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  3. In phase one of the REALIZE study, zolmitriptan nasal spray demonstrated a significant headache response from 10 min post–dose and total symptom relief from 30 min post–dose. The objective of phase two was to ...

    Authors: M. Gawel, J. Aschoff, A. May and B. R. Charlesworth
    Citation: The Journal of Headache and Pain 2005 6:237
    Content type: Original Published on:

  4. Post–lumbar puncture headache is a frequent clinical problem. Needle design is expected to reduce post–puncture headache. In this study, we compared two different lumbar puncture needle designs in diagnostic l...

    Authors: L. Luostarinen, T. Heinonen, M. Luostarinen and A. Salmivaara
    Citation: The Journal of Headache and Pain 2005 6:235
    Content type: Original Published on:

  5. Chronic cluster headache remains refractory to medical therapy in at least 30% of those who suffer from this condition. The lack of alternative medical therapies that are as effective as, or more effective tha...

    Authors: P. A. Kowacs, E. J. Piovesan, R. W. G. R. de Campos, M. C. Lange, V. F. Zetola and L. C. Werneck
    Citation: The Journal of Headache and Pain 2005 6:234
    Content type: Brief Report Published on:

  8. In chronic migraine the central sensitisation and the changes of regional cerebral blood flow are mediated by nitric oxide (NO) and oxygen free radicals. Biofeedback is considered a preventive non–pharmacologi...

    Authors: I. Ciancarelli, M. G. Tozzi–Ciancarelli, C. Di Massimo, L. Olivieri and A. Carolei
    Citation: The Journal of Headache and Pain 2005 6:227
    Content type: PREVENTION OF CHRONIC HEADACHES Published on:

  9. Chronic migraine (CM) is an invalidating condition affecting a significant population of headache sufferers, frequently associated with medication overuse headache (MOH). Controlled trials and guidelines for t...

    Authors: M. Trucco, P. Meineri and L. Ruiz
    Citation: The Journal of Headache and Pain 2005 6:225
    Content type: PREVENTION OF CHRONIC HEADACHES Published on:

  10. Chronic migraine and transformed migraine are conditions with a progression from episodic to chronic headache, a disabling stage. During attack, cutaneous allodynia frequently occurs: it reflects sensitisation...

    Authors: M. Fanciullacci and F. De Cesaris
    Citation: The Journal of Headache and Pain 2005 6:224
    Content type: PREVENTION OF CHRONIC HEADACHES Published on:

  11. We conducted a study on 367 patients (86% female, 14% male; mean age 37±15 years) suffering from migraine with and without aura and chronic tension–type headache to evaluate the incidence of weight gain, an un...

    Authors: F. Maggioni, S. Ruffatti, F. Dainese, F. Mainardi and G. Zanchin
    Citation: The Journal of Headache and Pain 2005 6:221
    Content type: HEADACHE: THERAPEURIC CHOICES Published on:

  12. Sumatriptan is a selective agonist of 5HT1 (1B/1D) receptors, which has proved to be effective and safe for the acute treatment of migraine attacks. Nevertheless, its use by migraine sufferers is still limited...

    Authors: E. Sternieri, D. Pinetti, C. P. R. Coccia, S. Leone, A. Bertolini and A. Ferrari
    Citation: The Journal of Headache and Pain 2005 6:220
    Content type: HEADACHE: THERAPEURIC CHOICES Published on:

  13. The impact of migraine headaches is one of the major public health problems in several industrialised countries, with many patients reporting frequent and significant disability. Previous studies have assessed...

    Authors: R. Iannacchero, U. Cannistrà, A. La Vitola, F. Peltrone and E. De Caro
    Citation: The Journal of Headache and Pain 2005 6:218
    Content type: HEADACHE AND CONTINUITY IN HEALTH CARE Published on:

  14. The continuous care of headache patients, from headache centres to general practice, is a managerial problem that is still unsolved in Italy. In fact, if on the one hand patients do not usually go to headache ...

    Authors: G. B. La Pegna, F. Brighina, V. Saporito, A. Aloisio, C. Morreale and A. D’Agati
    Citation: The Journal of Headache and Pain 2005 6:217
    Content type: HEADACHE AND CONTINUITY IN HEALTH CARE Published on:

  15. Medication–overuse headache (MOH) is one of the headache forms that most frequently prompts patients to consult a specialist headache centre. The prevaence of this form in the general population is approximate...

    Authors: G. Sances, N. Ghiotto, M. Loi, E. Guaschino, E. Marchioni, T. Catarci and G. Nappi
    Citation: The Journal of Headache and Pain 2005 6:216
    Content type: HEADACHE AND CONTINUITY IN HEALTH CARE Published on:

  16. Migraine is a complex pathology and it should be regarded as a disease evolving during the lifetime along with other comorbid conditions. Migraine susceptibility may be unmasked by exogenous substances and the...

    Authors: M. G. Buzzi, D. Cologno and R. Formisano
    Citation: The Journal of Headache and Pain 2005 6:215
    Content type: HEADACHE AND CONTINUITY IN HEALTH CARE Published on:

  17. To evaluate the influence of psychometric variables on the “repeater” phenomenon in an emergency department, 15 “repeaters” and 27 outpatient migraineurs were recruited. All patients were submitted to the Beck...

    Authors: V. Villani, G. Bruti, C. Mostardini, F. Di Stani, L. Scattoni, D. Dugoni, N. Vanacore and R. Cerbo
    Citation: The Journal of Headache and Pain 2005 6:214
    Content type: HEADACHE IN THE EMERGENCY ROOM Published on:

  18. The objective was to study the demographics, diagnostic procedures and therapies employed in order to provide guidelines to Emergency Department (ED) physicians. A six–month retrospective analysis of the recor...

    Authors: G. Relja, A. Granato, F. Capozzoli, C. Maggiore, M. Catalan, G. Pizzolato, W. Zalukar, V. Livia, S. Gregorutti and M. Zorzon
    Citation: The Journal of Headache and Pain 2005 6:213
    Content type: HEADACHE IN THE EMERGENCY ROOM Published on:

  19. Although cluster headache (CH) is considered one of the most distinctive and painful primary headache disorders in clinical practice because of the brevity of each attack, its management is not always ergonomi...

    Authors: F. Di Sabato and M. Giacovazzo
    Citation: The Journal of Headache and Pain 2005 6:212
    Content type: HEADACHE IN THE EMERGENCY ROOM Published on:

  21. Headache is one of the most common reported complaints in the general adult population and it accounts for between 1% and 3% of admissions to an Emergency Department (ED). The overwhelming majority of patients...

    Authors: R. Cerbo, V. Villani, G. Bruti, F. Di Stani and C. Mostardini
    Citation: The Journal of Headache and Pain 2005 6:210
    Content type: HEADACHE IN THE EMERGENCY ROOM Published on:

  22. The prevalence and the clinical features of chronic daily headache (CDH) were studied in 968 children and adolescents observed during a period of one year in the Headache Centre of the Anna Meyer Paediatric Ho...

    Authors: C. Scalas and L. Calistri
    Citation: The Journal of Headache and Pain 2005 6:209
    Content type: HEADACHE IN CHILDHOOD AND ADOLESCENCE Published on:

  23. The onset of post-traumatic headache occurs frequently in children, where it is often caused by severe head injuries, therefore, it is part of a post–traumatic syndrome, rather than of an independent headache ...

    Authors: D. Moscato, M. I. Peracchi, G. Mazzotta, L. Savi and P. A. Battistella
    Citation: The Journal of Headache and Pain 2005 6:208
    Content type: HEADACHE IN CHILDHOOD AND ADOLESCENCE Published on:

  24. The aim of the study was to determine the frequency of clinical allodynia, osmophobia and red ear syndrome in a young population. Medical records of the children admitted for headache between 1 December 2004 a...

    Authors: V. Raieli, E. Pandolfi, M. La Vecchia, D. Puma, A. Calò, A. Celauro and D. Ragusa
    Citation: The Journal of Headache and Pain 2005 6:205
    Content type: HEADACHE IN CHILDHOOD AND ADOLESCENCE Published on:

  25. Several epidemiological studies have shown the presence of comorbidity between various types of sleep disorders and different headache subtypes. Migraine without aura is a sensitive risk factor for disorders o...

    Authors: M. Carotenuto, V. Guidetti, F. Ruju, F. Galli, F. R. Tagliente and A. Pascotto
    Citation: The Journal of Headache and Pain 2005 6:204
    Content type: HEADACHE IN CHILDHOOD AND ADOLESCENCE Published on:

  26. The Italian headache disorders website (www.cefalea.it) was launched in 1999 by the CIRNA foundation in partnership with Al.Ce, which is a lay association and member of the World Headache Alliance. In 2004, the w...

    Authors: P. Rossi, G. Sances and G. Nappi
    Citation: The Journal of Headache and Pain 2005 6:203
    Content type: HEADACHES, PHYSICIANS AND PATIENTS Published on:

  27. The social perception of headache, everywhere at low levels in industrialised countries, becomes totally absent in developing ones. Headache disorders came into the World Health Organization’s strategic priori...

    Authors: P. Martelletti, R. T. Haimanot, M. J. A. Lainez, A. M. Rapoport, K. Ravishankar, F. Sakai, S. D. Silberstein, M. Vincent and T. J. Steiner
    Citation: The Journal of Headache and Pain 2005 6:202
    Content type: HEADACHES, PHYSICIANS AND PATIENTS Published on:

  28. The internal working model on attachment dimensions changes with significant emotional experiences. The purpose of this study was to evaluate if and how the internal working models correlate with primary heada...

    Authors: L. Savi, R. Buccheri, A. Tambornini, P. De Martino, C. Albasi and L. Pinessi
    Citation: The Journal of Headache and Pain 2005 6:200
    Content type: PSYCHOBIOLOGICAL ASPECTS OF HEADACHES Published on:

  29. The purpose of this work was to investigate: (1) the differences in temperament and character between 49 women with migraine and 49 controls using the Temperament and Character Inventory (TCI), and (2) the ext...

    Authors: F. Mongini, S. Fassino, E. Rota, A. Deregibus, M. Levi, D. Monticone and G. Abbate–Daga
    Citation: The Journal of Headache and Pain 2005 6:198
    Content type: PSYCHOBIOLOGICAL ASPECTS OF HEADACHES Published on:

  30. Recent investigations documented that the prevalence of right–to–left shunt (RLS) in patients with migraine with aura (MA) is significantly higher than in healthy controls and similar to prevalence of RLS in y...

    Authors: N. Morelli, S. Gori, G. Cafforio, S. Gallerini, F. Baldacci, G. Orlandi and L. Murri
    Citation: The Journal of Headache and Pain 2005 6:197
    Content type: TACs AND CRANIAL NEURALAGIA Published on:

  31. In this study we compared systemic autonomic involvement in episodic cluster headache during active and silent periods. Seventeen patients were studied with sympathetic skin response, lying to standing test, V...

    Authors: Piero Meineri, Gianpaolo Pellegrino, Maria Gabriella Rosso and Enzo Grasso
    Citation: The Journal of Headache and Pain 2005 6:196
    Content type: TACS AND CRANIAL NEURALAGIA Published on:

  32. Trigeminal neuralgia is universally considered the neuropathic facial pain most and best known in medical practice. We propose a short review on trigeminal neuralgia reporting its main clinical aspects, unsolv...

    Authors: A. Truini, F. Galeotti and G. Cruccu
    Citation: The Journal of Headache and Pain 2005 6:195
    Content type: TACs AND CRANIAL NEURALAGIA Published on:

  33. Up to a few years ago, cluster headache (CH) was not thought to be an inherited disorder. However, several recent studies have suggested that genetic factors play a role in the disease. Genetic epidemiological...

    Authors: L. Pinessi, I. Rainero, C. Rivoiro, E. Rubino and S. Gallone
    Citation: The Journal of Headache and Pain 2005 6:194
    Content type: TACs AND CRANIAL NEURALAGIA Published on:

  34. The presence of significant and confounding psychiatric comorbidity is greater in patients attending headache clinics than in headache patients from the general population. The frequent comorbidity of headache...

    Authors: M. Savarese, M. Guazzelli, M. P. Prudenzano, M. Carnicelli, M. Rossi, V. Cardinali, S. Genco, P. Lamberti and P. Livrea
    Citation: The Journal of Headache and Pain 2005 6:193
    Content type: HEADACHE: CLINICAL AND COMORBIDITY ASPECTS Published on:

  35. To explore the relationship between the side of pain during attacks and psychopathological features in strictly unilateral migraine, we recruited 35 patients affected by migraine with and/or without aura diagn...

    Authors: D. Cologno, M. G. Buzzi, G. A. Carlesimo, P. Cicinelli, A. Costa, L. Fadda, R. Formisano, B. Marconi, S. Pero and C. Caltagirone
    Citation: The Journal of Headache and Pain 2005 6:192
    Content type: HEADACHE: CLINICAL AND COMORBIDITY ASPECTS Published on:

  36. Headache is a frequent feature of functional gastrointestinal disorders but there is no data on the responsible pathophysiological mechanism. The aim of this study was to verify whether alteration of post–pran...

    Authors: E. Pucci, M. Di Stefano, E. Miceli, G. R. Corazza, G. Sandrini and G. Nappi
    Citation: The Journal of Headache and Pain 2005 6:191
    Content type: HEADACHE: CLINICAL AND COMORBIDITY ASPECTS Published on:

  37. Literature data concerning the comorbidity of migraine and hypertension are conflicting and lacking in consistency [1–4]. This study was designed to evaluate the distribution of hypertension in a sample of mig...

    Authors: M. P. Prudenzano, C. Monetti, L. Merico, V. Cardinali, S. Genco, P. Lamberti and P. Livrea
    Citation: The Journal of Headache and Pain 2005 6:190
    Content type: HEADACHE: CLINICAL AND COMORBIDITY ASPECTS Published on:

  38. Migraine is a highly prevalent and disabling disease that is substantially undiagnosed in primary care. Recently, the ID Migraine, a self–administered questionnaire, was shown to be a valid and reliable screen...

    Authors: F. Brighina, G. Salemi, B. Fierro, A. Gasparro, G. Balletta, A. Aloisio, G. La Pegna, G. Randisi, V. Saporito, G. Calagna, F. Lanaia and R. Morana
    Citation: The Journal of Headache and Pain 2005 6:189
    Content type: ICHD-II EVALUATION AND PROPOSALS Published on:

  39. This study evaluates osmophobia (defined as an unpleasant perception, during a headache attack, of odours that are non–aversive or even pleasurable outside the attacks) in connection with the diagnosis of prim...

    Authors: G. Zanchin, F. Dainese, F. Mainardi, E. Mampreso, C. Perin and F. Maggioni
    Citation: The Journal of Headache and Pain 2005 6:188
    Content type: ICHD-II EVALUATION AND PROPOSALS Published on:

  41. Medication overuse headache (MOH) is a clinically important entity and it is now well documented that the regular use of acute symptomatic medication by people with migraine or tensiontype headache increases t...

    Authors: P. Calabresi and L. M. Cupini
    Citation: The Journal of Headache and Pain 2005 6:184
    Content type: PATHOPHYSIOLOGY OF HEADACHES Published on:

  42. A reduced habituation of averaged laser–evoked potential (LEP) amplitudes was previously found in migraine patients. The aim of the present study was to assess the habituation of single LEP responses and pain ...

    Authors: M. de Tommaso, G. Libro, M. Guido, L. Losito, P. Lamberti and P. Livrea
    Citation: The Journal of Headache and Pain 2005 6:183
    Content type: PATHOPHYSIOLOGY OF HEADACHES Published on:

  43. The study of CNS painmodulating pathways has led to important discoveries about the role of central nociceptive structures such as PAG and hypothalamus in the pathophysiology of episodic and chronic primary he...

    Authors: P. Rossi, M. Serrao, A. Perrotta, F. Pierelli, G. Sandrini and G. Nappi
    Citation: The Journal of Headache and Pain 2005 6:182
    Content type: PATHOPHYSIOLOGY OF HEADACHES Published on:

  44. We examined the distribution of HLA–DRB1 alleles in a cohort of 255 Italian migraine patients and in a control group of 325 healthy subjects. The frequency of DRB1*12 allele was found to be significantly reduced ...

    Authors: I. Rainero, E. Fasano, E. Rubino, C. Rivoiro, W. Valfrè, S. Gallone, L. Savi, S. Gentile, R. Lo Giudice, P. De Martino, A. M. Dall’Omo and L. Pinessi
    Citation: The Journal of Headache and Pain 2005 6:180
    Content type: Genetics Published on:

  45. In the present work, we report that the functional serotonin transporter gene promoter (5–HTTLPR) polymorphism is involved in migraine pathogenesis. The distribution of 5–HTTLPR genotypes was significantly dif...

    Authors: B. Borroni, C. Brambilla, P. Liberini, R. Rao, S. Archetti, S. Gipponi, G. Dalla Volta and A. Padovani
    Citation: The Journal of Headache and Pain 2005 6:179
    Content type: Genetics Published on:

  46. Numerous candidate genes for migraine have been proposed on the basis of their possible functional role in its pathogenesis. Genetic polymorphisms have been evaluated in association studies, some of which have...

    Authors: V. Lisi, G. Garbo, F. Miccichè, A. Stecca, S. Terrazzino, M. Franzoi, E. Tripoli, M. Clementi, A. Leon and P. A. Battistella
    Citation: The Journal of Headache and Pain 2005 6:178
    Content type: Genetics Published on:

  47. Chronic daily headache (CDH) is a heterogeneous group of headaches that includes primary and secondary varieties. Primary CDH is a frequent entity that probably affects 4–5% of the population. It can be subdiv...

    Authors: Miguel J. A. Láinez
    Citation: The Journal of Headache and Pain 2005 6:177
    Content type: KEY NOTE LECTURE Published on:

  48. Most women with migraine improve during pregnancy. Some women have their first attack. Migraine often recurs postpartum and can begin for the first time. Drugs are commonly used during pregnancy despite insuff...

    Authors: Stephen D. Silberstein
    Citation: The Journal of Headache and Pain 2005 6:176
    Content type: KEY NOTE LECTURE Published on:
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