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Celebrating 25 years of The Journal of Headache and Pain

This year marks the 25th anniversary of The Journal of Headache and Pain! We are celebrating the journal's success over the past 25 years and recognising the contributions of scientists from around the world who have made the journal into what it is today.

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Call for papers

AI Advancements in Headache Research: Navigating the Digital Frontier

Edited by: Gianluca Coppola and Igor Petrušić

This collection explores the use of machine learning in migraine research, focusing on advanced algorithms and computational techniques to analyze clinical and neuroimaging data, aiming to uncover patterns and relationships with digital twin solutions.

Endogenous Treatments for Migraine Pain

Edited by: Adriana Della Pietra and Andrew Russo

This collection aims to provide a better understanding of the basic molecular mechanisms of endogenous pain management. This may lead to better and/or alternative migraine pain treatments based on an enhancement of endogenous analgesic systems. 

Headache Burden in Children and Adolescents

Edited by: Marco Antônio Arruda and Timothy J. Steiner

This series will embrace estimates from worldwide of headache-attributed burden, studies characterising the headache disorders of childhood and their evolution throughout adolescence (especially longitudinal cohort studies), those providing insights into the diagnostic uncertainties of child and adolescent headache, and those proposing or evaluating systems of care for child and adolescent headache.

Spreading Depolarization in Headache Disorders

Edited by: Shih Pin Chen and Cenk Ayata

This new collection in The Journal of Headache and Pain invites researchers, clinicians, and academicians to discuss spreading depolarization, exploring its mechanisms, relevance, and implications in both primary and secondary neurological disorders.

Vascular Triggers of Headache Disorders

Edited by: Shih Pin Chen and Cenk Ayata

The Journal of Headache and Pain invites submissions on the interplay between vascular mechanisms and headache, particularly migraine, to our new Collection: Vascular Triggers of Headache.

Gender-Specific Aspects of Headache

Edited by: Antoinette Maassen van den Brink and Bianca Raffaelli

The Journal of Headache and Pain is calling for submissions to our Collection on Gender-Specific Aspects of Headache. This collection aims to explore the multifaceted relationship between gender (as well as biological sex) and headache, encompassing both biological and socio-cultural dimensions.

Article collections

Click here to see the article collections and thematic series that the journal has published in recent years.

From the Junior Editorial Board

Read the reviews on Health equity, care access and quality in headache- Part 1 and Part 2 here!

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Exploring SDG3: Good Health and Wellbeing

Collaborative evidence-based approaches to public policy and healthcare policy and practice are essential, not only in addressing inequalities but also in building trusted sustainable ways forward in which to ensure good health and wellbeing for all. The Journal of Headache and Pain supports submissions that address the SDG3 targets and indicators.

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Visual Abstracts

The Journal of Headache and Pain encourages authors to submit a visual abstract as a supplementary file along with their manuscripts. 

As an author submitting at The Journal of Headache and Pain you are entitled to a 20% discount on professionally produced visual abstracts. Click here to find out more about the service, and your discount will be automatically applied when using this link.

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Aims and scope

The Journal of Headache and Pain is a peer-reviewed open access journal specifically dedicated to researchers involved in all aspects of headache and related pain syndromes, including epidemiology, public health, basic science, translational medicine, clinical trials and real-world data. With a multidisciplinary perspective, The Journal of Headache and Pain covers headache medicine and related pain syndromes in all medical disciplines and particularly encourages clinical, translational and basic science submissions in the areas of pain management, genetics, neurology and internal medicine. Read more

Partnering with the Asian Regional Consortium for Headache (ARCH)

We are delighted to welcome the Asian Regional Consortium for Headache (ARCH) as a partner of The Journal of Headache and Pain. ARCH joins the European Headache Federation and Lifting The Burden in affiliating with the journal.

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  1. Authors: Claudio Tana, Enrico Bentivegna, Soo-Jin Cho, Andrea M. Harriott, David García-Azorín, Alejandro Labastida-Ramirez, Raffaele Ornello, Bianca Raffaelli, Eloísa Rubio Beltrán, Ruth Ruscheweyh and Paolo Martelletti

Top cited articles 2021-2022

Review article | 12 April 2022
The global prevalence of headache: an update, with analysis of the influences of methodological factors on prevalence estimates December 2020
Lars Jacob Stovner, Knut Hagen, Mattias Linde & Timothy J. Steiner

Consensus article | 11 June 2022
European Headache Federation guideline on the use of monoclonal antibodies targeting the calcitonin gene related peptide pathway for migraine prevention-2022 update
Simona Sacco, Faisal Mohammad Amin, Messoud Ashina, Lars Bendtsen, Christina I. Deligianni, Raquel Gil-Gouveia, Zaza Katsarava, Antoinette MaassenVanDenBrink, Paolo Martelletti, Dimos-Dimitrios Mitsikostas, Raffaele Ornello, Uwe Reuter, Margarita Sanchez-del-Rio, Alexandra J. Sinclair, Gisela Terwindt, Derya Uluduz, Jan Versijpt & Christian Lampl 

Review article | 10 June 2021
Migraine and neuroinflammation: the inflammasome perspective
Oguzhan Kursun, Muge Yemisci, Arn M. J. M. van den Maagdenberg & Hulya Karatas 

Research article | 3 May 2021
Galcanezumab for the prevention of high frequency episodic and chronic migraine in real life in Italy: a multicenter prospective cohort study (the GARLIT study)
Fabrizio Vernieri, Claudia Altamura, Nicoletta Brunelli, Carmelina Maria Costa, Cinzia Aurilia, Gabriella Egeo, Luisa Fofi, Valentina Favoni, Giulia Pierangeli, Carlo Lovati, Marco Aguggia, Florindo d’Onofrio, Alberto Doretti, Paola Di Fiore, Cinzia Finocchi, Renata Rao, Francesco Bono, Angelo Ranieri, Maria Albanese, Sabina Cevoli & Piero Barbanti for the GARLIT Study Group

Review article | 14 July 2021
Comorbidities of primary headache disorders: a literature review with meta-analysis
Valeria Caponnetto, Manuela Deodato, Micaela Robotti, Maria Koutsokera, Valeria Pozzilli, Cristina Galati, Giovanna Nocera, Eleonora De Matteis, Gioacchino De Vanna, Emanuela Fellini, Gleni Halili, Daniele Martinelli, Gabriele Nalli, Serena Serratore, Irene Tramacere, Paolo Martelletti & Alberto Raggi On behalf of the European Headache Federation School of Advanced Studies (EHF-SAS)

Research article | 25 October 2021
CGRP monoclonal antibodies in migraine: an efficacy and tolerability comparison with standard prophylactic drugs
Fenne Vandervorst, Laura Van Deun, Annelies Van Dycke, Koen Paemeleire, Uwe Reuter, Jean Schoenen & Jan Versijpt 

Review article | 1 August 2022
Long COVID headache
Claudio Tana, Enrico Bentivegna, Soo-Jin Cho, Andrea M. Harriott, David García-Azorín, Alejandro Labastida-Ramirez, Raffaele Ornello, Bianca Raffaelli, Eloísa Rubio Beltrán, Ruth Ruscheweyh & Paolo Martelletti 

Research article | 21 April 2021
Disability, quality of life, productivity impairment and employer costs of migraine in the workplace
Toshihiko Shimizu, Fumihiko Sakai, Hitoshi Miyake, Tomofumi Sone, Mitsuhiro Sato, Satoshi Tanabe, Yasuhiro Azuma & David W. Dodick 

Short Report | 7 October 2021
Anti-CGRP monoclonal antibodies in chronic migraine with medication overuse: real-life effectiveness and predictors of response at 6 months
Edoardo Caronna, Victor José Gallardo, Alicia Alpuente, Marta Torres-Ferrus & Patricia Pozo-Rosich 

Research article | 3 January 2022
IL-17 crosses the blood-brain barrier to trigger neuroinflammation: a novel mechanism in nitroglycerin-induced chronic migraine
Hao Chen, Xueqian Tang, Jin Li, Bangyan Hu, Wenqin Yang, Meng Zhan, Tengyun Ma & Shijun Xu 

Publication years: 2021-2022
Source: Web of Science, data collected: January 2024

Trending articles

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Editorial Board spotlight

Lanfranco Pellesi, PhD. is a clinical pharmacologist, and Assistant professor at the University of Southern Denmark. He recently obtained his Ph.D. under the supervision of Prof. Ashina investigating the effects of a 2-hour infusion of VIP in healthy volunteers and individuals with migraine without aura. His own research programme aims at elucidating the mechanisms of primary headaches and medication overuse headache through clinical and basic science studies. He spends the rest of his working time leading Pharmacology teaching for medical and pharmaceutical students.

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From the Editors

Analysis of a Success Story (2008-2024)

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In this blog, Prof. Paolo Martelletti, Editor-in-Chief, discusses the recently announced 2023 Journal Citation Reports (JCR) from Clarivate, with regards to The Journal of Headache and Pain

Behind the Paper

The story behind a simple idea: rethinking headache care as a way to improve population health globally

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In this blog, author Alberto Raggi discusses the process of compiling a recently published review in The Journal of Headache and Pain. The review asks, in an era of a changing landscape in global population health, if improving the overall health of people suffering from headache disorders will be a feasible way to improve global population health.

European Headache Federation School of Advanced Studies

The European HeadacheFederation School of Advanced Studies (EHF-SAS) aims to support headache science and offers young EU scientists high quality educational activities to enhance their critical spirit and skills to face headache medicine from a multidisciplinary perspective.

The EHF-SAS covers the richness and diversity of headache medicine fields, including basic science, clinical science, and diagnostic science, and places an emphasis on collaborative projects. The European Headache Federation will support its fellows’ activities allowing them to independently build their own plan sided by the EHF-SAS Scientific Committee.