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  1. Animal models have provided a growing body of information about the pathophysiology of headaches and novel therapeutic targets. In recent years, experiments in awake animals have gained attention as more relev...

    Authors: Doga Vuralli, Anne-Sophie Wattiez, Andrew F. Russo and Hayrunnisa Bolay
    Citation: The Journal of Headache and Pain 2019 20:11
    Content type: Review article Published on:

  2. OnabotulinumtoxinA is effective in treating chronic migraine (CM), but there are limited data assessing how allodynia affects preventive treatment responses. This subanalysis of the 108-week, multicenter, open...

    Authors: William B. Young, J. Ivan Lopez, John F. Rothrock, Amelia Orejudos, Aubrey Manack Adams, Richard B. Lipton and Andrew M. Blumenfeld
    Citation: The Journal of Headache and Pain 2019 20:10
    Content type: Research article Published on:

  4. Research in migraine points towards central-peripheral complexity with a widespread pattern of structures involved. Migraine-associated neck and shoulder muscle pain has clinically been conceptualized as myofa...

    Authors: Nico Sollmann, Nina Mathonia, Dominik Weidlich, Michaela Bonfert, Sebastian A. Schroeder, Katharina A. Badura, Tabea Renner, Florian Trepte-Freisleder, Carl Ganter, Sandro M. Krieg, Claus Zimmer, Ernst J. Rummeny, Dimitrios C. Karampinos, Thomas Baum, Mirjam N. Landgraf and Florian Heinen
    Citation: The Journal of Headache and Pain 2019 20:8
    Content type: Research article Published on:

  5. The present study aimed to preliminary explore the abnormal neuromagnetic activation in female migraine patients between attacks using magnetoencephalography (MEG) and pattern reversed visual evoked magnetic f...

    Authors: Zhi Y. Zhou, Yan W. Yu, Di Wu, Hong X. Liu, Jing Xiang, Ting Wu, Qi Q. Chen and Xiao S. Wang
    Citation: The Journal of Headache and Pain 2019 20:7
    Content type: Research article Published on:

  6. Monoclonal antibodies acting on the calcitonin gene-related peptide or on its receptor are new drugs to prevent migraine. Four monoclonal antibodies have been developed: one targeting the calcitonin gene-relat...

    Authors: Simona Sacco, Lars Bendtsen, Messoud Ashina, Uwe Reuter, Gisela Terwindt, Dimos-Dimitrios Mitsikostas and Paolo Martelletti
    Citation: The Journal of Headache and Pain 2019 20:6
    Content type: Consensus article Published on:

    The Correction to this article has been published in The Journal of Headache and Pain 2019 20:58

  7. Recent technical advances in genetics made large-scale genome-wide association studies (GWAS) in migraine feasible and have identified over 40 common DNA sequence variants that affect risk for migraine types. ...

    Authors: Arn M. J. M. van den Maagdenberg, Dale R. Nyholt and Verneri Anttila
    Citation: The Journal of Headache and Pain 2019 20:5
    Content type: Review article Published on:

  8. Migraine-related intracerebral white matter lesions (WMLs) are likely to be microvascular in nature and can be found in all hemispheric lobes. The aim of this study was to investigate migraine patients with or wi...

    Authors: Hedvig Komáromy, Mingchen He, Gábor Perlaki, Gergely Orsi, Szilvia Anett Nagy, Edit Bosnyák, David Kamson Olayinka, Flóra John, Anita Trauninger and Zoltán Pfund
    Citation: The Journal of Headache and Pain 2019 20:4
    Content type: Research article Published on:

  9. Although altered neural networks have been demonstrated in recent MEG (magnetoencephalography) research in migraine patients during resting state, it is unknown whether this alteration can be detected in task-...

    Authors: Jing Ren, Jing Xiang, Yueqiu Chen, Feng Li, Ting Wu and Jingping Shi
    Citation: The Journal of Headache and Pain 2019 20:3
    Content type: Research article Published on:

  10. For a trial of supportive self-management for people with chronic headache we needed to develop and validate a telephone classification interview that can be used by a non-headache specialist to classify commo...

    Authors: Rachel Potter, Siew Wan Hee, Frances Griffiths, Katherine Dodd, Eleanor Hoverd, Martin Underwood and Manjit Matharu
    Citation: The Journal of Headache and Pain 2019 20:2
    Content type: Research article Published on:

  11. Following publication of the original article [1], the authors notified us that a part of the Figure 3 legend was omitted during proofing stage.

    Authors: Licia Grazzi, Cristina Tassorelli, Marina de Tommaso, Giulia Pierangeli, Paolo Martelletti, Innocenzo Rainero, Pierangelo Geppetti, Anna Ambrosini, Paola Sarchielli, Eric Liebler and Piero Barbanti
    Citation: The Journal of Headache and Pain 2019 20:1
    Content type: Correction Published on:

    The original article was published in The Journal of Headache and Pain 2018 19:98

  12. Maintenance of effect following treatment with galcanezumab compared to placebo in adult patients with episodic or chronic migraine was evaluated.

    Authors: Stefanie Förderreuther, Qi Zhang, Virginia L. Stauffer, Sheena K. Aurora and Miguel J. A. Láinez
    Citation: The Journal of Headache and Pain 2018 19:121
    Content type: Research article Published on:

  13. Following publication of the original article [1], the authors notified us o that the Table 1 citation within the legend was not presented as initially requested.

    Authors: Paolo Martelletti, Piero Barbanti, Licia Grazzi, Giulia Pierangeli, Innocenzo Rainero, Pierangelo Geppetti, Anna Ambrosini, Paola Sarchielli, Cristina Tassorelli, Eric Liebler and Marina de Tommaso
    Citation: The Journal of Headache and Pain 2018 19:120
    Content type: Correction Published on:

    The original article was published in The Journal of Headache and Pain 2018 19:101

  14. After publication of this supplement [1], it was brought to our attention that e-mail errors were apparent in the following abstracts. This has now been included in this correction.

    Authors:
    Citation: The Journal of Headache and Pain 2018 19:119
    Content type: Correction Published on:

    The original article was published in The Journal of Headache and Pain 2018 19:80

  15. Traditional Medicine (TM) is widely accepted to be used for the treatment headache disorders in Kuwait however, researches remain poorly documented. We aimed to study the frequency of TM use and its impact in ...

    Authors: Jasem Y. Al-Hashel, Samar Farouk Ahmed, Fatemah J Alshawaf and Raed Alroughani
    Citation: The Journal of Headache and Pain 2018 19:118
    Content type: Research Published on:

  16. The three primary headaches, tension-type headache, migraine and cluster headache, occur in both genders, but all seem to have a sex-specific prevalence. These gender differences suggest that both male and fem...

    Authors: Zoë Delaruelle, Tatiana A. Ivanova, Sabrina Khan, Andrea Negro, Raffaele Ornello, Bianca Raffaelli, Alberto Terrin, Dimos D. Mitsikostas and Uwe Reuter
    Citation: The Journal of Headache and Pain 2018 19:117
    Content type: Review article Published on:

  17. Headache disorders are an important global public-health problem, but under-diagnosed, undertreated and under-prioritized. Deficiencies in health care for headache, present everywhere, are likely to be greater...

    Authors: Kedar Manandhar, Ajay Risal, Mattias Linde and Timothy J. Steiner
    Citation: The Journal of Headache and Pain 2018 19:116
    Content type: Research article Published on:

  18. Migraine is associated with many debilitating symptoms that affect daily functioning. My Migraine Voice is a large global cross-sectional study aimed at understanding the full burden and impact of migraine direct...

    Authors: Paolo Martelletti, Todd J. Schwedt, Michel Lanteri-Minet, Rebeca Quintana, Veruska Carboni, Hans-Christoph Diener, Elena Ruiz de la Torre, Audrey Craven, Annette Vangaa Rasmussen, Simon Evans, Annik K. Laflamme, Rachel Fink, Donna Walsh, Paula Dumas and Pamela Vo
    Citation: The Journal of Headache and Pain 2018 19:115
    Content type: Research article Published on:

  19. Evidence supports the use of non-invasive vagus nerve stimulation (nVNS; gammaCore®) as a promising therapeutic option for patients with cluster headache (CH). We conducted this audit of real-world data from p...

    Authors: Juana Marin, Nicola Giffin, Elizabeth Consiglio, Candace McClure, Eric Liebler and Brendan Davies
    Citation: The Journal of Headache and Pain 2018 19:114
    Content type: Research article Published on:

  20. Our aim was 1) to reduce disability, as characterized by headache frequency, duration and severity in patients with post-traumatic headache (PTHA), 2) to reduce the number of medical boards and work limitation...

    Authors: Virginia B. Baker, Kathryn M. Eliasen and Nawaz K. Hack
    Citation: The Journal of Headache and Pain 2018 19:113
    Content type: Research article Published on:

  21. Post-concussion syndrome (PCS) is defined as the presence of 3 or more of the following signs and symptoms after experiencing head injury such as headache, dizziness, fatigue, irritability, insomnia, difficult...

    Authors: Asres Bedaso, Ephrem Geja, Mohammed Ayalew, Zewdie Oltaye and Bereket Duko
    Citation: The Journal of Headache and Pain 2018 19:112
    Content type: Research article Published on:

  22. Several studies examined headaches as a symptom of brain neoplasms. Nevertheless, very few studies attempted to specifically evaluate the role of headaches as a risk factor. This study aimed to investigate the...

    Authors: Chao-Hung Chen, Jau-Jiuan Sheu, Yi-Chun Lin and Herng-Ching Lin
    Citation: The Journal of Headache and Pain 2018 19:111
    Content type: Research article Published on:

  23. There has been tremendous change on neuropathic pain research in the past 20 years in China and around the world. We analyzed the global trend of neuropathic pain research and compared China’s quantity and qua...

    Authors: Jishi Ye, Huang Ding, Juan Ren and Zhongyuan Xia
    Citation: The Journal of Headache and Pain 2018 19:110
    Content type: Research article Published on:

  24. Cognitive dysfunction has recently gained attention as a significant problem among migraine sufferers. All of the clinical studies show poor cognitive performance during migraine attacks, though, the intericta...

    Authors: Doga Vuralli, Cenk Ayata and Hayrunnisa Bolay
    Citation: The Journal of Headache and Pain 2018 19:109
    Content type: Review article Published on:

  25. This multicentric survey investigates the prevalence and characteristics of Airplane Headache in children affected by primary headaches.

    Authors: Debora De Carlo, Irene Toldo, Agnese Maria Tamborino, Barbara Bolzonella, Maria Giuseppina Ledda, Lucia Margari, Vincenzo Raieli, Margherita Santucci, Vittorio Sciruicchio, Angelo Vecchio, Sergio Zanini, Stefano Sartori, Michela Gatta, Alberto Verrotti and Pier Antonio Battistella
    Citation: The Journal of Headache and Pain 2018 19:108
    Content type: Research article Published on:

  26. Perampanel is a novel antiepileptic drug acting via non-competitive antagonism on glutamatergic AMPA receptors, and the subsequent inhibition of ion calcium influx. Since it was recently postulated that the an...

    Authors: Giuseppe Tringali, Diego Currò and Pierluigi Navarra
    Citation: The Journal of Headache and Pain 2018 19:107
    Content type: Research article Published on:

  27. Despite its high prevalence, migraine remains underdiagnosed and undertreated. ID-Migraine is a short, self-administrated questionnaire, originally developed in English by Lipton et al. and later validated in ...

    Authors: Éva Csépány, Marianna Tóth, Tamás Gyüre, Máté Magyar, György Bozsik, Dániel Bereczki, Gabriella Juhász and Csaba Ertsey
    Citation: The Journal of Headache and Pain 2018 19:106
    Content type: Research article Published on:

  28. Migraine prevention with erenumab and migraine induction by calcitonin gene-related peptide (CGRP) both carry notable individual variance. We wanted to explore a possible association between individual efficac...

    Authors: Casper Emil Christensen, Samaira Younis, Marie Deen, Sabrina Khan, Hashmat Ghanizada and Messoud Ashina
    Citation: The Journal of Headache and Pain 2018 19:105
    Content type: Research article Published on:

  29. In migraine patients with cervical myofascial trigger points whose target areas coincide with migraine sites (M + cTrPs), TrP anesthetic injection reduces migraine symptoms, but the procedure often causes disc...

    Authors: Giannapia Affaitati, Raffaele Costantini, Claudio Tana, Domenico Lapenna, Cosima Schiavone, Francesco Cipollone and Maria Adele Giamberardino
    Citation: The Journal of Headache and Pain 2018 19:104
    Content type: Research article Published on:

  30. Better tools are required for the earlier identification and management of orofacial pain with different aetiologies. The painDETECT questionnaire is a patient-completed screening tool with utility for identif...

    Authors: Daniyal J Jafree, Joanna M Zakrzewska, Saumya Bhatia and Carolina Venda Nova
    Citation: The Journal of Headache and Pain 2018 19:103
    Content type: Research article Published on:

  31. Although the mechanism of chronic migraine (CM) is unclear, it might be related to central sensitization and neuronal persistent hyperexcitability. The tyrosine phosphorylation of NR2B (NR2B-pTyr) reportedly c...

    Authors: Xue-Ying Wang, Hui-Ru Zhou, Sha Wang, Chao-Yang Liu, Guang-Cheng Qin, Qing-Qing Fu, Ji-Ying Zhou and Li-Xue Chen
    Citation: The Journal of Headache and Pain 2018 19:102
    Content type: Research article Published on:

  32. Non-invasive vagus nerve stimulation (nVNS) has been shown to be practical, safe, and well tolerated for treating primary headache disorders. The recent multicenter, randomized, double-blind, sham-controlled P...

    Authors: Paolo Martelletti, Piero Barbanti, Licia Grazzi, Giulia Pierangeli, Innocenzo Rainero, Pierangelo Geppetti, Anna Ambrosini, Paola Sarchielli, Cristina Tassorelli, Eric Liebler and Marina de Tommaso
    Citation: The Journal of Headache and Pain 2018 19:101
    Content type: Research article Published on:

    The Correction to this article has been published in The Journal of Headache and Pain 2018 19:120

  33. Cluster headache is a severe headache disorder with unknown aetiology. The pathophysiology and symptoms present certain common features with migraine. Specifically, activation of the trigeminal vascular system...

    Authors: Caroline Ran, Carmen Fourier, Margret Zinnegger, Anna Steinberg, Christina Sjöstrand, Elisabet Waldenlind and Andrea Carmine Belin
    Citation: The Journal of Headache and Pain 2018 19:100
    Content type: Research article Published on:

  34. To enrich the hitherto insufficient understanding regarding the mechanisms of action of transcranial direct current stimulation (tDCS) in pain disorders, we investigated its modulating effects on cerebral pain...

    Authors: Steffen Naegel, Josephine Biermann, Nina Theysohn, Christoph Kleinschnitz, Hans-Christoph Diener, Zaza Katsarava, Mark Obermann and Dagny Holle
    Citation: The Journal of Headache and Pain 2018 19:99
    Content type: Research article Published on:

  35. The PRESTO study of non-invasive vagus nerve stimulation (nVNS; gammaCore®) featured key primary and secondary end points recommended by the International Headache Society to provide Class I evidence that for ...

    Authors: Licia Grazzi, Cristina Tassorelli, Marina de Tommaso, Giulia Pierangeli, Paolo Martelletti, Innocenzo Rainero, Pierangelo Geppetti, Anna Ambrosini, Paola Sarchielli, Eric Liebler and Piero Barbanti
    Citation: The Journal of Headache and Pain 2018 19:98
    Content type: Research article Published on:

    The Correction to this article has been published in The Journal of Headache and Pain 2019 20:1

  36. Menstrual migraine (MM) and premenstrual syndrome (PMS) are two conditions linked to specific phases of the menstrual cycle. The exact pathophysiological mechanisms are not fully understood, but both condition...

    Authors: Kjersti Grøtta Vetvik, E. Anne MacGregor, Christofer Lundqvist and Michael Bjørn Russell
    Citation: The Journal of Headache and Pain 2018 19:97
    Content type: Short report Published on:

  37. Headache is one of the most common disabling medical condition affecting over 40% of adults globally. Many patients with headache prefer to alleviate their symptom with a range of over-the-counter analgesics t...

    Authors: Adeladlew Kassie Netere, Daniel Asfaw Erku, Ashenafi Kibret Sendekie, Eyob Alemayehu Gebreyohannes, Niguse Yigzaw Muluneh and Sewunet Admasu Belachew
    Citation: The Journal of Headache and Pain 2018 19:96
    Content type: Research article Published on:

  38. Until now, headache disorders have not been established as a risk factor for dementia. The aim of this study was to determine whether headache was associated with an increased risk of dementia.

    Authors: Jing Wang, Weihao Xu, Shasha Sun, Shengyuan Yu and Li Fan
    Citation: The Journal of Headache and Pain 2018 19:95
    Content type: Research article Published on:

  39. Cluster headache attacks can, in many patients, be successfully treated with oxygen via a non-rebreather mask. In previous studies oxygen at flow rates of both 7 L/min and 12 L/min was shown to be effective. T...

    Authors: Thijs H. T. Dirkx, Danielle Y. P. Haane and Peter J. Koehler
    Citation: The Journal of Headache and Pain 2018 19:94
    Content type: Research article Published on:

  40. Idiopathic Intracranial Hypertension (IIH) is characterized by an elevation of intracranial pressure (ICP no identifiable cause. The aetiology remains largely unknown, however observations made in a number of ...

    Authors: Jan Hoffmann, Susan P Mollan, Koen Paemeleire, Christian Lampl, Rigmor H Jensen and Alexandra J Sinclair
    Citation: The Journal of Headache and Pain 2018 19:93
    Content type: Consensus article Published on:

  41. Subcutaneous erenumab reduced monthly migraine days and increased the likelihood of achieving a ≥ 50% reduction at all monthly assessment points tested in 2 pivotal trials in episodic migraine (EM) and chronic...

    Authors: Todd Schwedt, Uwe Reuter, Stewart Tepper, Messoud Ashina, David Kudrow, Gregor Broessner, Guy P. Boudreau, Peter McAllister, Thuy Vu, Feng Zhang, Sunfa Cheng, Hernan Picard, Shihua Wen, Joseph Kahn, Jan Klatt and Daniel Mikol
    Citation: The Journal of Headache and Pain 2018 19:92
    Content type: Research article Published on:

  42. OnabotulinumtoxinA is being increasingly used in the management of chronic migraine (CM). Treatment with onabotulinumtoxinA poses challenges compared with traditional therapy with orally administered preventat...

    Authors: Lars Bendtsen, Simona Sacco, Messoud Ashina, Dimos Mitsikostas, Fayyaz Ahmed, Patricia Pozo-Rosich and Paolo Martelletti
    Citation: The Journal of Headache and Pain 2018 19:91
    Content type: Consensus article Published on:

  43. Primary headache are prevalent and debilitating disorders. Acute pain cessation is one of the key points in their treatment. Many drugs have been studied but the design of the trials is not usually homogeneous...

    Authors: D. García-Azorin, N. Yamani, L. M. Messina, I. Peeters, M. Ferrili, D. Ovchinnikov, M. L. Speranza, V. Marini, A. Negro, S. Benemei and M. Barloese
    Citation: The Journal of Headache and Pain 2018 19:90
    Content type: Research article Published on:

    The Correction to this article has been published in The Journal of Headache and Pain 2019 20:14

  44. Although clinically distinguishable, migraine and cluster headache share prominent features such as unilateral pain, common pharmacological triggers such glyceryl trinitrate, histamine, calcitonin gene-related...

    Authors: Anne Luise Vollesen, Silvia Benemei, Francesca Cortese, Alejandro Labastida-Ramírez, Francesca Marchese, Lanfranco Pellesi, Michele Romoli, Messoud Ashina and Christian Lampl
    Citation: The Journal of Headache and Pain 2018 19:89
    Content type: Review Published on:

  45. Since children and adolescents are frequently experiencing emotional and behavioral consequences due to pain, their parents should be aware of this emotional and behavioral status. Therefore, the aim of this s...

    Authors: Amal Al-Khotani, Mattias Gjelset, Aron Naimi-Akbar, Britt Hedenberg-Magnusson, Malin Ernberg and Nikolaos Christidis
    Citation: The Journal of Headache and Pain 2018 19:88
    Content type: Research article Published on:

  47. Evidence on whether the therapeutic effect and good safety profile of onabotulinumtoxinA (Botox®) in chronic migraine (CM) patients is maintained over long term treatment is still limited. We herein aimed at a...

    Authors: Michail Vikelis, Andreas A. Argyriou, Emmanouil V. Dermitzakis, Konstantinos C. Spingos, Nikolaos Makris and Evangelia Kararizou
    Citation: The Journal of Headache and Pain 2018 19:87
    Content type: Research article Published on:

  48. Insomnia and migraine are closely related; insomnia aggravates migraine symptoms. This study was conducted to investigate the impact of migraine on the clinical presentation of insomnia symptoms.

    Authors: Jiyoung Kim, Soo-Jin Cho, Won-Joo Kim, Kwang Ik Yang, Chang-Ho Yun and Min Kyung Chu
    Citation: The Journal of Headache and Pain 2018 19:86
    Content type: Research article Published on:

  49. There is an unmet need of pharmacological and non-pharmacological treatment options for migraine patients. Exercise can be used in the treatment of several pain conditions, including. However, what exact role ...

    Authors: Faisal Mohammad Amin, Stavroula Aristeidou, Carlo Baraldi, Ewa K. Czapinska-Ciepiela, Daponte D. Ariadni, Davide Di Lenola, Cherilyn Fenech, Konstantinos Kampouris, Giorgos Karagiorgis, Mark Braschinsky and Mattias Linde
    Citation: The Journal of Headache and Pain 2018 19:83
    Content type: Review article Published on:

  50. Following the publication of this article [1], the authors noticed that they incorrectly reported the Absolute risk of ischemic stroke in women aged 20 to 44 years in relation to the use of hormonal contracept...

    Authors: Simona Sacco, Gabriele S. Merki-Feld, Karen Lehrmann Ægidius, Johannes Bitzer, Marianne Canonico, Tobias Kurth, Christian Lampl, Øjvind Lidegaard, E. Anne MacGregor, Antoinette MaassenVanDenBrink, Dimos-Dimitrios Mitsikostas, Rossella Elena Nappi, George Ntaios, Per Morten Sandset and Paolo Martelletti
    Citation: The Journal of Headache and Pain 2018 19:81
    Content type: Correction Published on:

    The original article was published in The Journal of Headache and Pain 2017 18:108

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