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Neuropsychologic phenotypes in familial hemiplegic migraine


Familial hemiplegic migraine (FHM) is a rare autosomal dominant-type migraine with aura. Attacks are characterised by hemiparesis in addition to other aura and migraine symptoms. Few studies have examined the influence of FHM on cognitive functions. This study was aimed to investigate neuropsychological functions in 3 adolescent siblings suffering from FHM assessed six months after the last attack. No relevant deficits were found on a battery of multisectorial tests exploring cognitive functions. Sporadic FHM attack therefore seems not to affect cognition in these patients, at least far from the crises.

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Received: 9 January 2002, Accepted in revised form: 10 January 2003

Correspondence to M. Roccella

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Roccella, M. Neuropsychologic phenotypes in familial hemiplegic migraine. J Headache Pain 4, 31–36 (2003).

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  • Key words Familial hemiplegic migraine
  • Neuropsychologic phenotypes
  • Cognitive functions