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  2. DC MEG shifts, similar and complex in waveform, were observed in visually induced migraine with aura patients similar to spontaneous aura but not controls. Multiple cortical areas were activated in visually in...

    Authors: K. Michael A. Welch, Susan M. Bowyer, Sheena K. Aurora, John E. Moran and Norman Tepley
    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):26
    Content type: KEY NOTE LECTURE Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  3. The Italian Society for the Study of Headaches (SISC) published the first guidelines for diagnosis and treatment of migraine in 1993. In 2000, the Executive Committee of the SISC decided to provide updated dia...

    Authors: Virgilio Gallai and Paola Sarchielli
    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):25
    Content type: THERAPY Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  4. Anticonvulsant drugs have been used in migraine prophylaxis since 1970. In recent years, new antiepileptic compounds have given rise to much interest in pain control. Migraine prophylaxis is still based on old...

    Authors: Fabio Frediani, Francesca Cominelli and Manlio Sgarzi
    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):24
    Content type: THERAPY Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  5. An association between migraine and menstruation can be ascertained by use of a diary for a minimum of three cycles. The pathophysiological and clinical peculiarities of menstrual migraine indicate that its ma...

    Authors: Franca Moschiano, Licia Grazzi, Domenico D’Amico, Ferdinando Schieroni and Gennaro Bussone
    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):23
    Content type: THERAPY Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  6. There is no consensus on which treatment strategy should be used in the acute therapy of migraine. A stratified care approach based on patient’s disabilty assessed by a valid instrument (the MIDAS questionnair...

    Authors: Sergio Genco, Domenico D’Amico, Franca Moschiano, Maria Pia Prudenzano, Paola Mosconi, Elena Floriani, Ferdinando Schieroni and Gennaro Bussone
    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):22
    Content type: THERAPY Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  7. Many drugs are now available for treating migraine attacks, including agents specifically indicated for this condition. Since 1990 sumatriptan, the first 5–HT1B,1D receptor agonist, was introduced and realized a ...

    Authors: Giorgio Zanchin, Filippo Dainese, Federico Mainardi and Ferdinando Maggioni
    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):21
    Content type: THERAPY Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  8. Despite the pharmacokinetic differences among triptans and the variety of ways of administration, the clinical differences in every day use of these drugs lack in an accepted decisional tree. In fact, there ar...

    Authors: Luigi Alberto Pini and Arrigo F. G. Cicero
    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):20
    Content type: THERAPY Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  9. The introduction of triptans, in the early 1990s, has improved the therapy for acute migraine attack, offering a new quality of life for those patients who suffer from this disabling neurological disorder. Epi...

    Authors: Dario Calderoni, Federica Galli and Vincenzo Guidetti
    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):19
    Content type: THERAPY Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  10. Since the observation that sumatriptan, the first triptan to be synthetized as a specific antimigraine compound, was able to block neurogenic inflammation (NI) in intra– and extracranial rat tissues, the exper...

    Authors: M. Gabriella Buzzi
    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):18
    Content type: THERAPY Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  11. The current review providesa brief summary of the key pre–clinical and clinical characteristics of the triptans that might influence the choice of drug. Data from extensive clinical trials tentatively suggest ...

    Authors: Alan M. Rapoport and Stewart J. Tepper
    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):17
    Content type: KEY NOTE LECTURE Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  12. This paper reviews the literature of genetic epidemiology in primary headaches. Migraine without aura and migraine with aura are distinct disorders. Both are caused by a combination of genetic and environmental f...

    Authors: Michael Bjørn Russell
    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):16
    Content type: KEY NOTE LECTURE Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  13. Migraine is currently considered to be a multifactorial disease in that it is modified by environmental and genetic factors and has a polygenic determination. Familial hemiplegic migraine (FHM), a subtype of m...

    Authors: Pasquale Montagna
    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):15
    Content type: MIGRAINE AND PATHOPHYSIOLOGY Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  14. Migraine, characterized by several autonomic disturbances both during and between attacks, suggests an involvement of the autonomic nervous system (ANS). To clarify the role of the ANS in migraine pathogenesis...

    Authors: Pietro Cortelli, Sabina Cevoli, Giuseppe Bonavina, Fabiola Magnifico and Giulia Pierangeli
    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):14
    Content type: MIGRAINE AND PATHOPHYSIOLOGY Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  15. We review the main electrophysiological abnormalities emerging from migraine studies and discuss them from the pathophysiological point of view. Considerations range from genetic aspects to the heterogeneous c...

    Authors: Giorgio Sandrini, Alberto Proietti Cecchini, Sonya Ivanova Hristova, Grazia Sances and Giuseppe Nappi
    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):13
    Content type: MIGRAINE AND PATHOPHYSIOLOGY Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  16. Modification in platelet activation and aggregation has been demonstrated in migraine patients both during and between attacks. A different pattern in the secretion of platelet products has also been observed ...

    Authors: Paola Sarchielli and Virgilio Gallai
    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):12
    Content type: MIGRAINE AND PATHOPHYSIOLOGY Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  17. Nitric oxide (NO) probably plays an important role in the pathogenesis of migraine without aura (MWA). As the activation of NO–ergic cascade has been shown to be closely linked to cyclooxygenase pathway and to...

    Authors: Paolo Martelletti, Alessandra Zicari, Massimo Realacci, Giuseppe Fiore, Sergio De Filippis, Giuseppe Stirparo, Paola Denora, Maria Donata Solimeo, Cristina Rinaldi, Stefania Morrone and Mario Giacovazzo
    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):10
    Content type: MIGRAINE AND PATHOPHYSIOLOGY Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  18. Serotonin (5–HT) and serotonin receptors play an important role in migraine pathophysiology. Changes in platelet 5–HT content are not casually related, but they may reflect similar changes at a neuronal level....

    Authors: Massimo Leone, Andrea Rigamonti, Domenico D’Amico, Licia Grazzi, Susanna Usai and Gennaro Bussone
    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):8
    Content type: MIGRAINE AND PATHOPHYSIOLOGY Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  19. Migraine is associated with functional impairment. The migraine disability assessment (MIDAS) scale is a scientific instrument which captures headache–related disability. The Italian version of MIDAS was devel...

    Authors: Gennaro Bussone, Licia Grazzi, Susanna Usai, Paola Mosconi, Sergio Genco, Franco Michele Puca and Domenico D’Amico
    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):6
    Content type: MIGRAINE AND DISABILITY Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  20. Although the genuine interest in measuring qualitative aspects of life has increased in the medical field together with our capability to transform patients’ subjective reports, opinions and ratings in standar...

    Authors: Giovanni Apolone and Paola Mosconi
    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):4
    Content type: MIGRAINE AND DISABILITY Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  21. The 1988 International Headache Society (IHS) classification has greatly contributed to overcoming the obstacles that had made it difficult in the past to compare results of surveys on headache epidemiology. F...

    Authors: Gian Camillo Manzoni and Paola Torelli
    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):2
    Content type: MIGRAINE AND DISABILITY Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  22. In the past decade researchers have become increasingly interested in quality of life as it pertains to headache, in particular migraine. A number of general health or well–being measures and migraine–specific...

    Authors: Frank Andrasik
    Citation: The Journal of Headache and Pain 2001 2(Suppl 1):1
    Content type: KEY NOTE LECTURE Published on:

    This article is part of a Supplement: Volume 2 Supplement 1

  24. The present case report underlies the importance of modifications in the characteristics of post-lumbar puncture headache, which led us to diagnose cerebral venous thrombosis in a 34-year-old woman affected b...

    Authors: Andrea Giorgetti, Maria Vittoria Calloni, Roberto Freschi, Giuseppe Mariani, Patrizia Perrone, Patrizia Secchi and Adriana Sermoni
    Citation: The Journal of Headache and Pain 2001 2:10020045.10194
    Content type: Brief report Published on:

  25. Helicobacter pylori (H. pylori) has been recently associated with some organic and functional vascular disorders. In particular, our group found a high prevalence of H. pylori in patients affected by migraine an...

    Authors: Maurizio Gabrielli, Francesco Franceschi, Giuseppe Fiore, Marcello Candelli, Alessandro Armuzzi, Veronica Ojetti, Filippo Cremonini, Paolo Pola, Mario Giacovazzo and Antonio Gasbarrini
    Citation: The Journal of Headache and Pain 2001 2:10020039.10194
    Content type: Original Article Published on:

  26. The aim our work was to study the personality profile and alexithymic syndrome (based on the analysis of seven specific markers) of primary headache patients through the Rorschach test. 240 headache patients ...

    Authors: Vincenzo Pizza, Daniele L.A. Spitaleri and Cesare Colucci d'Amato
    Citation: The Journal of Headache and Pain 2001 2:10020031.10194
    Content type: Original Article Published on:

  27. Headache occurs frequently in acute ischemic stroke, but its frequency varies widely among different studies. We have prospectively studied headache features in patients with first-ever ischemic acute stroke ...

    Authors: Maurizio Paciaroni, Lucilla Parnetti, Paola Sarchielli and Virgilio Gallai
    Citation: The Journal of Headache and Pain 2001 2:10020025.10194
    Content type: Original Article Published on:

  28. Sensitization of myofascial pain pathways may play an important role in the pathophysiology of chronic headache. Animal studies have shown that sensitization of pain pathways may be caused by associated with ...

    Authors: Messoud Ashina and Lars Bendtsen
    Citation: The Journal of Headache and Pain 2001 2:10020021.10194
    Content type: Review Published on:

  30. Sumatriptan and the newer triptans (zolmitriptan, naratriptan, rizatriptan, eletriptan, almotriptan, frovatriptan and donitriptan) display high agonist activity at 5-HT1B and 5-HT1D receptors. Most triptans, but...

    Authors: Pramod R. Saxena and Peer Tfelt-Hansen
    Citation: The Journal of Headache and Pain 2001 2:10020003.10194
    Content type: Review Published on:

  32. Circumstantial evidence points to the possible role of magnesium (Mg+2) deficiency in the pathogenesis of migraine and has raised questions about the clinical utility of magnesium as a therapeutic regimen in mig...

    Authors: Seref Demirkaya, Babur Dora, Mehmet Akif Topcuoglu, U. Hıdır Ulas and Okay Vural
    Citation: The Journal of Headache and Pain 2000 1:00010179.10194
    Content type: Original article Published on:

  34. Migraine without aura (MWOA) and migraine with aura (MWA) are disorders in which multiple factors, including environmental and genetic factors, are involved. In a previous study we hypothesized a protective r...

    Authors: Paolo Martelletti, Gloria Brioli, Patrizia Lulli, Marina Morellini, Mario Giacovazzo and Simonetta Trabace
    Citation: The Journal of Headache and Pain 2000 1:00010119.10194
    Content type: Rapid communication Published on:

  35. Our purpose was to apply the Minnesota Multiphasic Personality Inventory (MMPI-2) to groups of women with different types of headache and facial pain. 117 women with tension-type headache (TTH), migraine (M),...

    Authors: Franco Mongini, Erika Barbalonga and Fabio Raviola
    Citation: The Journal of Headache and Pain 2000 1:00010105.10194
    Content type: Original article Published on:

  36. The trigeminovascular system is considered to play a role in the mechanism of migraine headache. Novel in vitro animal models that investigate the release of neuropeptides may be of help to understand the pat...

    Authors: Michele Tognetto, Christophe Creminon, Silvia Amadesi, Marcello Trevisani, Gloria Giovannini, Adriano Piffanelli and Pierangelo Geppetti
    Citation: The Journal of Headache and Pain 2000 1:00010083.10194
    Content type: Original article Published on:

  38. The basic physiological and anatomical basis for circadian rhythms in mammalian behaviour and physiology is introduced. The pathways involved in photic entrainment of the circadian clock are discussed in rela...

    Authors: Mauro Zordan and Charalambos P. Kyriacou
    Citation: The Journal of Headache and Pain 2000 1(Suppl 2):103
    Content type: OriginalPaper Published on:

    This article is part of a Supplement: Volume 1 Supplement 2

    The Erratum to this article has been published in The Journal of Headache and Pain 2005 6:Art1

  39. Chronic daily headache (CDH) in children and adolescents presents features not sufficiently recognized by the current classification system. The aim of our study was to analyze the applicability of adult CDH c...

    Authors: Vincenzo Guidetti, Federica Galli, Rita Cerutti and Paola Fabrizi
    Citation: The Journal of Headache and Pain 2000 1(Suppl 1):0001S089.10194
    Content type: Published on:

    This article is part of a Supplement: Volume 1 Supplement 1

  40. Chronic pathologies, above all those in which is present pain, can induce a considerable impairment in quality of life. The concept of illness behaviour is closely related to that of quality of life. It can b...

    Authors: Maria Pia Prudenzano, Mario Guazzelli, Anna Pia Verri, Salvatore Misceo, Vittorio Sciruicchio, Giuseppe Libro, Maria Nicolodi, Stefania Canova, Franca Moschiano, Licia Grazzi, Domenico D'Amico, Ferdinando Maggioni, Giuliano Relja, Giorgio Sandrini, Andrea Alberti and Susanna Russo
    Citation: The Journal of Headache and Pain 2000 1(Suppl 1):0001S061.10194
    Content type: Published on:

    This article is part of a Supplement: Volume 1 Supplement 1

  41. The psychopathological approach is fundamental in the study of chronic headache because it integrates the diagnosis of a pathology in which the symptom (headache) is the disease itself hiding in itself the de...

    Authors: Caterina Firenze, Maria Pia Prudenzano, Sergio Genco, Mariantonietta Savarese, Francomichele Puca, Maria Nicolodi, Stefania Canova, Franca Moschiano, Domenico D'Amico, Susanna Usai, Gennaro Bussone, Giorgio Zanchin, Franco Granella, Susanna Russo and Giorgio Nider
    Citation: The Journal of Headache and Pain 2000 1(Suppl 1):0001S053.10194
    Content type: Published on:

    This article is part of a Supplement: Volume 1 Supplement 1

  42. A multicenter study was carried out in 10 Italian headache centers to investigate the prevalence of anxiety and depression in patients with chronic daily headache(CDH). The study investigated 219 patients (17...

    Authors: Rosanna Cerbo, Maria Pia Prudenzano, Piero Barbanti, Mariantonietta Savarese, Virgilio Gallai, Andrea Albert, Maria Nicolodi, Stefania Canova, Gennaro Bussone, Domenico D'Amico, Giuseppe Libro, Licia Grazzi, Franco Granella, Giorgio Zanchin, Giorgio Sandrini, Anna Pia Verri…
    Citation: The Journal of Headache and Pain 2000 1(Suppl 1):0001S045.10194
    Content type: Published on:

    This article is part of a Supplement: Volume 1 Supplement 1

  43. The identification of possible individual or/and environmental factors responsible for the chronic evolution of headache has represented a critical issue in recent years. The goal of this research was to enro...

    Authors: Francomichele Puca, Mario Guazzelli, Vittorio Sciruicchio, Giuseppe Libro, Paola Sarchielli, Susanna Russo, Andrea Alberti, Giorgio Zanchin, Cinzia Schianchi, Anna Pia Verri, Giuseppe Nappi, Rosanna Cerbo, Teresa Catarci, Giorgio Nider and Giuliano Relja
    Citation: The Journal of Headache and Pain 2000 1(Suppl 1):0001S033.10194
    Content type: Published on:

    This article is part of a Supplement: Volume 1 Supplement 1

  44. Chronic headache is often described but pooly understood regarding its mechanisms. We discuss the clinical presentation, differential diagnosis of chronic headache syndromes and treatment options. Patients pr...

    Authors: Maria Nicoladi and Federigo Sicuteri
    Citation: The Journal of Headache and Pain 2000 1(Suppl 1):0001S011.10194
    Content type: Published on:

    This article is part of a Supplement: Volume 1 Supplement 1

  45. The mechanisms facilitating or prompting the chronicization of headache and the increased use of analgesics are still unknown and under debate. It is not clear whether the daily use of analgesics in chronic h...

    Authors: Luigi Alberto Pini and Giuliano Relja
    Citation: The Journal of Headache and Pain 2000 1(Suppl 1):0001S021.10194
    Content type: Published on:

    This article is part of a Supplement: Volume 1 Supplement 1

  47. T lymphocytes participate not only in immune responses but also in the development of several pathologic reactions. Human T helper cells, on the basis of the cytokines they release, fall into two phenotypes, ...

    Authors: Alessandra Zicari, Giuseppe Stirparo, Cristina Rinaldi, Mario Giacovazzo, Stefania Morrone and Paolo Martelletti
    Citation: The Journal of Headache and Pain 2000 1(Suppl 2):0001S177.10194
    Content type: Published on:

    This article is part of a Supplement: Volume 1 Supplement 2

  48. Molecular analysis of TNFA alleles in Italian subjects affected by migraine was performed in order to define the involfement of HLA region genes in migraine. No statistically significant differences in TNFA a...

    Authors: Monica Poscente, Gloria Brioli, Patrizia Lulli, Marina Morellini, Paolo Martelletti, Mario Giacovazzo and Simonetta Trabace
    Citation: The Journal of Headache and Pain 2000 1(Suppl 2):0001S169.10194
    Content type: Published on:

    This article is part of a Supplement: Volume 1 Supplement 2

  49. Molecular genetics offers a novel approach to the understanding and management of migraine since the disorder is known to have a strong genetic component. In recent studies, polymorphisms in the genes for dop...

    Authors: Stephen J. Peroutka
    Citation: The Journal of Headache and Pain 2000 1(Suppl 2):0001S147.10194
    Content type: Published on:

    This article is part of a Supplement: Volume 1 Supplement 2

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