The Journal of Headache and Pain

Aims and scope

The Journal of Headache and Pain is a peer-reviewed open access journal specifically dedicated to researchers involved in all aspects of headache and related pain syndromes, including epidemiology, public health, basic science, translational medicine, clinical trials and real-world data. With a multidisciplinary perspective, The Journal of Headache and Pain covers headache medicine and related pain syndromes in all medical disciplines and particularly encourages clinical, translational and basic science submissions in the areas of pain management, genetics, neurology and internal medicine. Read more.

COVID-19 and impact on peer review

As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the timelines associated with our peer review process during normal times. Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.

The Greppi Award 2021

Enrico Greppi (1896-1969) Submissions should be made to The Journal of Headache and Pain between 1 March - 30 April 2021 flagging the Greppi Award option as article type.

Learn more here and submit your paper here.

The Italian Society for the Study of Headaches (SISC) announces the competition of the Enrico Greppi Award 2021 – 22^nd Edition. The award will be granted to the best unpublished original paper dealing with clinical, epidemiological, genetic, pathophysiological or therapeutic aspects of headache. The prize amounts to € 5,000 and is open to researchers of all nationalities. The 2021 Award is endorsed by the European Headache Federation (EHF). The winner will be invited to present the paper at The International Headache Congress, to be held in Berlin on 8-12 September 2021.

Q&A with Authors

Click here to see Q&As with the authors of the journal's most highly viewed articles!

Articles

Selective denervation of the corrugator supercilii muscle for the treatment of idiopatic trigeminal neuralgia purely paroxysmal distributed in the supraorbital and suprathrochlear dermatomes

Authors: Alessandro Gualdi, Janos Cambiaso-Daniel, Jonatann Gatti, Ziv M. Peled, Robert Hagan, Dario Bertossi, Paul Wurzer, Lars-Peter Kamolz, Saja Scherer and Giorgio Pietramaggiori

Content type: Research article

4 March 2021
Structural brain network characteristics in patients with episodic and chronic migraine

Authors: Lars Michels, Nabin Koirala, Sergiu Groppa, Roger Luechinger, Andreas R. Gantenbein, Peter S. Sandor, Spyros Kollias, Franz Riederer and Muthuraman Muthuraman

Content type: Research article

3 March 2021
Effect of galcanezumab on severity and symptoms of migraine in phase 3 trials in patients with episodic or chronic migraine

Authors: Michael Ament, Kathleen Day, Virginia L Stauffer, Vladimir Skljarevski, Mallikarjuna Rettiganti, Eric Pearlman and Sheena K. Aurora

Content type: Research article

6 February 2021
Improvements in pain, medication use and quality of life in onabotulinumtoxinA-resistant chronic migraine patients following erenumab treatment – real world outcomes

Authors: J. Talbot, R. Stuckey, L. Crawford, S. Weatherby and S. Mullin

Content type: Research article

9 January 2021
Immunogenicity of biologic therapies for migraine: a review of current evidence

Authors: Joshua M. Cohen, Xiaoping Ning, Yoel Kessler, Michele Rasamoelisolo, Verena Ramirez Campos, Michael J. Seminerio, Lynda J. Krasenbaum, Honglue Shen and Jennifer Stratton

Content type: Review article

7 January 2021

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Headache characteristics in COVID-19 pandemic-a survey study

Authors: Özge Uygun, Mustafa Ertaş, Esme Ekizoğlu, Hayrunnisa Bolay, Aynur Özge, Elif Kocasoy Orhan, Arif Atahan Çağatay and Betül Baykan

Content type: Research article

13 October 2020
Headache medication and the COVID-19 pandemic

Authors: Antoinette MaassenVanDenBrink, Tessa de Vries and A. H. Jan Danser

Content type: Commentary

25 April 2020
Headache associated with cough: a review

Authors: Ann Cordenier, Willem De Hertogh, Jacques De Keyser and Jan Versijpt

Content type: Review article

20 May 2013
The red ear syndrome

Authors: Giorgio Lambru, Sarah Miller and Manjit S Matharu

Content type: Review article

4 October 2013
Blocking CGRP in migraine patients – a review of pros and cons

Authors: Marie Deen, Edvige Correnti, Katharina Kamm, Tim Kelderman, Laura Papetti, Eloisa Rubio-Beltrán, Simone Vigneri, Lars Edvinsson and Antoinette Maassen Van Den Brink

Content type: Review article

25 September 2017

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_{Editorial | 21 February 2018}
Migraine is first cause of disability in under 50s: will health politicians now take notice?
_{Timothy J. Steiner, Lars J. Stovner, Theo Vos, R. Jensen and Z. Katsarava}

_{Research | 05 February 2018}
Long-term study of the efficacy and safety of OnabotulinumtoxinA for the prevention of chronic migraine: COMPEL study
_{Andrew M. Blumenfeld, Richard J. Stark, Marshall C. Freeman, Amelia Orejudos and Aubrey Manack Adams}

_{Consensus article | 16 January 2019}
European headache federation guideline on the use of monoclonal antibodies acting on the calcitonin gene related peptide or its receptor for migraine prevention
^{Simona Sacco, Lars Bendtsen, Messoud Ashina, Uwe Reuter, Gisela Terwindt, Dimos-Dimitrios Mitsikostas and Paolo Martelletti}

_{Research | 01 February 2018}
Poor medical care for people with migraine in Europe – evidence from the Eurolight study
^{Zaza Katsarava, Maka Mania, Christian Lampl, Johanna Herberhold and Timothy J. Steiner}

_{Review | 12 March 2018}
The big CGRP flood - sources, sinks and signalling sites in the trigeminovascular system
^{Karl Messlinger}

_{Review | 09 March 2018}
PACAP and its role in primary headaches
_{Lars Edvinsson, János Tajti, Levente Szalárdy and László Vécsei}

_{Review | 07 August 2018}
PACAP38 and PAC1 receptor blockade: a new target for headache?
_{Eloisa Rubio-Beltrán, Edvige Correnti, Marie Deen, Katharina Kamm, Tim Kelderman, Laura Papetti, Simone Vigneri, Antoinette MaassenVanDenBrink and Lars Edvinsson}

_{Research | 24 May 2018}
Patterns of medicinal cannabis use, strain analysis, and substitution effect among patients with migraine, headache, arthritis, and chronic pain in a medicinal cannabis cohort
^{Eric P. Baron, Philippe Lucas, Joshua Eades and Olivia Hogue}

_{Consensus article | 08 October 2018}
European Headache Federation guideline on idiopathic intracranial hypertension
^{Jan Hoffmann, Susan P Mollan, Koen Paemeleire, Christian Lampl, Rigmor H Jensen and Alexandra J Sinclair}

_{Research | 18 January 2018}
Sphenopalatine ganglion stimulation for cluster headache, results from a large, open-label European registry
^{Mads Barloese, Anja Petersen, Philipp Stude, Tim Jürgens, Rigmor Højland Jensen and Arne May}

_{Publication years: 2018-2019
Source: Web of Science, data collected: March 2020}

European Headache Federation School of Advanced Studies

The European Headache Federation School of Advanced Studies (EHF-SAS) aims to support headache science and offers young EU scientists high quality educational activities to enhance their critical spirit and skills to face headache medicine from a multidisciplinary perspective.

The EHF-SAS covers the richness and diversity of headache medicine fields, including basic science, clinical science, and diagnostic science, and places an emphasis on collaborative projects. The European Headache Federation will support its fellows’ activities allowing them to independently build their own plan sided by the EHF-SAS Scientific Committee.

Editorial Office

Editor in Chief (Founding)
Paolo Martelletti, MD,
Department of Clinical and Molecular Medicine
Sapienza University of Rome
Via di Grottarossa 1035
I-00189 Rome, Italy
Tel.: +39-06-33775111
Fax: +39-06-33775110
E-mail: paolo.martelletti@uniroma1.it

Assistant to the Editor: Valerio De Angelis
E-mail: valerio.deangelis@uniroma1.it

Article collections

Click here to see the article collections and thematic series that the journal has published in recent years.

Featured article: Immunogenicity of biologic therapies for migraine: a review of current evidence

Featured article: Metabotropic glutamate receptor 5 regulates synaptic plasticity in a chronic migraine rat model through the PKC/NR2B signal

In Review

The Journal of Headache and Pain has launched In Review, a new option that provides authors with on-demand information on the status of their manuscript, enables them to share their work with funders and their research community, and allows their colleagues to comment and collaborate - all whilst their manuscript is under review.

Hot topics in headache and pain from the EHF-SAS

Edited by Prof Paolo Martelletti
Open to submissions

Editorial Board Spotlight

Dr. Alberto Raggi is a researcher at the Neurological Institute Carlo Besta IRCCS Foundation of Milan (Italy). His main research interests include behavioral treatments for headaches, the evaluation of patient-reported outcome measures and the evaluation of burden of headache disorders based on GBD estimates.

Blogs

It’s not just a headache! A patient’s perspective on the advances in migraine treatment over the last 25 years

05 September 2019
How do sex hormones influence migraine?

02 September 2019
The New Era Of Disease Modifying Migraine Drugs (DMMDs)

01 September 2019

Academic education in headache

The demand for a broad, complete and independent education in Headache Disorders has increased over time. The following international Masters courses guarantee a full coverage of this area of clinical medicine.

For more information:

Master in Headache Medicine
Sapienza University
Academic Year 2020-2021

Master of Headache Disorders
University of Copenhagen
Academic Years 2018-2020