The Journal of Headache and Pain

Aims and scope

The Journal of Headache and Pain is a peer-reviewed open access journal specifically dedicated to researchers involved in all aspects of headache and related pain syndromes, including epidemiology, public health, basic science, translational medicine, clinical trials and real-world data. With a multidisciplinary perspective, The Journal of Headache and Pain covers headache medicine and related pain syndromes in all medical disciplines and particularly encourages clinical, translational and basic science submissions in the areas of pain management, genetics, neurology and internal medicine. Read more.

Article collections

Click here to see the article collections and thematic series that the journal has published in recent years.

Q&A with Authors

Click here to see Q&As with the authors of the journal's most highly viewed articles!

In Review

The Journal of Headache and Pain has launched In Review, a new option that provides authors with on-demand information on the status of their manuscript, enables them to share their work with funders and their research community, and allows their colleagues to comment and collaborate - all whilst their manuscript is under review.

Primary headaches during the COVID-19 lockdown in Germany: analysis of data from 2325 patients using an electronic headache diary

Authors: Bianca Raffaelli, Jasper Mecklenburg, Simon Scholler, Lucas Hendrik Overeem, Ana Sofia Oliveira Gonçalves, Uwe Reuter and Lars Neeb

Content type: Short report

22 June 2021
Thalamo-cortical networks in subtypes of migraine with aura patients

Authors: Gianluca Coppola, Antonio Di Renzo, Emanuele Tinelli, Barbara Petolicchio, Vincenzo Parisi, Mariano Serrao, Camillo Porcaro, Marco Fiorelli, Francesca Caramia, Jean Schoenen, Vittorio Di Piero and Francesco Pierelli

Content type: Research article

19 June 2021
A genetic interaction of NRXN2 with GABRE, SYT1 and CASK in migraine patients: a case-control study

Authors: Miguel Alves-Ferreira, Marlene Quintas, Jorge Sequeiros, Alda Sousa, José Pereira-Monteiro, Isabel Alonso, João Luís Neto and Carolina Lemos

Content type: Research article

14 June 2021
Migraine and neuroinflammation: the inflammasome perspective

Authors: Oguzhan Kursun, Muge Yemisci, Arn M. J. M. van den Maagdenberg and Hulya Karatas

Content type: Review article

10 June 2021
Editorial. Valuing headache’s solution

Authors: TJ Steiner and M Tinelli

Content type: Commentary

10 June 2021

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Headache characteristics in COVID-19 pandemic-a survey study

Authors: Özge Uygun, Mustafa Ertaş, Esme Ekizoğlu, Hayrunnisa Bolay, Aynur Özge, Elif Kocasoy Orhan, Arif Atahan Çağatay and Betül Baykan

Content type: Research article

13 October 2020
Headache medication and the COVID-19 pandemic

Authors: Antoinette MaassenVanDenBrink, Tessa de Vries and A. H. Jan Danser

Content type: Commentary

25 April 2020
Headache associated with cough: a review

Authors: Ann Cordenier, Willem De Hertogh, Jacques De Keyser and Jan Versijpt

Content type: Review article

20 May 2013
Blocking CGRP in migraine patients – a review of pros and cons

Authors: Marie Deen, Edvige Correnti, Katharina Kamm, Tim Kelderman, Laura Papetti, Eloisa Rubio-Beltrán, Simone Vigneri, Lars Edvinsson and Antoinette Maassen Van Den Brink

Content type: Review article

25 September 2017
The red ear syndrome

Authors: Giorgio Lambru, Sarah Miller and Manjit S Matharu

Content type: Review article

4 October 2013

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_{Editorial | 21 February 2018}
Migraine is first cause of disability in under 50s: will health politicians now take notice?
_{Timothy J. Steiner, Lars J. Stovner, Theo Vos, R. Jensen and Z. Katsarava}

_{Research | 05 February 2018}
Long-term study of the efficacy and safety of OnabotulinumtoxinA for the prevention of chronic migraine: COMPEL study
_{Andrew M. Blumenfeld, Richard J. Stark, Marshall C. Freeman, Amelia Orejudos and Aubrey Manack Adams}

_{Consensus article | 16 January 2019}
European headache federation guideline on the use of monoclonal antibodies acting on the calcitonin gene related peptide or its receptor for migraine prevention
^{Simona Sacco, Lars Bendtsen, Messoud Ashina, Uwe Reuter, Gisela Terwindt, Dimos-Dimitrios Mitsikostas and Paolo Martelletti}

_{Research | 01 February 2018}
Poor medical care for people with migraine in Europe – evidence from the Eurolight study
^{Zaza Katsarava, Maka Mania, Christian Lampl, Johanna Herberhold and Timothy J. Steiner}

_{Review | 12 March 2018}
The big CGRP flood - sources, sinks and signalling sites in the trigeminovascular system
^{Karl Messlinger}

_{Review | 09 March 2018}
PACAP and its role in primary headaches
_{Lars Edvinsson, János Tajti, Levente Szalárdy and László Vécsei}

_{Review | 07 August 2018}
PACAP38 and PAC1 receptor blockade: a new target for headache?
_{Eloisa Rubio-Beltrán, Edvige Correnti, Marie Deen, Katharina Kamm, Tim Kelderman, Laura Papetti, Simone Vigneri, Antoinette MaassenVanDenBrink and Lars Edvinsson}

_{Research | 24 May 2018}
Patterns of medicinal cannabis use, strain analysis, and substitution effect among patients with migraine, headache, arthritis, and chronic pain in a medicinal cannabis cohort
^{Eric P. Baron, Philippe Lucas, Joshua Eades and Olivia Hogue}

_{Consensus article | 08 October 2018}
European Headache Federation guideline on idiopathic intracranial hypertension
^{Jan Hoffmann, Susan P Mollan, Koen Paemeleire, Christian Lampl, Rigmor H Jensen and Alexandra J Sinclair}

_{Research | 18 January 2018}
Sphenopalatine ganglion stimulation for cluster headache, results from a large, open-label European registry
^{Mads Barloese, Anja Petersen, Philipp Stude, Tim Jürgens, Rigmor Højland Jensen and Arne May}

_{Publication years: 2018-2019
Source: Web of Science, data collected: March 2020}

European Headache Federation School of Advanced Studies

The European Headache Federation School of Advanced Studies (EHF-SAS) aims to support headache science and offers young EU scientists high quality educational activities to enhance their critical spirit and skills to face headache medicine from a multidisciplinary perspective.

The EHF-SAS covers the richness and diversity of headache medicine fields, including basic science, clinical science, and diagnostic science, and places an emphasis on collaborative projects. The European Headache Federation will support its fellows’ activities allowing them to independently build their own plan sided by the EHF-SAS Scientific Committee.

Editorial Office

Editor in Chief (Founding)
Paolo Martelletti, MD,
Department of Clinical and Molecular Medicine
Sapienza University of Rome
Via di Grottarossa 1035
I-00189 Rome, Italy
Tel.: +39-06-33775111
Fax: +39-06-33775110
E-mail: paolo.martelletti@uniroma1.it

Assistant to the Editor: Valerio De Angelis
E-mail: valerio.deangelis@uniroma1.it

Important for Authors

If you are based in Germany, Hungary, Qatar, Sweden, you may publish your article open access with your fees covered by your institution. Check the list of eligible institutions that are included in the agreements.
If you are a corresponding author affiliated with the University of California (UC), you may be entitled to publish open access in our journals with funding support from the UC libraries.
Go through the Journal submission guidelines and learn about Fees and funding options
Check if your institution has partnered with Springer Nature through the membership program
Visit our OA funding and support service to view our list of research funders and institutions that provide funding for APCs, and to learn more about our email support service.

Featured article: Petasin and isopetasin reduce CGRP release from trigeminal afferents indicating an inhibitory effect on TRPA1 and TRPV1 receptor channels

Featured article: P2X3 receptor upregulation in trigeminal ganglion neurons through TNFα production in macrophages contributes to trigeminal neuropathic pain in rats

Editorial Board Spotlight

Dr Mario Peres is a Neurologist, researcher at Universidade de São Paulo, Instituto de Psiquiatra. His main research interests include headache epidemiology, migraine comorbidity, melatonin and chronobiology, and cluster headaches.

Call for papers

Hot topics in headache and pain from the EHF-SAS

Edited by Prof Paolo Martelletti
Open to submissions

Blogs

It’s not just a headache! A patient’s perspective on the advances in migraine treatment over the last 25 years

05 September 2019
How do sex hormones influence migraine?

02 September 2019
The New Era Of Disease Modifying Migraine Drugs (DMMDs)

01 September 2019

Academic education in headache

The demand for a broad, complete and independent education in Headache Disorders has increased over time. The following international Masters courses guarantee a full coverage of this area of clinical medicine.

For more information:

Master in Headache Medicine
Sapienza University

Master of Headache Disorders
University of Copenhagen