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  1. Headache is one of the most common disorders in childhood, with an estimated 75% of children reporting significant headache by the age of 15 years. Pediatric migraine is the most frequent recurrent headache di...

    Authors: Fabio Antonaci, Cristina Voiticovschi-Iosob, Anna Luisia Di Stefano, Federica Galli, Aynur Ozge and Umberto Balottin
    Citation: The Journal of Headache and Pain 2014 15:15
    Content type: Review article Published on:

  2. Experimental animal models of migraine have suggested the existence of interactions between the endocannabinoid system and pain mediation in migraine. Extensive evidence has demonstrated a role for the cannabi...

    Authors: Rosaria Greco, Antonina Stefania Mangione, Giorgio Sandrini, Giuseppe Nappi and Cristina Tassorelli
    Citation: The Journal of Headache and Pain 2014 15:14
    Content type: Research article Published on:

  3. Thunderclap headache (TCH) is a sudden headache (SH) with accepted criteria of severe intensity and onset to peak within one minute. It is a well-known presentation for subarachnoid hemorrhage (SAH) but most p...

    Authors: Yu-Chen Cheng, Kuei-Hong Kuo and Tzu-Hsien Lai
    Citation: The Journal of Headache and Pain 2014 15:13
    Content type: Research article Published on:

  4. The purpose of this study was to evaluate the efficacy of a self-guided CD-ROM program (“Headstrong”) containing cognitive-behavioral self-management strategies versus an educational CD-ROM program for treatin...

    Authors: Michael A Rapoff, Mark Connelly, Jennifer L Bickel, Scott W Powers, Andrew D Hershey, Janelle R Allen, Cynthia W Karlson, Catrina C Litzenburg and John M Belmont
    Citation: The Journal of Headache and Pain 2014 15:12
    Content type: Research article Published on:

  5. Migraine is a disorder of central information processing which is characterized by a reduced habituation of event-related potentials. There might be positive effects of aerobic exercise on brain function and p...

    Authors: Claudia H Overath, Stephanie Darabaneanu, Marie C Evers, Wolf-Dieter Gerber, Melanie Graf, Armin Keller, Uwe Niederberger, Henrik Schäl, Michael Siniatchkin and Burkhard Weisser
    Citation: The Journal of Headache and Pain 2014 15:11
    Content type: Research article Published on:

  6. Medication-overuse headache (MOH) is caused by the regular use of medications to treat headache. There has been a lack of research into awareness of MOH. We distributed an electronic survey to undergraduate st...

    Authors: James TF Lai, John DC Dereix, Ravi P Ganepola, Peter G Nightingale, Kiera A Markey, Paul N Aveyard and Alexandra J Sinclair
    Citation: The Journal of Headache and Pain 2014 15:10
    Content type: Short report Published on:

  7. This is a reply letter to Letter to the ‘Editor Hemicrania continua: towards a new classification?’ Fabio Antonaci and Ottar Sjaastad The Journal of Headache and Pain Citation: 2014, 15:8.

    Authors: Peter J Goasdby
    Citation: The Journal of Headache and Pain 2014 15:9
    Content type: Letter to the Editor Published on:

    The Erratum to this article has been published in The Journal of Headache and Pain 2014 15:29

  8. Hemicrania continua (HC) was described and coined in 1984 by Sjaastad and Spierings. Later cases, carrying this appellation, should conform to the original description. The proposed classification criteria (IC...

    Authors: Fabio Antonaci and Ottar Sjaastad
    Citation: The Journal of Headache and Pain 2014 15:8
    Content type: Letter to the Editor Published on:

  9. CGRP is contained in a substantial proportion of unmyelinated trigeminal neurons innervating intracranial tissues. Previously, we have described a hemisected rodent scull preparation and later the intact trige...

    Authors: Charlotte Kageneck, Barbara E Nixdorf-Bergweiler, Karl Messlinger and Michael JM Fischer
    Citation: The Journal of Headache and Pain 2014 15:7
    Content type: Research article Published on:

  10. The quality of The Journal of Headache and Pain depends on the qualified and regular collaboration of renowned scientists, who devoted their time to constructively review the submitted articles.

    Authors: Valerio De Angelis
    Citation: The Journal of Headache and Pain 2014 15:4
    Content type: Reviewer Acknowledgement Published on:

  11. Migraine shows gender-specific incidence and has a higher prevalence in females. Gender plays an important role in the prevalence of migraine, but few studies have investigated the effect of gender on the cogn...

    Authors: Rongfei Wang, Zhao Dong, Xiaoyan Chen, Mingjie Zhang, Fan Yang, Xiaolan Zhang, Weiquan Jia and Shengyuan Yu
    Citation: The Journal of Headache and Pain 2014 15:6
    Content type: Research article Published on:

  12. The global burden of headache is very large, but knowledge of it is far from complete and needs still to be gathered. Published population-based studies have used variable methodology, which has influenced fin...

    Authors: Lars Jacob Stovner, Mohammed Al Jumah, Gretchen L Birbeck, Gopalakrishna Gururaj, Rigmor Jensen, Zaza Katsarava, Luiz Paulo Queiroz, Ann I Scher, Redda Tekle-Haimanot, Shuu-Jiun Wang and Timothy J Steiner
    Citation: The Journal of Headache and Pain 2014 15:5
    Content type: Consensus article Published on:

  13. The global burden of headache is very large, but knowledge of it is far from complete and needs still to be gathered. Published population-based studies have used variable methodology, which has influenced fin...

    Authors: Timothy J Steiner, Gopalakrishna Gururaj, Colette Andrée, Zaza Katsarava, Ilya Ayzenberg, Sheng-Yuan Yu, Mohammed Al Jumah, Redda Tekle-Haimanot, Gretchen L Birbeck, Arif Herekar, Mattias Linde, Edouard Mbewe, Kedar Manandhar, Ajay Risal, Rigmor Jensen, Luiz Paulo Queiroz…
    Citation: The Journal of Headache and Pain 2014 15:3
    Content type: Consensus article Published on:

  15. Religious belief can be used as a pain coping strategy. Our purpose was to evaluate the relationship between headache and religious activity using prospective data from a large population-based study.

    Authors: Erling Tronvik, Torgeir Sørensen, Mattias Linde, Lars Bendtsen, Ville Artto, Katarina Laurell, Mikko Kallela, John-Anker Zwart and Knut Hagen
    Citation: The Journal of Headache and Pain 2014 15:1
    Content type: Research article Published on:

  16. As major causes of global public ill-health and disability, headache disorders are paradoxically ignored in health policy and in planning, resourcing and implementing health services. This is true worldwide. R...

    Authors: Elena R Lebedeva, Jes Olesen, Vera V Osipova, Larisa I Volkova, Guzyal R Tabeeva and Timothy J Steiner
    Citation: The Journal of Headache and Pain 2013 14:101
    Content type: Methodology Published on:

  17. At present new daily persistent headache is just a group of conditions that are connected based on the temporal profile of their mode of onset. If new daily persistent headache is a true distinct syndrome like...

    Authors: Todd D Rozen and Jennifer L Beams
    Citation: The Journal of Headache and Pain 2013 14:100
    Content type: Case report Published on:

  18. Sport as a migraine trigger has been reported, but extensive information on these triggered attacks and the patients experiencing these attacks is lacking. Goal of this study was to investigate the lifetime pr...

    Authors: Hille Koppen and Peter LJ van Veldhoven
    Citation: The Journal of Headache and Pain 2013 14:99
    Content type: Research article Published on:

  19. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a rare hereditary small vascular disease and its mainly clinical manifestations are ischemic events. Spon...

    Authors: Lifei Lian, Dujuan Li, Zheng Xue, Qiming Liang, Feng Xu, Huicong Kang, Xiaoyan Liu and Suiqiang Zhu
    Citation: The Journal of Headache and Pain 2013 14:98
    Content type: Case report Published on:

  22. Transcutaneous supraorbital nerve stimulation (tSNS) with the Cefaly® device was recently found superior to sham stimulation for episodic migraine prevention in a randomized trial. Its safety and efficiency in...

    Authors: Delphine Magis, Simona Sava, Tullia Sasso d’Elia, Roberta Baschi and Jean Schoenen
    Citation: The Journal of Headache and Pain 2013 14:95
    Content type: Research article Published on:

  23. Autonomic imbalance may play an important role in the pathogenesis of reversible cerebral vasoconstriction syndromes (RCVS). This study aimed to assess the autonomic function by analyzing heart rate variabilit...

    Authors: Shih-Pin Chen, Albert C Yang, Jong-Ling Fuh and Shuu-Jiun Wang
    Citation: The Journal of Headache and Pain 2013 14:94
    Content type: Research article Published on:

  24. Calcitonin gene-related peptide (CGRP) and nitric oxide (NO) are regarded as key mediators in migraine and other primary headaches. Migraineurs respond to infusion of nitroglycerin with delayed headaches, and ...

    Authors: Stephan Feistel, Stephanie Albrecht and Karl Messlinger
    Citation: The Journal of Headache and Pain 2013 14:93
    Content type: Research article Published on:

  25. Botulinum toxin type A (BTX-A) has been reported to have analgesic effects independent of its action on muscle tone, mostly by acting on neurogenic inflammatory mediators and controlling the neurotransmitter r...

    Authors: Hatem S Shehata, Mohamed S El-Tamawy, Nevin M Shalaby and Gihan Ramzy
    Citation: The Journal of Headache and Pain 2013 14:92
    Content type: Research article Published on:

  27. The objectives of this study were; (1) to assess the prevalence and frequency of headache in patients referred to polysomnography (PSG) due to a clinical suspicion of obstructive sleep apnea (OSA) or another s...

    Authors: Kornelia Katalin Beiske, Michael Bjørn Russell and Knut Stavem
    Citation: The Journal of Headache and Pain 2013 14:90
    Content type: Research article Published on:

  28. Resting-state functional magnetic resonance imaging (RS-fMRI) has demonstrated disrupted default mode network (DMN) connectivity in a number of pain conditions, including migraine. However, the significance of...

    Authors: Alessandro Tessitore, Antonio Russo, Alfonso Giordano, Francesca Conte, Daniele Corbo, Manuela De Stefano, Sossio Cirillo, Mario Cirillo, Fabrizio Esposito and Gioacchino Tedeschi
    Citation: The Journal of Headache and Pain 2013 14:89
    Content type: Research article Published on:

  30. Population-based studies of headache disorders are important. They inform needs assessment and underpin service policy for a set of disorders that are a public-health priority. On the one hand, our knowledge o...

    Authors: Timothy J Steiner, Lars Jacob Stovner, Mohammed Al Jumah, Gretchen L Birbeck, Gopalakrishna Gururaj, Rigmor Jensen, Zaza Katsarava, Luiz Paulo Queiroz, Ann I Scher, Redda Tekle-Haimanot, Shuu-Jiun Wang, Paolo Martelletti, Tarun Dua and Somnath Chatterji
    Citation: The Journal of Headache and Pain 2013 14:87
    Content type: Consensus article Published on:

  31. The medical treatment of patients with chronic primary headache syndromes (chronic migraine, chronic tension-type headache, chronic cluster headache, hemicrania continua) is challenging as serious side effects...

    Authors: Paolo Martelletti, Rigmor H Jensen, Andrea Antal, Roberto Arcioni, Filippo Brighina, Marina de Tommaso, Angelo Franzini, Denys Fontaine, Max Heiland, Tim P Jürgens, Massimo Leone, Delphine Magis, Koen Paemeleire, Stefano Palmisani, Walter Paulus and Arne May
    Citation: The Journal of Headache and Pain 2013 14:86
    Content type: Consensus article Published on:

  32. Advanced neuroimaging approaches have been employed to prove that migraine was a central nervous system disorder. This study aims to examine resting-state abnormalities in migraine without aura (MWoA) patients...

    Authors: Ling Zhao, Jixin Liu, Xilin Dong, Yulin Peng, Kai Yuan, Fumei Wu, Jinbo Sun, Qiyong Gong, Wei Qin and Fanrong Liang
    Citation: The Journal of Headache and Pain 2013 14:85
    Content type: Research article Published on:

  33. Symptomatic cluster headache (CH) secondary to internal carotid artery dissection (ICAD) has been frequently reported, however, as far as we know, the coexistence of episodic CH and acute symptomatic CH second...

    Authors: Elisa Candeloro, Isabella Canavero, Maurizia Maurelli, Anna Cavallini, Natascia Ghiotto, Paolo Vitali and Giuseppe Micieli
    Citation: The Journal of Headache and Pain 2013 14:84
    Content type: Case report Published on:

  34. Red Ear Syndrome (RES) is a very rare disorder, with approximately 100 published cases in the medical literature. Red ear (RE) episodes are characterised by unilateral or bilateral attacks of paroxysmal burnin...

    Authors: Giorgio Lambru, Sarah Miller and Manjit S Matharu
    Citation: The Journal of Headache and Pain 2013 14:83
    Content type: Review article Published on:

  35. Socioeconomic status plays an important role in pain coping strategy. Its influence on migraine and tension-type headache may differ by gender. This study aimed to evaluate how socioeconomic status affects the...

    Authors: Min Kyung Chu, Dong-Wook Kim, Byung-Kun Kim, Jae-Moon Kim, Tae-Won Jang, Jeong Wook Park, Kwang Soo Lee and Soo-Jin Cho
    Citation: The Journal of Headache and Pain 2013 14:82
    Content type: Research article Published on:

  36. To validate a rapid questionnaire as a screening tool, because application of the diagnostic revised criteria of the ICHD-II for medication overuse headache (MOH) requires experience for the physician and is t...

    Authors: Virginie Dousset, Martial Maud, Mélanie Legoff, Françoise Radat, Bruno Brochet, Jean-François Dartigues and Tobias Kurth
    Citation: The Journal of Headache and Pain 2013 14:81
    Content type: Research article Published on:

  37. Numerous studies have indicated an increased risk of vascular disease among migraineurs. Alterations in endothelial and arterial function, which predispose to atherosclerosis and cardiovascular diseases, have ...

    Authors: Simona Sacco, Patrizia Ripa, Davide Grassi, Francesca Pistoia, Raffaele Ornello, Antonio Carolei and Tobias Kurth
    Citation: The Journal of Headache and Pain 2013 14:80
    Content type: Review article Published on:

  38. Headache is one of the most common neurological symptom reported in childhood and adolescence, leading to high levels of school absences and being associated with several comorbid conditions, particularly in n...

    Authors: Benedetta Bellini, Marco Arruda, Alessandra Cescut, Cosetta Saulle, Antonello Persico, Marco Carotenuto, Michela Gatta, Renata Nacinovich, Fausta Paola Piazza, Cristiano Termine, Elisabetta Tozzi, Franco Lucchese and Vincenzo Guidetti
    Citation: The Journal of Headache and Pain 2013 14:79
    Content type: Review article Published on:

  39. Migraine is a common neurological disorder of unclear pathogenesis. Recently incompetence of internal jugular vein valve (IJVVI) was found to be associated with some neurological conditions of unknown etiology...

    Authors: Izabela Domitrz, Grzegorz Styczynski, Justyna Wilczko, Lucja Gadomska, Beata Parzuchowska, Wojciech Domitrz and Anna Kaminska
    Citation: The Journal of Headache and Pain 2013 14:78
    Content type: Research article Published on:

  40. The high concordance rate of migraine in monozygotic twin pairs has long been recognised. In the current study, we present a monozygotic twin pair discordant for familial hemiplegic migraine (FHM).

    Authors: José Barros, Rui Barreto, Ana Filipa Brandão, Joana Domingos, Joana Damásio, Cristina Ramos, Carolina Lemos, Jorge Sequeiros, Isabel Alonso and José Pereira-Monteiro
    Citation: The Journal of Headache and Pain 2013 14:77
    Content type: Case report Published on:

  41. Episodic migraine is characterized by decreased high-frequency somatosensory oscillations (HFOs), reflecting thalamo-cortical activity, and deficient habituation of low-frequency (LF-) somatosensory evoked pot...

    Authors: Gianluca Coppola, Elisa Iacovelli, Martina Bracaglia, Mariano Serrao, Cherubino Di Lorenzo and Francesco Pierelli
    Citation: The Journal of Headache and Pain 2013 14:76
    Content type: Research article Published on:

  42. Studies suggest a higher prevalence of unfavourable cardiovascular risk factors amongst migraineurs, but results have been conflicting. The aim of this study was to investigate traditional and newly recognized...

    Authors: Fernanda Camboim Rockett, Alexandre da Silveira Perla, Ingrid D Schweigert Perry and Márcia L Fagundes Chaves
    Citation: The Journal of Headache and Pain 2013 14:75
    Content type: Research article Published on:

  43. Nitric oxide (NO) is thought to play an important role in the pathophysiology of migraine. Infusion of the nitrovasodilator glyceroltrinitrate (nitroglycerin, GTN), which mobilizes NO in the organism, is an ap...

    Authors: Kristin Seiler, Judith I Nusser, Jochen K Lennerz, Winfried L Neuhuber and Karl Messlinger
    Citation: The Journal of Headache and Pain 2013 14:74
    Content type: Research article Published on:

  44. Large geographical gaps in our knowledge of the prevalence and burden of headache disorders include Pakistan, a country with major problems of poverty, illiteracy and security. We report implementation in this...

    Authors: Arif D Herekar, Akbar A Herekar, Ali Ahmad, Umer L Uqaili, Bilal Ahmed, Jahanzeb Effendi, Syed Z Alvi and Timothy J Steiner
    Citation: The Journal of Headache and Pain 2013 14:73
    Content type: Research article Published on:

  45. Trigeminal neuralgia is a common disorder caused mainly by compression of the trigeminal nerve root by an overlying blood vessel. Pharmacotherapy and surgery are ineffective or unsuitable in many patients. The...

    Authors: Yong Hu, Xiaofei Guan, Lin Fan, Mu Li, Yiteng Liao, Zhiyu Nie and Lingjing Jin
    Citation: The Journal of Headache and Pain 2013 14:72
    Content type: Review article Published on:

  46. Ever since their identification, interest in the role of transient receptor potential (TRP) channels in health and disease has steadily increased. Robust evidence has underlined the role of TRP channels expres...

    Authors: Silvia Benemei, Francesco De Cesaris, Camilla Fusi, Eleonora Rossi, Chiara Lupi and Pierangelo Geppetti
    Citation: The Journal of Headache and Pain 2013 14:71
    Content type: Review article Published on:

  47. Multiple sclerosis (MS) is a chronic autoimmune disease that targets myelinated axons in the central nervous system. Headache has been reported as a subtle symptom of the onset of MS, with a variable frequency...

    Authors: Guan-Yu Lin, Chih-Wei Wang, Tsung-Ta Chiang, Giia-Sheun Peng and Fu-Chi Yang
    Citation: The Journal of Headache and Pain 2013 14:70
    Content type: Case report Published on:

  48. Recently, an increasing number of articles have appeared on central auditory processing disorders, but in the literature there is only one study that evaluated the possible correlation between migraine in the ...

    Authors: Antonella Ciriaco, Angelo Russo, Daniele Monzani, Elisabetta Genovese, Paola Benincasa, Ernesto Caffo and Luigi Alberto Pini
    Citation: The Journal of Headache and Pain 2013 14:69
    Content type: Research article Published on:

  49. The mechanisms associating sleep and migraine are unknown. No previous polysomnographic (PSG) or pain-threshold (PT) study has compared patients with sleep-related migraine attacks (SM), non-sleep related migr...

    Authors: Morten Engstrøm, Knut Hagen, Marte Bjørk, Gøril Bruvik Gravdahl and Trond Sand
    Citation: The Journal of Headache and Pain 2013 14:68
    Content type: Research article Published on:

  50. A retrospective review of patients treated with Occipital Nerve Stimulation (ONS) at two large tertiary referral centres has been audited in order to optimise future treatment pathways.

    Authors: Stefano Palmisani, Adnan Al-Kaisy, Roberto Arcioni, Tom Smith, Andrea Negro, Giorgio Lambru, Vijay Bandikatla, Eleanor Carson and Paolo Martelletti
    Citation: The Journal of Headache and Pain 2013 14:67
    Content type: Research article Published on:
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