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A patient with SUNCT syndrome responsive to sodium valproate


SUNCT syndrome (shortlasting unilateral neuralgiform headache attacks with conjunctival injection and tearing) is a rare, debilitating headache that is difficult to be treated. We describe a SUNCT patient, initially treated with lamotrigine, with a positive response but with an unbearable side-effect (somnolence) that lead to withdrawal. The drug was replaced with sodium valproate at a dosage of 1000 mg b.i.d.. Complete remission of the attacks has been obtained for 1 year, without significant side effects.

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Received: 24 July 2001, Accepted in revised form: 10 January 2002

Correspondence to P. Meineri

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Meineri, P., Mondino, F. & Grasso, E. A patient with SUNCT syndrome responsive to sodium valproate. J Headache Pain 3, 155–157 (2002).

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  • Key words SUNCT
  • Valproate
  • Treatment