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  1. Content type: Review article

    Migraine is a major public health problem afflicting approximately 10% of the general population and is a leading cause of disability worldwide, yet our understanding of the basis mechanisms of migraine remain...

    Authors: Jakob Møller Hansen and Andrew Charles

    Citation: The Journal of Headache and Pain 2019 20:96

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  2. Content type: Review article

    Migraine is a complex brain disorder and initiating events for acute attacks still remain unclear. It seems difficult to explain the development of migraine headache with one mechanism and/or a single anatomic...

    Authors: Hayrunnisa Bolay, Doga Vuralli and Peter J. Goadsby

    Citation: The Journal of Headache and Pain 2019 20:94

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  3. Content type: Research article

    Increasing evidence has suggested that the cerebellum is associated with pain and migraine. In addition, the descending pain system of the brainstem is the major site of trigeminal pain processing and modulati...

    Authors: Zhaoxia Qin, Xin-Wei He, Jilei Zhang, Shuai Xu, Ge-Fei Li, Jingjing Su, Yan-Hui Shi, Shiyu Ban, Yue Hu, Yi-Sheng Liu, Mei-Ting Zhuang, Rong Zhao, Xiao-Lei Shen, Jianqi Li, Jian-Ren Liu and Xiaoxia Du

    Citation: The Journal of Headache and Pain 2019 20:93

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  4. Content type: Review article

    Chronic migraine is a disabling condition that is currently underdiagnosed and undertreated. In this narrative review, we discuss the future of chronic migraine management in relation to recent progress in evi...

    Authors: Elio Clemente Agostoni, Piero Barbanti, Paolo Calabresi, Bruno Colombo, Pietro Cortelli, Fabio Frediani, Pietrangelo Geppetti, Licia Grazzi, Massimo Leone, Paolo Martelletti, Luigi Alberto Pini, Maria Pia Prudenzano, Paola Sarchielli, Gioacchino Tedeschi and Antonio Russo

    Citation: The Journal of Headache and Pain 2019 20:92

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  5. Content type: Review article

    Migraine is a common debilitating condition whose main attributes are severe recurrent headaches with accompanying sensitivity to light and sound, nausea and vomiting. Migraine-related pain is a major cause of...

    Authors: Andrea M. Harriott, Lauren C. Strother, Marta Vila-Pueyo and Philip R. Holland

    Citation: The Journal of Headache and Pain 2019 20:91

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  6. Content type: Research article

    In addition to the increased risk for cardiovascular (CV) disease and CV events associated with migraine, patients with migraine can also present with a number of CV risk factors (CVRFs). Existing treatment op...

    Authors: Robert E. Shapiro, Helen M. Hochstetler, Ellen B. Dennehy, Rashna Khanna, Erin Gautier Doty, Paul H. Berg and Amaal J. Starling

    Citation: The Journal of Headache and Pain 2019 20:90

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  7. Content type: Research article

    Migraine diagnosis is based on clinical aspects and is dependent on the experience of the attending physician. This study aimed to describe the patients journey profile until they start their experience in a t...

    Authors: Mario Fernando Prieto Peres, Diego Belandrino Swerts, Arão Belitardo de Oliveira and Raimundo Pereira Silva-Neto

    Citation: The Journal of Headache and Pain 2019 20:88

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  8. Content type: Research article

    Migraine is a debilitating neurological disorder involving abnormal trigeminovascular activation and sensitization. However, the underlying cellular and molecular mechanisms remain unclear.

    Authors: Junping Cao, Yuan Zhang, Lei Wu, Lidong Shan, Yufang Sun, Xinghong Jiang and Jin Tao

    Citation: The Journal of Headache and Pain 2019 20:87

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  9. Content type: Research article

    Migraine is a common and severely disabling neurological disorder affecting millions of patients in Europe. Despite the availability of evidence-based national and international guidelines, the management of m...

    Authors: Christian Ziegeler, Greta Brauns, Tim P. Jürgens and Arne May

    Citation: The Journal of Headache and Pain 2019 20:86

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  10. Content type: Research article

    Even though migraine and other primary headache disorders are common and debilitating, major health surveys in Brazil have not included them. We repair this omission by combining data on non-communicable disea...

    Authors: Mario Fernando Prieto Peres, Luiz Paulo Queiroz, Pedro Sampaio Rocha-Filho, Elder Machado Sarmento, Zaza Katsarava and Timothy J. Steiner

    Citation: The Journal of Headache and Pain 2019 20:85

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  11. Content type: Research article

    To study the efficacy and safety of lasmiditan for acute treatment of migraine in patients using migraine preventive medications.

    Authors: Li Shen Loo, Jessica Ailani, Jack Schim, Simin Baygani, Hans-Peter Hundemer, Martha Port and John H. Krege

    Citation: The Journal of Headache and Pain 2019 20:84

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  12. Content type: Research article

    There is a significant unmet need for new, effective and well tolerated acute migraine treatments. A recent study has demonstrated that a novel remote electrical neuromodulation (REN) treatment provides superi...

    Authors: Alan M. Rapoport, Jo H. Bonner, Tamar Lin, Dagan Harris, Yaron Gruper, Alon Ironi and Robert P. Cowan

    Citation: The Journal of Headache and Pain 2019 20:83

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  13. Content type: Research article

    OnabotulinumtoxinA (BOTOX®, Allergan plc, Dublin, Ireland) is approved for the preventive treatment of headaches in adult patients with chronic migraine (CM) in Australia by the country’s reimbursement mechani...

    Authors: Catherine Stark, Richard Stark, Nicole Limberg, Julian Rodrigues, Dennis Cordato, Raymond Schwartz and Robert Jukic

    Citation: The Journal of Headache and Pain 2019 20:81

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  14. Content type: Review article

    Mouse models of rare monogenic forms of migraine provide a unique experimental system to study the cellular and circuit mechanisms of the primary brain dysfunctions causing a migraine disorder. Here, we discus...

    Authors: Daniela Pietrobon and K. C. Brennan

    Citation: The Journal of Headache and Pain 2019 20:79

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  15. Content type: Research article

    Several studies have investigated white matter with diffusion tensor imaging (DTI) in those suffering from headache, but so far only in clinic based samples and with conflicting results.

    Authors: Andreas Kattem Husøy, Live Eikenes, Asta K. Håberg, Knut Hagen and Lars Jacob Stovner

    Citation: The Journal of Headache and Pain 2019 20:78

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  16. Content type: Research article

    The migraine brain seems to undergo cyclic fluctuations of sensory processing. For instance, during the preictal phase, migraineurs experience symptoms and signs of altered pain perception as well as other wel...

    Authors: Martin Syvertsen Mykland, Marte Helene Bjørk, Marit Stjern, Petter Moe Omland, Martin Uglem and Trond Sand

    Citation: The Journal of Headache and Pain 2019 20:77

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  17. Content type: Research article

    Patients with high-frequency episodic migraine (HFEM) have a greater disease burden than those with low-frequency episodic migraine (LFEM). Acute treatment overuse increases the risk of migraine chronification...

    Authors: Stephen D. Silberstein, Virginia L. Stauffer, Katie A. Day, Sarah Lipsius and Maria-Carmen Wilson

    Citation: The Journal of Headache and Pain 2019 20:75

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  18. Content type: Research article

    Although migraine is a disabling neurological condition that causes important disability, it remains an area of underdiagnosis and undertreatment worldwide. The aim of this study was to depict the burden of th...

    Authors: Carlo Piccinni, Sabina Cevoli, Giulia Ronconi, Letizia Dondi, Silvia Calabria, Antonella Pedrini, Immacolata Esposito, Valentina Favoni, Giulia Pierangeli, Pietro Cortelli and Nello Martini

    Citation: The Journal of Headache and Pain 2019 20:74

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  19. Content type: Research article

    To assess the quality of the therapeutic approach in Specialized Headache Units in Spain.

    Authors: Patricia Pozo-Rosich, Alba Martínez-García, Julio Pascual, Emilio Ignacio, Ángel L. Guerrero-Peral, José Balseiro-Gómez, Jesús Porta-Etessam, Germán Latorre-González, Almudena Layos-Romero, César Lucas and José J. Mira

    Citation: The Journal of Headache and Pain 2019 20:73

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  20. Content type: Review article

    Migraine is a complex neurovascular disorder with a strong genetic component. There are rare monogenic forms of migraine, as well as more common polygenic forms; research into the genes involved in both types ...

    Authors: Heidi G. Sutherland, Cassie L. Albury and Lyn R. Griffiths

    Citation: The Journal of Headache and Pain 2019 20:72

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  21. Content type: Research article

    Questionnaire-based headache diagnoses should be validated against diagnoses made by the gold standard, which is personal interview by a headache expert. The diagnostic algorithm with the best diagnostic accur...

    Authors: Knut Hagen, Anders Nikolai Åsberg, Benjamin L. Uhlig, Erling Tronvik, Eiliv Brenner and Trond Sand

    Citation: The Journal of Headache and Pain 2019 20:70

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  22. Content type: Research article

    In Japan, detailed information on the characteristics, disease burden, and treatment patterns of people living with migraine is limited. The aim of this study was to compare clinical characteristics, disease b...

    Authors: Kaname Ueda, Wenyu Ye, Louise Lombard, Atsushi Kuga, Yongin Kim, Sarah Cotton, James Jackson and Tamas Treuer

    Citation: The Journal of Headache and Pain 2019 20:68

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  23. Content type: Research article

    Monoclonal antibodies (mAbs) targeting the CGRP pathway are safe and efficacious therapies for the prevention of migraine. In this study we assessed the effects of discontinuation of preventive erenumab and ga...

    Authors: Bianca Raffaelli, Valeria Mussetto, Heike Israel, Lars Neeb and Uwe Reuter

    Citation: The Journal of Headache and Pain 2019 20:66

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  24. Content type: Research article

    Migraine is a disabling, chronic neurological disease leading to severe headache episodes affecting 13.2% of the Swedish population. Migraine leads to an extensive socio-economic burden in terms of healthcare ...

    Authors: Frida Hjalte, Sara Olofsson, Ulf Persson and Mattias Linde

    Citation: The Journal of Headache and Pain 2019 20:65

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  25. Content type: Review article

    Migraine aura (MA) is a common and disabling neurological condition, characterized by transient visual, and less frequently sensory and dysphasic aura disturbances.

    Authors: Michele Viana, Erling Andreas Tronvik, Thien Phu Do, Chiara Zecca and Anders Hougaard

    Citation: The Journal of Headache and Pain 2019 20:64

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  26. Content type: Correction

    After publication of the original article [1], the authors have notified us that an updated version of Figures 1, 2 and 3 should have been published. The incorrect and revised figures can be found below.

    Authors: Casper Emil Christensen, Samaira Younis, Ulrich Lindberg, Vincent Oltman Boer, Patrick de Koning, Esben Thade Petersen, Olaf Bjarne Paulson, Henrik Bo Wiberg Larsson, Faisal Mohammad Amin and Messoud Ashina

    Citation: The Journal of Headache and Pain 2019 20:62

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    The original article was published in The Journal of Headache and Pain 2019 20:48

  27. Content type: Research article

    Perturbation of neuronal excitability contributes to migraine. Neurosteroids modulate the activity of γ-aminobutyric acid A and N-methyl-d-aspartate receptors, and might be involved in the pathogenesis of migr...

    Authors: Angela Koverech, Claudia Cicione, Luana Lionetto, Marta Maestri, Francesco Passariello, Elisabetta Sabbatini, Matilde Capi, Cristiano Maria De Marco, Martina Guglielmetti, Andrea Negro, Luisa Di Menna, Maurizio Simmaco, Ferdinando Nicoletti and Paolo Martelletti

    Citation: The Journal of Headache and Pain 2019 20:61

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  28. Content type: Research article

    Elevation of intracranial pressure in idiopathic intracranial hypertension induces an edema of the prelaminar section of the optic nerve (papilledema). Beside the commonly observed optic nerve sheath distentio...

    Authors: Jan Hoffmann, Katharina Maria Kreutz, Christoph Csapó-Schmidt, Nils Becker, Hagen Kunte, Lucius Samo Fekonja, Anas Jadan and Edzard Wiener

    Citation: The Journal of Headache and Pain 2019 20:59

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  29. Content type: Correction

    Abstract

    Authors: Simona Sacco, Lars Bendtsen, Messoud Ashina, Uwe Reuter, Gisela Terwindt, Dimos-Dimitrios Mitsikostas and Paolo Martelletti

    Citation: The Journal of Headache and Pain 2019 20:58

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    The original article was published in The Journal of Headache and Pain 2019 20:6

    The Letter to the Editor to this article has been published in The Journal of Headache and Pain 2019 20:67

    The Letter to the Editor to this article has been published in The Journal of Headache and Pain 2019 20:22

  30. Content type: Consensus article

    The Aids to Management are a product of the Global Campaign against Headache, a worldwide programme of action conducted in official relations with the World Health Organization. Developed in partnership with the ...

    Authors: T. J. Steiner, R. Jensen, Z. Katsarava, M. Linde, E. A. MacGregor, V. Osipova, K. Paemeleire, J. Olesen, M. Peters and P. Martelletti

    Citation: The Journal of Headache and Pain 2019 20:57

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  31. Content type: Review article

    Migraine is the most disabling and expensive chronic disorders, the etiology of which is still not fully known. The neuronal systems, (glutammatergic, dopaminergic, serotoninergic and GABA-ergic) whose functio...

    Authors: Leda Marina Pomes, Martina Guglielmetti, Enrico Bertamino, Maurizio Simmaco, Marina Borro and Paolo Martelletti

    Citation: The Journal of Headache and Pain 2019 20:56

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  32. Content type: Correction

    After publication of the original article 1, the authors have notified us that the row corresponding to the “Alniditan” drug shouldn’t have been included in Table 1. Table 1 should therefore be presented as be...

    Authors: Thien Phu Do, Song Guo and Messoud Ashina

    Citation: The Journal of Headache and Pain 2019 20:55

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    The original article was published in The Journal of Headache and Pain 2019 20:37

  33. Content type: Review article

    The treatment of migraine is impeded by several difficulties, among which insufficient headache relief, side effects, and risk for developing medication overuse headache (MOH). Thus, new acutely acting antimig...

    Authors: Willem Sebastiaan van Hoogstraten and Antoinette MaassenVanDenBrink

    Citation: The Journal of Headache and Pain 2019 20:54

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  34. Content type: Research article

    Brainstem raphe (BR) hypoechogenicity in transcranial sonography (TCS) has been depicted in patients with major depression (MD) and in depressed patients with different neurodegenerative diseases. But, up to d...

    Authors: Wei-Wei Tao, Xin-Ting Cai, Jie Shen, Xue-Gong Shi and Yu Wang

    Citation: The Journal of Headache and Pain 2019 20:53

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  35. Content type: Review article

    Migraine is a highly prevalent and disabling neurological disorder which is commonly linked with a broad range of psychiatric comorbidities, especially among subjects with migraine with aura or chronic migrain...

    Authors: Thomas Dresler, Salvatore Caratozzolo, Kaat Guldolf, Jana-Isabel Huhn, Carmela Loiacono, Triinu Niiberg-Pikksööt, Marta Puma, Giorgia Sforza, Anna Tobia, Raffaele Ornello and Gianluca Serafini

    Citation: The Journal of Headache and Pain 2019 20:51

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  36. Content type: Review article

    Migraine is a major public health issue associated with significant morbidity, considerable negative impact on quality of life, and significant socioeconomic burden. Preventive treatments are required to reduc...

    Authors: Cindy Tiseo, Raffaele Ornello, Francesca Pistoia and Simona Sacco

    Citation: The Journal of Headache and Pain 2019 20:49

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  37. Content type: Methodology

    Sildenafil and calcitonin gene-related peptide both dilate the intradural segments of the middle meningeal artery measured with 3.0 tesla (T) MR angiography. Here we hypothesized that an increase in field stre...

    Authors: Casper Emil Christensen, Samaira Younis, Ulrich Lindberg, Vincent Oltman Boer, Patrick de Koning, Esben Thade Petersen, Olaf Bjarne Paulson, Henrik Bo Wiberg Larsson, Faisal Mohammad Amin and Messoud Ashina

    Citation: The Journal of Headache and Pain 2019 20:48

    Published on:

    The Correction to this article has been published in The Journal of Headache and Pain 2019 20:62

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