High prevalence of right to left shunt in women with chronic migraine
The Journal of Headache and Pain volume 14, Article number: P105 (2013)
To study the prevalence of right to left shunt in a series of women with CM.
This series includes 51 women (age 44 years, range 16-63) meeting diagnostic criteria (IHC-II revised 2006)for CM. There were only 5 women with migraine with aura attacks. We carried out a transcranial doppler study (AplioXG, model SSA-790A, Toshiba) following the CODICIA study protocol .
Thirty patients (58.8%) showed some degree of right to left shunt. Three (60%) out of the 5 patients with migraine with aura had shunt. Thirteen patients (43%, 25 of total series) had hits during normal breathing and 17 (58%, 33% of the total series) during Valsalva maneuver. Shunt was massive in 10 patients (33%, 20% of the total series); in 9 of them shunt became massive only during the Valsalva maneuver.
Prevalence of right to left shunt in women with CM is higher than expected for the general population (1). The clinical implications of our findings need to be determined, though they suggest a relationship between the presence of shunt with an increased frequency of migraine attacks.
Diener HC, et al.: . Current Opin Neurol 2007, 20: 310–319. 10.1097/WCO.0b013e328136c22d
Nahas SJ, et al.: . Cephalalgia 2010, 30: 535–542.
Serena J, et al.: . Stroke 2008, 39: 3131–3136. 10.1161/STROKEAHA.108.521427
Support by FISSS grant PI11/00899 (ISCIII)
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Larrosa, D., Benavente, L., Calleja, S. et al. High prevalence of right to left shunt in women with chronic migraine. J Headache Pain 14 (Suppl 1), P105 (2013). https://doi.org/10.1186/1129-2377-14-S1-P105
- Public Health
- Internal Medicine
- General Population
- Study Protocol