Content type: Research article

    Hyperbaric oxygen (HBO) has the potential to relieve neuropathic pain. The purpose of this study was to determine whether the NO-cGMP-PKG signaling pathway is involved in the analgesic effects of early hyperba...

    Authors: Yuanyuan Ding, Peng Yao, Tao Hong, Zhenkai Han, Baisong Zhao and Weimin Chen

    Citation: The Journal of Headache and Pain 2017 18:51

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  24. Content type: Research article

    Sleep disorder and sleep complaints are common in subjects with migraine. Although the association between sleep disorders and migraine has been reported, the association between perceived insufficient sleep a...

    Authors: Jiyoung Kim, Soo-Jin Cho, Won-Joo Kim, Kwang Ik Yang, Chang-Ho Yun and Min Kyung Chu

    Citation: The Journal of Headache and Pain 2017 18:50

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  25. Content type: Research article

    Little is known about the long-term course of headache in patients with moderate-to-severe headache due to traumatic brain injury (TBI). We evaluated the course of headache in patients with moderate-to-severe...

    Authors: Chang-Ki Hong, Jin-Yang Joo, Yu Shik Shim, Sook Young Sim, Min A Kwon, Yong Bae Kim and Joonho Chung

    Citation: The Journal of Headache and Pain 2017 18:48

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  26. Content type: Research article

    Recent studies have shown a significant association between restless legs syndrome (RLS) and primary headache disorders. Nevertheless, information regarding the association between tension-type headache (TTH) ...

    Authors: Pil-Wook Chung, Soo-Jin Cho, Won-Joo Kim, Kwang Ik Yang, Chang-Ho Yun and Min Kyung Chu

    Citation: The Journal of Headache and Pain 2017 18:47

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  27. Content type: Research article

    The prevalence of migraine with co-existing tension-type headache and neck pain is high in the general population. However, there is very little literature on the characteristics of these combined conditions. ...

    Authors: Lotte Skytte Krøll, Catharina Sjödahl Hammarlund, Maria Lurenda Westergaard, Trine Nielsen, Louise Bönsdorff Sloth, Rigmor Højland Jensen and Gunvor Gard

    Citation: The Journal of Headache and Pain 2017 18:46

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  28. Content type: Research article

    Identification of subgroups of patients with different levels of sensitization and clinical features can help to identify groups at risk and the development of better therapeutic strategies. The aim of this st...

    Authors: César Fernández-de-las-Peñas, Elena Benito-González, María Palacios-Ceña, Kelun Wang, Matteo Castaldo and Lars Arendt-Nielsen

    Citation: The Journal of Headache and Pain 2017 18:43

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  29. Content type: Research article

    Migraine has been recognized as one of the leading causes of disability in the 2013 Global Burden of Disease Study and seriously affects the quality of patients’ life, current treatment options are not ideal. ...

    Authors: Min Hou, Haiyan Xing, Yongqing Cai, Bin Li, Xianfeng Wang, Pan Li, Xiaolin Hu and Jianhong Chen

    Citation: The Journal of Headache and Pain 2017 18:42

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  30. Content type: Research article

    Pain catastrophizing (PC) is associated with more severe and disabling migraine attacks. However, factors that moderate this relationship are unknown. Failure of inhibitory control (IC), or the ability to supp...

    Authors: Rachel Galioto, Kevin C. O’Leary, J. Graham Thomas, Kathryn Demos, Richard B. Lipton, John Gunstad, Jelena M. Pavlović, Julie Roth, Lucille Rathier and Dale S. Bond

    Citation: The Journal of Headache and Pain 2017 18:41

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  31. Content type: Research article

    Burning Mouth Syndrome (BMS) is a chronic pain condition characterized by persistent intraoral burning without related objective findings and unknown etiology that affects elderly females mostly. There is no s...

    Authors: Dimos D. Mitsikostas, Srdjan Ljubisavljevic and Christina I. Deligianni

    Citation: The Journal of Headache and Pain 2017 18:40

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  32. Content type: Research article

    Migraine is a debilitating neurological disorder where trigeminovascular activation plays a key role. We have previously reported that local application of Complete Freund’s Adjuvant (CFA) onto the dura mater ...

    Authors: M. Lukács, K. Warfvinge, J. Tajti, F. Fülöp, J. Toldi, L. Vécsei and L. Edvinsson

    Citation: The Journal of Headache and Pain 2017 18:39

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  33. Content type: Review article

    Despite their huge epidemiological impact, primary headaches, trigeminal neuralgia and other chronic pain conditions still receive suboptimal medical approach, even in developed countries. The limited efficacy...

    Authors: Giorgio Sandrini, Roberto De Icco, Cristina Tassorelli, Nicola Smania and Stefano Tamburin

    Citation: The Journal of Headache and Pain 2017 18:38

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  34. Content type: Research article

    Anxiety and mood disorders have been shown to be the most relevant psychiatric comorbidities associated with migraine, influencing its clinical course, treatment response, and clinical outcomes. Limited inform...

    Authors: Mario Fernando Prieto Peres, Juliane P. P. Mercante, Patricia R. Tobo, Helder Kamei and Marcelo Eduardo Bigal

    Citation: The Journal of Headache and Pain 2017 18:37

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  35. Content type: Research article

    The periaqueductal gray (PAG) dysfunction was recognized in migraine, and the altered dysfunction of PAG subregions were not totally detected up to now. The aim of this study is to investigate the altered func...

    Authors: Zhiye Chen, Xiaoyan Chen, Mengqi Liu, Shuangfeng Liu, Lin Ma and Shengyuan Yu

    Citation: The Journal of Headache and Pain 2017 18:36

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  36. Content type: Research article

    Some previous studies have postulated an association between migraine and excessive daytime sleepiness (EDS). This study evaluated the association of EDS with migraine and headache frequency in a general popul...

    Authors: Knut Stavem, Håvard Anton Kristiansen, Espen Saxhaug Kristoffersen, Kari Jorunn Kværner and Michael Bjørn Russell

    Citation: The Journal of Headache and Pain 2017 18:35

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  37. Content type: Research article

    Calcitonin gene-related peptide (CGRP) is widely distributed in nociceptive pathways in human peripheral and central nervous system and its receptors are also expressed in pain pathways. CGRP is involved in mi...

    Authors: Wendy Sophie Schou, Sait Ashina, Faisal Mohammad Amin, Peter J. Goadsby and Messoud Ashina

    Citation: The Journal of Headache and Pain 2017 18:34

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  38. Content type: Review article

    Migraine has long been known as a common complex disease caused by genetic and environmental factors. The pathophysiology and the specific genetic susceptibility are poorly understood. Common variants only exp...

    Authors: Rikke Dyhr Hansen, Anne Francke Christensen and Jes Olesen

    Citation: The Journal of Headache and Pain 2017 18:32

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  39. Content type: Research article

    DFN-02 is a novel intranasal spray formulation composed of sumatriptan 10 mg and a permeation-enhancing excipient comprised of 0.2% 1-O-n-Dodecyl-β-D-Maltopyranoside (DDM). This composition of DFN-02 allows su...

    Authors: Sagar Munjal, Elimor Brand-Schieber, Kent Allenby, Egilius L.H. Spierings, Roger K. Cady and Alan M. Rapoport

    Citation: The Journal of Headache and Pain 2017 18:31

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  40. Content type: Research article

    The aim of this study was to investigate cytokine levels in the masseter muscle, their response to experimental tooth-clenching and their relation to pain, fatigue and psychological distress in patients with t...

    Authors: S. Louca Jounger, N. Christidis, P. Svensson, T. List and M. Ernberg

    Citation: The Journal of Headache and Pain 2017 18:30

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  41. Content type: Research article

    The large geographical gaps in our knowledge of the prevalence and burden of headache disorders include almost all of Eastern Mediterranean Region (EMR). We report a nationwide population-based study in Pakist...

    Authors: A. A. Herekar, A. Ahmad, U. L. Uqaili, B. Ahmed, J. Effendi, S. Z. Alvi, M. A. Shahab, U. Javed, A. D. Herekar, Rafiq Khanani and T. J. Steiner

    Citation: The Journal of Headache and Pain 2017 18:28

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