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  1. If migraine or a migrainelike headache and stroke occur together, it is difficult to determine whether migraine is the cause of the stroke or stroke is the cause of symptomatic migraine. We report the case of...

    Authors: Josef G. Heckmann, Christoph J.G. Lang, Margarete Weber, Bernd Tomandl and Bernhard Neundörfer
    Citation: The Journal of Headache and Pain 2003 4:00026
    Content type: BRIEF REPORT Published on:

  2. Familial hemiplegic migraine (FHM) is a rare autosomal dominant-type migraine with aura. Attacks are characterised by hemiparesis in addition to other aura and migraine symptoms. Few studies have examined the...

    Authors: Michele Roccella
    Citation: The Journal of Headache and Pain 2003 4:00025
    Content type: ORIGINAL Published on:

  3. We observed the occurrence of neuromuscular hyperexcitability, assessed with electromyographic ischemic tests, in headache patients in relation to Mg++ levels in serum, red blood cells and mononuclear cells. Cli...

    Authors: Giovanni Mazzotta, Paola Sarchielli, Andrea Alberti, Elisabetta Cittadini and Virgilio Gallai
    Citation: The Journal of Headache and Pain 2003 4:00024
    Content type: ORIGINAL Published on:

  4. The main goals of prophylactic treatment for migraine are to decrease headache attack frequency, length and intensity, to improve the efficacy of symptomatic drugs, to reduce their need, and to prevent pain c...

    Authors: Emilio Sternieri, Anna Ferrari and Arrigo F.G. Cicero
    Citation: The Journal of Headache and Pain 2003 4:00022
    Content type: REVIEW Published on:

  6. The role of daily analgesic use (also called abuse) in chronic daily headache (CDH) for the maintenance of chronic headache is discussed. The comprehension of the underlying mechanisms of actions is lacking m...

    Authors: Luigi A. Pini
    Citation: The Journal of Headache and Pain 2003 4:00020
    Content type: EDITORIAL Published on:

  7. Triptans are presently a milestone in the treatment of migraine patients. Because of their effectiveness and safety, they have radically improved migraine treatment but their use has meant a substantial incre...

    Authors: Giuseppe Stirparo, Fabio Palazzo, Sergio De Filippis and Paolo Martelletti
    Citation: The Journal of Headache and Pain 2003 4(Suppl 1):00019
    Content type: SELECTED PRESENTATION Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  8. Headache represents not only an individual disease, but also an important pathology for society because its prevalence in the population is about 50.0%. Its physical, emotional, social and economic impacts ar...

    Authors: Stefania Iannazzo, Maria S. Cattaruzza, Sergio De Filippis, Flora Rossi, Edea Perata, Samanta Di Rollo, Gabriella Coloprisco and Paolo Martelletti
    Citation: The Journal of Headache and Pain 2003 4(Suppl 1):00018
    Content type: SELECTED PRESENTATION Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  9. Although headache is a common complaint, only few sufferers seek specific medical assistance. Migraine is one of the most frequently encountered varieties of headache. The first presentation of migraine is im...

    Authors: Rosario Iannacchero, Umberto Cannistrà, Rita L. Trinchi, Antonio La Vitola, Francesco Peltrone and Emilio De Caro
    Citation: The Journal of Headache and Pain 2003 4(Suppl 1):00017
    Content type: SELECTED PRESENTATION Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  10. The World Headache Alliance (WHA) works to reduce the burden of headache worldwide. Headache disorders are real, common and affect people of all ages, everywhere in the world. To reduce the burden resulting f...

    Authors: Audrey Craven and Kary Shannon
    Citation: The Journal of Headache and Pain 2003 4(Suppl 1):00016
    Content type: PUBLIC AND LAY ORGANIZATIONS Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  11. Headache is the most frequent reason for neurological consultation, but also a comorbidity often encountered by GPs. The costs of headache are considerable: direct and indirect costs contribute to varying deg...

    Authors: Antonietta Citterio, Grazia Sances, Giorgio Sandrini, Tiziana Repossi and Giuseppe Nappi
    Citation: The Journal of Headache and Pain 2003 4(Suppl 1):00015
    Content type: PUBLIC AND LAY ORGANIZATIONS Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  12. Health services are rarely highly successful in meeting the needs of people with headache disorders, who everywhere are low in the priority queue. Taking the UK as an example within Europe, this paper briefly...

    Authors: Timothy J. Steiner
    Citation: The Journal of Headache and Pain 2003 4(Suppl 1):00014
    Content type: PUBLIC AND LAY ORGANIZATIONS Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  13. Triptans are presently a milestone in the treatment of migraine patients. Because of their effectiveness and safety, they have radically improved migraine treatment but their use has meant a substantial incre...

    Authors: Pietro Folino-Gallo, Fabio Palazzo, Giuseppe Stirparo, Sergio De Filippis and Paolo Martelletti
    Citation: The Journal of Headache and Pain 2003 4(Suppl 1):00013
    Content type: PHARMACOECONOMY Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  14. The major aim of the paper is to give an epidemiologist's viewpoint on several points related to the evaluation of the costs of migraine and to answer some questions that are important if one wishes to decrea...

    Authors: Jean François Dartigues, Philippe Michel and Patrick Henry
    Citation: The Journal of Headache and Pain 2003 4(Suppl 1):00012
    Content type: PHARMACOECONOMY Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  15. The EuroMedicines Project created a single drug directory at a single time point (late 1998) to cover most of the member states of the European Union (EU) and some of the candidate states, so as to aid drug r...

    Authors: Tom Walley
    Citation: The Journal of Headache and Pain 2003 4(Suppl 1):00011
    Content type: PHARMACOECONOMY Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  16. The term “disease costing” applies to those economic appraisal methodologies that ascertain the cost borne by a community because of a disease. This approach has been used to calculate the social and economic...

    Authors: Amalia Donia Sofio, Franco Mazzuca and Francesco S. Mennini
    Citation: The Journal of Headache and Pain 2003 4(Suppl 1):00010
    Content type: PHARMACOECONOMY Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  17. Information on the prevalence and health burden of headache in Africa is scanty. Earlier studies in the 1970s suggested that migraine was a rare condition in the African. This may have been due to an underdia...

    Authors: Redda Tekle Haimanot
    Citation: The Journal of Headache and Pain 2003 4(Suppl 1):00009
    Content type: SPECIAL LECTURE Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  18. Migraine is associated with functional impairment. The migraine disability assessment (MIDAS) questionnaire is a scientific instrument which captures headache-related disability. The Italian version of MIDAS ...

    Authors: Domenico D'Amico and Gennaro Bussone
    Citation: The Journal of Headache and Pain 2003 4(Suppl 1):00008
    Content type: INTANGIBLE COSTING Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  19. Population-based studies have shown that migraineurs have reduced HRQoL independent of depression. Furthermore, HRQoL is reduced with increasing migraine attack frequency. In both population-based and clinic-...

    Authors: Gisela M. Terwindt, Michel D. Ferrari and Lenore J. Launer
    Citation: The Journal of Headache and Pain 2003 4(Suppl 1):00007
    Content type: INTANGIBLE COSTING Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  20. Measuring population health is important to evaluate the impact of interventions, to monitor the changes in health status, and to predict the need for health care. A number of tools have been developed to mea...

    Authors: Paola Mosconi and Giovanni Apolone
    Citation: The Journal of Headache and Pain 2003 4(Suppl 1):00006
    Content type: INTANGIBLE COSTING Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  21. Economic evaluation of health care programs or technologies requires distinguishing three types of costs: direct, indirect and human. The first two types do not imply peculiar methodological issues to quantif...

    Authors: Fabio Palazzo, Giuseppe Stirparo and Lorenzo Terranova
    Citation: The Journal of Headache and Pain 2003 4(Suppl 1):00005
    Content type: INTANGIBLE COSTING Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  22. Comorbidity of migraine is important from a number of different perspectives. Co-occurrence of different diseases may complicate diagnosis as a high degree of symptomatic overlap may occur among conditions as...

    Authors: Antonio Carolei, Irene Ciancarelli, Davide Cerone and Simona Sacco
    Citation: The Journal of Headache and Pain 2003 4(Suppl 1):00004
    Content type: GLOBAL BURDEN Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  23. One-year migraine prevalence rates in the general population for Western countries vary from 4% to 9% in men and from 11% to 25% in women. Non-Western countries report lower figures. Incidence rates for peopl...

    Authors: Gian Camillo Manzoni and Paola Torelli
    Citation: The Journal of Headache and Pain 2003 4(Suppl 1):00003
    Content type: GLOBAL BURDEN Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  24. This paper briefly describes some of the work developed by the World Health Organization in the field of health, disability and burden of diseases and how this work has relevant implications for migraine and,...

    Authors: Matilde Leonardi
    Citation: The Journal of Headache and Pain 2003 4(Suppl 1):00002
    Content type: GLOBAL BURDEN Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  25. Migraine is a highly prevalent headache disorder that has a substantial impact on the individual and on society. Over the past decade, substantial advances in research have increased understanding of the path...

    Authors: Richard B. Lipton, Marcelo E. Bigal, Ann I. Scher and Walter F. Stewart
    Citation: The Journal of Headache and Pain 2003 4(Suppl 1):00001
    Content type: GLOBAL BURDEN Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  28. SUNCT syndrome (shortlasting unilateral neuralgiform headache attacks with conjunctival injection and tearing) is a rare, debilitating headache that is difficult to be treated. We describe a SUNCT patient, in...

    Authors: Piero Meineri, Fiorella Mondino and Enzo Grasso
    Citation: The Journal of Headache and Pain 2002 3:00034
    Content type: BRIEF REPORT Published on:

  29. The focus of this paper is the family factors associated with primary headache in children between 8 and 14 years. We studied the differences in the family ecology between 32 children with headaches and 32 he...

    Authors: Ursula Napoli, Vanna Axia and Pier Antonio Battistella
    Citation: The Journal of Headache and Pain 2002 3:00033
    Content type: ORIGINAL Published on:

  30. Menstrual migraine (MM) pathogenesis has not yet been clarified, even though several hypotheses have been formulated. In the present research, we investigated cerebral blood flow in 15 patients with MM. Brain...

    Authors: Bašak Karakurum, Seniha Naldöken, Hülya Ortapamuk, Serap Üčler and Levent E. İnan
    Citation: The Journal of Headache and Pain 2002 3:00032
    Content type: ORIGINAL Published on:

  31. The blockade of the greater occipital nerve (GON) has been used in the treatment of migraine without aura (MWOA), tension-type headache (TTH) and cervicogenic headache (CH). There have been only a few reports...

    Authors: Tansel Terzi, Bašak Karakurum, Serap Üçler, Levent E. İnan and Cankat Tulunay
    Citation: The Journal of Headache and Pain 2002 3:00031
    Content type: ORIGINAL Published on:

  32. Little has been done to investigate the biochemical basis of chronic daily headache (CDH). Our group has recently demonstrated an increase in the cerebrospinal fluid (CSF) levels of nerve growth factor (NGF) ...

    Authors: Paola Sarchielli, Andrea Alberti, Beatrice Gallai, Francesca Coppola, Antonio Baldi, Ardesio Floridi and Virgilio Gallai
    Citation: The Journal of Headache and Pain 2002 3:00030
    Content type: ENRICO GREPPI AWARD Published on:

  33. Current severity (intensity) grading in headache is based upon a 4-grade category scale that includes the zero grade. For ordinary scientific and practical work, a low-sensitivity scale may suffice. However, ...

    Authors: Ottar Sjaastad, T.A. Fredriksen, H.C. Petersen and L.S. Bakketeig
    Citation: The Journal of Headache and Pain 2002 3:00029
    Content type: SPECIAL ARTICLE Published on:

  36. The objective of our study is to report the frequency and characteristics of cluster headache with aura among the population of patients with cluster headache treated in our outpatient neurology clinic. 254 p...

    Authors: Eva Martínez-Fernández, Roman Alberca, Pablo Mir, Emilio Franco, Enrique Montes and Pilar Lozano
    Citation: The Journal of Headache and Pain 2002 3:00026
    Content type: BRIEF REPORT Published on:

  38. We examined the efficacy of physical therapy and adjunctive botulinum toxin type A (BTX-A) injections in the treatment of cervical headache. We performed a doubleblind, randomised, placebo-controlled study ov...

    Authors: Peter Schnider, Ecaterina Moraru, Marion Vigl, Christian Wöber, Daniela Földy, Joachim Maly, Christian Bittner, Peter Wessely and Eduard Auff
    Citation: The Journal of Headache and Pain 2002 3:00024
    Content type: ORIGINAL Published on:

  39. Based on the knowledge that migraine and tension-type headache (TTH) are associated with reduced effectiveness at work and impairment of function in social roles, we studied the different influences that thes...

    Authors: Konstantinidos Vadikolias, Ioannis Heliopoulos, Grigorios Tripsianis, Athanasios Achtaropoulos, Elias Homsioglou, Nickolaos Artemis, Haritomeni Piperidou and Ioannis Milonas
    Citation: The Journal of Headache and Pain 2002 3:00023
    Content type: ORIGINAL Published on:

  40. Twenty-three patients, aged 18‐66 years and suffering from migraine with or without aura, were randomly selected to receive either vigabatrin or matched placebo tablets first for 12 weeks in a double-blind cr...

    Authors: Karabi Ghose, Brian E. Niven and Dave Berry
    Citation: The Journal of Headache and Pain 2002 3:00022
    Content type: ORIGINAL Published on:

  41. Cluster headache (CH) is the most frequent primary trigeminal autonomic cephalalgia (Goadsby, 2001). Clinical symptoms have been clearly identified and are described in the IHS classification. Cluster-like he...

    Authors: Pierric Giraud, Emmanuel Jouanneau, Françoise Borson-Chazot, Michel Lanteri-Minet and Guy Chazot
    Citation: The Journal of Headache and Pain 2002 3:00021
    Content type: REVIEW Published on:

  42. The clinical questions posed by the advent of acute migraine-specific treatment (triptans) are on which patient to use specific treatment for migraine, and when in the attack to treat patients. Three strategi...

    Authors: Stewart J. Tepper, Alan M. Rapoport and Fred Sheftell
    Citation: The Journal of Headache and Pain 2002 3:00020
    Content type: REVIEW Published on:

  46. Authors: Peter Hallas
    Citation: The Journal of Headache and Pain 2001 2:10020100.10194
    Content type: Published on:

  47. Headache is the most frequent symptom in patients with cerebral venous thrombosis. However, patients presenting with headache due to cerebral venous thrombosis are uncommon. The association between oral contr...

    Authors: Enrico Tessitore, Claudio Schonauer, Francesco Fera and Alessandro Tessitore
    Citation: The Journal of Headache and Pain 2001 2:10020097.10194
    Content type: Case report Published on:

  49. The aim of this open study was to make a preliminary estimate of the efficacy and tolerability of intravenously administered magnesium sulfate (1 g) in comparison to subcutaneously administered sumatriptan in...

    Authors: Jasna Zidverc-Trajković, Aleksandra M. Pavlović, Zagorka Jovanović, Nadežda Šternić and Vladimir S. Kostić
    Citation: The Journal of Headache and Pain 2001 2:10020079.10194
    Content type: Original Published on:

  50. The involvement of nitric oxide (NO) in the pathophysiology of primary headaches was suggested by several authors during the last decade. Migraine, cluster headache, tension headache, and cervicogenic headach...

    Authors: Alessandra Zicari, Mario Giacovazzo and Paolo Martelletti
    Citation: The Journal of Headache and Pain 2001 2:10020067.10194
    Content type: Review Published on:
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