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Chronic paroxysmal hemicrania (CPH) is a rare headache syndrome resulting in non-remitting, recurrent, intense, short-lasting pain, with typical, often total, responsiveness to indomethacin. Other drugs have a...
We describe the headache characteristics of two patients with intracranial hypotension (IH) and correlate the magnetic resonance imaging (MRI) pattern to the clinical aspects of this type of headache. The firs...
The aim of the present study was to map the presence of neurotransmitters and nitric oxid synthase (NOS) in the trigeminal nucleus caudalis and cervical spinal cord of cat. Immunocytochemistry was used to map ...
Medication-overuse headaches are a relevant medical and social problem, for which specific treatments have not yet been defined. In patients with chronic daily headache who take analgesics every day, this head...
The purpose of this study was to determine the safety and efficacy of botulinum toxin type A (BOTOX; Allergan, Irvine, USA) in migraine prophylaxis. We performed a double-blind, randomized, 90-day placebo-cont...
Growing evidence suggests a possible relationship between migraine and thrombotic risk factors. The aim of this study was to analyze the possible relationship between migraine and acquired and genetic thrombop...
A multicenter one-year study was carried out on 6629 headache patients under 18 years of age, attending 27 centers and clinics devoted to headache in Italy to identify the prevalence of cluster headache (CH) i...
Nummular headache is characterized by mild to moderate, pressure-like head pain exclusively in a small, rounded or oval area without underlying structural lesions. Either during symptomatic periods or interict...
Chronic daily headache relates to the daily or almost daily occurrence of headache in a nonparoxysmal pattern. In this review, I discuss the presentation, development, outcome, and treatment of chronic daily h...
In the Vågå study of headache epidemiology, the “skinroll test” was carried out at the top (“arch”) of the shoulder girdle. For this purpose, a skin caliper (Servier, Leiden) was used. A total of 1796 parishio...
A preliminary, open label study was conducted on 20 patients with migraine without aura and with high headache frequency to assess the efficacy and tolerability of the new antiepileptic drug levetiracetam. Pat...
The aim of this study was to investigate the impact of the use of botulinum toxin type A (BoNT-A; BOTOX; Allergan, Inc.; Irvine, CA) as preventive treatment of chronic tension-type headache (CTH) on analgesic ...
The aim of this study was to determine postures adopted by patients during migraine attack. A total of 199 migraine patients were questioned about their postures during the migraine attack. Of these, 92 patien...
We audited the expectations of patients referred to a combined headache clinic from a specialist headache clinic and a pain relief unit due to the intractable nature of their headache. Our aim was to assess th...
Patients with chronic tension- type headache (CTTH) are the most difficult to treat. Tricyclic antidepressants are the first-line therapeutic agents, but their anticholinergic side effects limit their usage. S...
We performed a prevalence study to compare some lifestyle habits between subjects with migraine and those with nonmigraine primary headaches. We surveyed female students in randomly selected classes of the Sch...
Clinical studies suggest that hyperhomocysteinemia could be considered an independent risk factor for premature cerebral, peripheral and vascular diseases. A number of authors found an epidemiological correlat...
This article describes the mathematical process of building a model of migraine syndrome guided by research data and evidences. The paper illustrates the construction of a new possible model of the evolution, ...
Epidemiological genetic, family and twin studies show that the typical migraines carry a substantial genetic risk; they are currently conceptualized as complex genetic diseases. Several genetic association and...
If migraine or a migrainelike headache and stroke occur together, it is difficult to determine whether migraine is the cause of the stroke or stroke is the cause of symptomatic migraine. We report the case of...
Familial hemiplegic migraine (FHM) is a rare autosomal dominant-type migraine with aura. Attacks are characterised by hemiparesis in addition to other aura and migraine symptoms. Few studies have examined the...
We observed the occurrence of neuromuscular hyperexcitability, assessed with electromyographic ischemic tests, in headache patients in relation to Mg++ levels in serum, red blood cells and mononuclear cells. Cli...
We describe a series of experiments designed to investigate the mechanisms by which headaches can be triggered by red wine in a small minority of migraine patients. Some red wines are particularly potent rele...
The main goals of prophylactic treatment for migraine are to decrease headache attack frequency, length and intensity, to improve the efficacy of symptomatic drugs, to reduce their need, and to prevent pain c...
This last decade has seen remarkable progress made towards unraveling the mystery of primary headache disorders like migraine and cluster. The vascular theory has been superseded by recognition that neurovasc...
The role of daily analgesic use (also called abuse) in chronic daily headache (CDH) for the maintenance of chronic headache is discussed. The comprehension of the underlying mechanisms of actions is lacking m...
Triptans are presently a milestone in the treatment of migraine patients. Because of their effectiveness and safety, they have radically improved migraine treatment but their use has meant a substantial incre...
This article is part of a Supplement: Volume 4 Supplement 1
Headache represents not only an individual disease, but also an important pathology for society because its prevalence in the population is about 50.0%. Its physical, emotional, social and economic impacts ar...
This article is part of a Supplement: Volume 4 Supplement 1
The World Headache Alliance (WHA) works to reduce the burden of headache worldwide. Headache disorders are real, common and affect people of all ages, everywhere in the world. To reduce the burden resulting f...
This article is part of a Supplement: Volume 4 Supplement 1
Health services are rarely highly successful in meeting the needs of people with headache disorders, who everywhere are low in the priority queue. Taking the UK as an example within Europe, this paper briefly...
This article is part of a Supplement: Volume 4 Supplement 1
The major aim of the paper is to give an epidemiologist's viewpoint on several points related to the evaluation of the costs of migraine and to answer some questions that are important if one wishes to decrea...
This article is part of a Supplement: Volume 4 Supplement 1
The EuroMedicines Project created a single drug directory at a single time point (late 1998) to cover most of the member states of the European Union (EU) and some of the candidate states, so as to aid drug r...
This article is part of a Supplement: Volume 4 Supplement 1
The term “disease costing” applies to those economic appraisal methodologies that ascertain the cost borne by a community because of a disease. This approach has been used to calculate the social and economic...
This article is part of a Supplement: Volume 4 Supplement 1
Information on the prevalence and health burden of headache in Africa is scanty. Earlier studies in the 1970s suggested that migraine was a rare condition in the African. This may have been due to an underdia...
This article is part of a Supplement: Volume 4 Supplement 1
Migraine is associated with functional impairment. The migraine disability assessment (MIDAS) questionnaire is a scientific instrument which captures headache-related disability. The Italian version of MIDAS ...
This article is part of a Supplement: Volume 4 Supplement 1
Population-based studies have shown that migraineurs have reduced HRQoL independent of depression. Furthermore, HRQoL is reduced with increasing migraine attack frequency. In both population-based and clinic-...
This article is part of a Supplement: Volume 4 Supplement 1
Measuring population health is important to evaluate the impact of interventions, to monitor the changes in health status, and to predict the need for health care. A number of tools have been developed to mea...
This article is part of a Supplement: Volume 4 Supplement 1
Economic evaluation of health care programs or technologies requires distinguishing three types of costs: direct, indirect and human. The first two types do not imply peculiar methodological issues to quantif...
This article is part of a Supplement: Volume 4 Supplement 1
Comorbidity of migraine is important from a number of different perspectives. Co-occurrence of different diseases may complicate diagnosis as a high degree of symptomatic overlap may occur among conditions as...
This article is part of a Supplement: Volume 4 Supplement 1
One-year migraine prevalence rates in the general population for Western countries vary from 4% to 9% in men and from 11% to 25% in women. Non-Western countries report lower figures. Incidence rates for peopl...
This article is part of a Supplement: Volume 4 Supplement 1
This paper briefly describes some of the work developed by the World Health Organization in the field of health, disability and burden of diseases and how this work has relevant implications for migraine and,...
This article is part of a Supplement: Volume 4 Supplement 1
This article is part of a Supplement: Volume 4 Supplement 1
The Journal of Headache and Pain is the official journal of the European Headache Federation, Lifting The Burden, and the Asian Regional Consortium for Headache.
Citation Impact 2023
Journal Impact Factor: 7.3
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Source Normalized Impact per Paper (SNIP): 1.830
SCImago Journal Rank (SJR): 1.791
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