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  1. Data are limited regarding the combined impact of headache frequency and failure of preventive medication (efficacy and/or tolerability) on the humanistic/economic burden of migraine.

    Authors: Dawn C. Buse, Patricia Pozo-Rosich, Laure Dupont-Benjamin, Bridget L. Balkaran, Lulu Lee, Adam Jauregui, Pranav Gandhi, Mousam Parikh and Uwe Reuter
    Citation: The Journal of Headache and Pain 2023 24:115
  2. Headache is one of the most common neurological symptoms. Many previous studies have indicated a relationship between primary headaches and alcohol. Drinking has been associated with increased risk of tension-...

    Authors: Bartłomiej Błaszczyk, Marcin Straburzyński, Mieszko Więckiewicz, Sławomir Budrewicz, Piotr Niemiec, Martyna Staszkiewicz and Marta Waliszewska-Prosół
    Citation: The Journal of Headache and Pain 2023 24:116
  3. Cluster headache (CH) is a primary headache disorder which is characterized by circadian timing of headache attacks, usually at nighttime, in around two thirds of patients. Patients with CH often report sleep ...

    Authors: Caroline Ran, Felicia Jennysdotter Olofsgård, Anna Steinberg, Christina Sjöstrand, Elisabet Waldenlind, Anna Dahlgren and Andrea Carmine Belin
    Citation: The Journal of Headache and Pain 2023 24:114
  4. Primary headache disorders are a group of highly prevalent and disabling neurological diseases that mainly consist of migraine and tension-type headache (TTH). A previous study showed that the burden of headac...

    Authors: Rongguang Ge, Jie Chang and Yongjun Cao
    Citation: The Journal of Headache and Pain 2023 24:110
  5. While previous genome-wide association studies (GWAS) have identified multiple risk variants for migraine, there is a lack of evidence about how these variants contribute to the development of migraine. We emp...

    Authors: Shuang-jie Li, Jing-jing Shi, Cheng-yuan Mao, Chan Zhang, Ya-fang Xu, Yu Fan, Zheng-wei Hu, Wen-kai Yu, Xiao-yan Hao, Meng-jie Li, Jia-di Li, Dong-rui Ma, Meng-nan Guo, Chun-yan Zuo, Yuan-yuan Liang, Yu-ming Xu…
    Citation: The Journal of Headache and Pain 2023 24:111
  6. It is unknown whether new daily persistent headache (NDPH) is a single disorder or heterogenous group of disorders, and whether it is a unique disorder from chronic migraine and chronic tension-type headache. ...

    Authors: Sanjay Cheema, Anker Stubberud, Khadija Rantell, Parashkev Nachev, Erling Tronvik and Manjit Matharu
    Citation: The Journal of Headache and Pain 2023 24:109
  7. Calcitonin gene-related peptide (CGRP) is involved in migraine pathophysiology and blood pressure regulation. Although clinical trials have established the cardio-cerebrovascular safety profile of anti-CGRP tr...

    Authors: Kaicheng Wang, Brenda T. Fenton, Vinh X. Dao, Alexander B. Guirguis, Sarah E. Anthony, Melissa Skanderson and Jason J. Sico
    Citation: The Journal of Headache and Pain 2023 24:108
  8. Authors: Adrian Scutelnic, Hristina Drangova, Antonia Klein, Nedelina Slavova, Morin Beyeler, Julian Lippert, Norbert Silimon, Thomas R. Meinel, Marcel Arnold, Urs Fischer, Franz Riederer, Heinrich P. Mattle, Simon Jung and Christoph J. Schankin
    Citation: The Journal of Headache and Pain 2023 24:107

    The original article was published in The Journal of Headache and Pain 2023 24:100

  9. There is increasing evidence from human and animal studies that cortical spreading depression (CSD) is the neurophysiological correlate of migraine aura and a trigger of migraine pain mechanisms. The mechanism...

    Authors: Marina Vitale, Angelita Tottene, Maral Zarin Zadeh, KC Brennan and Daniela Pietrobon
    Citation: The Journal of Headache and Pain 2023 24:105

    The Correction to this article has been published in The Journal of Headache and Pain 2023 24:171

  10. Migraine is a cyclic, neurosensory disorder characterized by recurrent headaches and altered sensory processing. The latter is manifested in hypersensitivity to visual stimuli, measured with questionnaires and...

    Authors: Angela Marti-Marca, Adrià Vilà-Balló, Xim Cerda-Company, Nara Ikumi, Marta Torres-Ferrus, Edoardo Caronna, Victor J. Gallardo, Alicia Alpuente, Mireia Torralba Cuello, Salvador Soto-Faraco and Patricia Pozo-Rosich
    Citation: The Journal of Headache and Pain 2023 24:104
  11. The phase 3 randomized PERSIST study demonstrated the efficacy and tolerability of galcanezumab, a humanized anti-calcitonin gene-related peptide (CGRP) monoclonal antibody for prevention of episodic migraines...

    Authors: Jiying Zhou, Lianmei Zhong, Debashish Chowdhury, Kirill Skorobogatykh, Guogang Luo, Xiaosu Yang, Mingjie Zhang, Lingli Sun, Hui Liu, Chenxi Qian and Shengyuan Yu
    Citation: The Journal of Headache and Pain 2023 24:103
  12. Individuals using onabotulinumtoxinA as a preventive migraine treatment often use acute treatments for breakthrough attacks. Data on real-world effectiveness of the small-molecule calcitonin gene–related pepti...

    Authors: Aubrey Manack Adams, Susan Hutchinson, Ella Engstrom, Nicolai D. Ayasse, Daniel Serrano, Linda Davis, Katherine Sommer, Janette Contreras-De Lama and Richard B. Lipton
    Citation: The Journal of Headache and Pain 2023 24:102
  13. To date, real-world evidence on persistence to anti-calcitonin gene-related peptide (anti-CGRP) monoclonal antibodies (mAbs) or onabotulinumtoxinA have excluded eptinezumab. This retrospective cohort study was...

    Authors: Larry Charleston IV, Brian Talon, Christine Sullivan, Carlton Anderson, Steven Kymes, Stephane A. Regnier, Seema Soni-Brahmbhatt and Stephanie J. Nahas
    Citation: The Journal of Headache and Pain 2023 24:101
  14. Given the similar presentation of migraine aura and acute ischemic stroke, advancing patient age might change the characteristics of migraine with aura (MA) and be clinically important. Clinical data, however,...

    Authors: Adrian Scutelnic, Hristina Drangova, Antonia Klein, Nedelina Slavova, Morin Beyeler, Julian Lippert, Norbert Silimon, Thomas R. Meinel, Marcel Arnold, Urs Fischer, Franz Riederer, Heinrich P. Mattle, Simon Jung and Christoph J. Schankin
    Citation: The Journal of Headache and Pain 2023 24:100

    The Correction to this article has been published in The Journal of Headache and Pain 2023 24:107

  15. The monoclonal antibodies (mAbs) blocking the calcitonin-gene related peptide (CGRP) pathway, collectively called here “anti-CGRP/rec mAbs”, have dramatically improved preventive migraine treatment. Although t...

    Authors: Jean Schoenen, Annelies Van Dycke, Jan Versijpt and Koen Paemeleire
    Citation: The Journal of Headache and Pain 2023 24:99
  16. Whether migraine is related to the risk of cardiovascular diseases (CVDs) remains unclear. Therefore, we conducted a longitudinal follow-up study to address the association between migraine and the development...

    Authors: Mi Jung Kwon, Hyo Geun Choi, Yoo Hwan Kim, Joo-Hee Kim, Hyun Taek Rim, Heui Seung Lee, Jae Keun Oh, In Bok Chang, Joon Ho Song and Ji Hee Kim
    Citation: The Journal of Headache and Pain 2023 24:98
  17. In idiopathic intracranial hypertension (IIH), certain MRI features are promising diagnostic markers, but whether these have prognostic value is currently unknown.

    Authors: Gabriel Bsteh, Wolfgang Marik, Nik Krajnc, Stefan Macher, Christoph Mitsch, Philip Pruckner, Klaus Novak, Christian Wöber and Berthold Pemp
    Citation: The Journal of Headache and Pain 2023 24:97
  18. The evidence supporting the efficacy of dietary preventive therapy in migraine is rising, particularly regarding the ketogenic diet. However, less evidence exists for the Low-Glycemic Index Diet and the 2:1 KD...

    Authors: Yan Tereshko, Simone Dal Bello, Cherubino Di Lorenzo, Sara Pez, Alice Pittino, Roberto Sartor, Francesca Filippi, Christian Lettieri, Enrico Belgrado, Riccardo Garbo, Giovanni Merlino, Gian Luigi Gigli and Mariarosaria Valente
    Citation: The Journal of Headache and Pain 2023 24:95
  19. Cortical spreading depolarization (CSD), the neurophysiological correlate of the migraine aura, can activate trigeminal pain pathways, but the neurobiological mechanisms and behavioural consequences remain unc...

    Authors: Anisa Dehghani, Maarten Schenke, Sandra H. van Heiningen, Hulya Karatas, Else A. Tolner and Arn M. J. M. van den Maagdenberg
    Citation: The Journal of Headache and Pain 2023 24:96
  20. Migraine headache attacks and accompanying sensory augmentation can be induced by several agents including levcromakalim (LVC), that is also capable of provoking aura-like symptoms in migraineurs. We investiga...

    Authors: Berkay Alpay, Bariscan Cimen, Elif Akaydin, Hayrunnisa Bolay and Yildirim Sara
    Citation: The Journal of Headache and Pain 2023 24:93
  21. Tension-type headache (TTH) and migraine are two common primary headaches distinguished by clinical characteristics according to the 3rd edition of the International Classification of Headache Disorders. Migraine...

    Authors: Dilara Onan, Samaira Younis, William David Wellsgatnik, Fatemeh Farham, Saulius Andruškevičius, Ana Abashidze, Asel Jusupova, Yuriy Romanenko, Oxana Grosu, Meerimgul Zamirbekovna Moldokulova, Ulkar Mursalova, Saida Saidkhodjaeva, Paolo Martelletti and Sait Ashina
    Citation: The Journal of Headache and Pain 2023 24:92
  22. Migraine is more prevalent in females, raising the possibility that sex and gonadal hormones modulate migraine. We recently demonstrated that minimally invasive optogenetic spreading depolarization (opto-SD) e...

    Authors: Andrea M. Harriott, Angel Waruinge, Viola Appiah-Danquah, Leah Berhanu, Andreia Morais and Cenk Ayata
    Citation: The Journal of Headache and Pain 2023 24:85
  23. Trigeminal neuralgia (TN) is a debilitating pain disorder that still lacks an ideal treatment option. Pulsed radiofrequency (PRF), especially with high output voltage, is a novel and minimally invasive techniq...

    Authors: Yitong Jia, Hao Cheng, Niti Shrestha, Hao Ren, Chunmei Zhao, Kunpeng Feng and Fang Luo
    Citation: The Journal of Headache and Pain 2023 24:91
  24. In idiopathic intracranial hypertension (IIH), sustained weight loss is the main pillar in modifying disease course, whereby glucagon-like peptide-1 receptor agonists (GLP-1-RAs) could present an attractive tr...

    Authors: Nik Krajnc, Bianca Itariu, Stefan Macher, Wolfgang Marik, Jürgen Harreiter, Martin Michl, Klaus Novak, Christian Wöber, Berthold Pemp and Gabriel Bsteh
    Citation: The Journal of Headache and Pain 2023 24:89
  25. Insights into the burden, needs and treatment of migraine from internet-based surveys in diverse real-world migraine populations are needed, especially at a time when novel preventive migraine medications are ...

    Authors: Julio Pascual, Tommaso Panni, Grazia Dell’Agnello, Saygin Gonderten, Diego Novick and Stefan Evers
    Citation: The Journal of Headache and Pain 2023 24:88

    The Correction to this article has been published in The Journal of Headache and Pain 2023 24:142

  26. The Notch gene, a highly evolutionarily conserved gene, was discovered approximately 110 years ago and has been found to play a crucial role in the development of multicellular organisms. Notch receptors and t...

    Authors: Yan Zhang, Tingting Wang, Sanlan Wu, Li Tang, Jia Wang, Jinghan Yang, Shanglong Yao and Yan Zhang
    Citation: The Journal of Headache and Pain 2023 24:87
  27. Mindfulness gained considerable attention for migraine management, but RCTs are lacking. We aimed to assess the efficacy of a six-sessions mindfulness-based treatment added to treatment as usual (TaU) in patie...

    Authors: Licia Grazzi, Domenico D’Amico, Erika Guastafierro, Greta Demichelis, Alessandra Erbetta, Davide Fedeli, Anna Nigri, Emilio Ciusani, Corso Barbara and Alberto Raggi
    Citation: The Journal of Headache and Pain 2023 24:86
  28. Tension-type headache (TTH) is the most prevalent primary headache disorder. Neck pain is commonly associated with primary headaches and the trigemino-cervical complex (TCC) refers to the convergence of trigem...

    Authors: Nico Sollmann, Paul Schandelmaier, Dominik Weidlich, Jonathan Stelter, Gabby B. Joseph, Corinna Börner, Severin Schramm, Meinrad Beer, Claus Zimmer, Mirjam N. Landgraf, Florian Heinen, Dimitrios C. Karampinos, Thomas Baum and Michaela V. Bonfert
    Citation: The Journal of Headache and Pain 2023 24:84
  29. Migraine is a very common headache disorder on the population level, characterized by symptomatic attacks (activity). For many people with migraine, the migraine symptoms intermittently or permanently cease du...

    Authors: Marco Piccininni, Ralph Brinks, Jessica L. Rohmann and Tobias Kurth
    Citation: The Journal of Headache and Pain 2023 24:83
  30. The close relationship between pain and mental health problems is well-known, and psychological intervention can provide an effective alternative to medication-based pain relief. However, previous studies on t...

    Authors: Chongjie Yao, Yuchen Zhang, Ping Lu, Bin Xiao, Pingping Sun, Jiming Tao, Yanbin Cheng, Lingjun Kong, Dongsheng Xu and Min Fang
    Citation: The Journal of Headache and Pain 2023 24:82
  31. Menstrual migraine is a subtype of migraine disease that is typically more disabling, longer-lasting, and more challenging to treat. The purpose of this network meta-analysis (NMA) is to compare the relative e...

    Authors: Han Zhang, Jian-Zhi Qi and Zhi-Hua Zhang
    Citation: The Journal of Headache and Pain 2023 24:81
  32. New daily persistent headache (NDPH) is a rare primary headache disorder characterized by daily and persistent sudden onset headaches. The pathogenesis of NDPH remains unclear, and there are few white matter i...

    Authors: Yanliang Mei, Wei Wang, Dong Qiu, Ziyu Yuan, Xiaoyan Bai, Hefei Tang, Peng Zhang, Xue Zhang, Yaqing Zhang, Xueying Yu, Binbin Sui and Yonggang Wang
    Citation: The Journal of Headache and Pain 2023 24:80
  33. The majority of epidemiological studies on migraine have been conducted in a specific country or region, and there is a lack of globally comparable data. We aim to report the latest information on global migra...

    Authors: Luying Fan, Yuhang Wu, Jiehua Wei, Fan Xia, Yufeng Cai, Senmao Zhang, Junxiang Miao, Yunzhe Zhou, Chu Liu, Wei Yan, Dan Liu, Lizhang Chen and Tingting Wang
    Citation: The Journal of Headache and Pain 2023 24:79
  34. Prior clinical studies suggest a shared mechanism between vestibular symptoms and migraine headache. However, the specific neuroanatomical substrate connecting vestibular symptoms with migraine remains to be l...

    Authors: Yun Zhang, Yixin Zhang, Yanyun Wang, Xiaoyan Zhang, Guangcheng Qin, Dunke Zhang, Lixue Chen and Jiying Zhou
    Citation: The Journal of Headache and Pain 2023 24:77
  35. Migraine is a common and complex neurological disease potentially caused by a polygenic interaction of multiple gene variants. Many genes associated with migraine are involved in pathways controlling the synap...

    Authors: Daniela Felício, Andreia Dias, Sandra Martins, Estefânia Carvalho, Alexandra M. Lopes, Nádia Pinto, Carolina Lemos, Mariana Santos and Miguel Alves-Ferreira
    Citation: The Journal of Headache and Pain 2023 24:78
  36. Migraine is a disabling and chronic neurovascular headache disorder. Trigeminal vascular activation and release of calcitonin gene-related peptide (CGRP) play a pivotal role in the pathogenesis of migraine. Th...

    Authors: Linda Al-Hassany, Deirdre M. Boucherie, Hannah Creeney, Ruben W. A. van Drie, Fatemeh Farham, Silvia Favaretto, Cédric Gollion, Lou Grangeon, Hannah Lyons, Karol Marschollek, Dilara Onan, Umberto Pensato, Emily Stanyer, Marta Waliszewska-Prosół, Wietse Wiels, Hui Zhou Chen…
    Citation: The Journal of Headache and Pain 2023 24:76
  37. Real-world data are accumulating on the effectiveness, tolerability and safety of anti-calcitonin gene-related peptide pathway monoclonal antibodies for the preventive treatment of migraine. We performed a sys...

    Authors: Nicolas Vandenbussche, Karolina Pisarek and Koen Paemeleire
    Citation: The Journal of Headache and Pain 2023 24:75
  38. Authors: Nadja Bredo Rasmussen, Christina Deligianni, Casper Emil Christensen, William Kristian Karlsson, Haidar Muhsen Al-Khazali, Tom Van de Casteele, Charlotte Granhall, Faisal Mohammad Amin and Messoud Ashina
    Citation: The Journal of Headache and Pain 2023 24:74

    The original article was published in The Journal of Headache and Pain 2023 24:60

  39. Advanced neuroimaging techniques have extensively contributed to elucidate the complex mechanisms underpinning the pathophysiology of migraine, a neurovascular disorder characterized by episodes of headache as...

    Authors: Antonio Russo, Marcello Silvestro, Alessandro Tessitore, Ilaria Orologio, Alessandro Pasquale De Rosa, Rosa De Micco, Gioacchino Tedeschi, Fabrizio Esposito and Mario Cirillo
    Citation: The Journal of Headache and Pain 2023 24:71
  40. Repeat mild traumatic brain injuries (RmTBI) result in substantial burden to the public health system given their association with chronic post-injury pathologies, such as chronic pain and post-traumatic heada...

    Authors: Jennaya Christensen, Naomi MacPherson, Crystal Li, Glenn R. Yamakawa and Richelle Mychasiuk
    Citation: The Journal of Headache and Pain 2023 24:72
  41. Erenumab has demonstrated effectiveness for prevention of migraine attacks, but the treatment is costly, and a considerable proportion of patients do not respond to it. The Registry for Migraine study (REFORM)...

    Authors: William Kristian Karlsson, Håkan Ashina, Christopher Kjær Cullum, Rune Häckert Christensen, Haidar Muhsen Al-Khazali, Faisal Mohammad Amin and Messoud Ashina
    Citation: The Journal of Headache and Pain 2023 24:70
  42. Migraine is a debilitating disorder, and while the introduction of monoclonal antibodies (mAbs) has led to efficacious and tolerable responses, a substantial number of patients are so-called “non-responders”. ...

    Authors: Linda Al-Hassany, Nazia Karsan, Christian Lampl, Peter J. Goadsby and Antoinette MaassenVanDenBrink
    Citation: The Journal of Headache and Pain 2023 24:69
  43. The main objective of this clinical practice guideline is to provide a series of recommendations for healthcare and exercise professionals, such as neurologists, physical therapists, and exercise physiologists...

    Authors: Roy La Touche, José Fierro-Marrero, Irene Sánchez-Ruíz, Borja Rodríguez de Rivera-Romero, Carlos Donato Cabrera-López, Sergio Lerma-Lara, Néstor Requejo-Salinas, Francisco de Asís-Fernández, Ignacio Elizagaray-García, Josué Fernández-Carnero, Luís Matesanz-García, Joaquín Pardo-Montero, Alba Paris-Alemany and Álvaro Reina-Varona
    Citation: The Journal of Headache and Pain 2023 24:68
  44. Migraine is a disabling neurological disorder whose diagnosis is based on clinical criteria. A shortcoming of these criteria is that they do not fully capture the underlying neurobiological factors and sex-spe...

    Authors: F. C. van Welie, L. A. Kreft, J. M. A. Huisman and G. M. Terwindt
    Citation: The Journal of Headache and Pain 2023 24:64