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  1. Content type: Correction

    After publication of this supplement [1], it was brought to our attention that e-mail errors were apparent in the following abstracts. This has now been included in this correction.

    Authors:

    Citation: The Journal of Headache and Pain 2018 19:119

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    The original article was published in The Journal of Headache and Pain 2018 19:80

  2. Content type: Research

    Traditional Medicine (TM) is widely accepted to be used for the treatment headache disorders in Kuwait however, researches remain poorly documented. We aimed to study the frequency of TM use and its impact in ...

    Authors: Jasem Y. Al-Hashel, Samar Farouk Ahmed, Fatemah J Alshawaf and Raed Alroughani

    Citation: The Journal of Headache and Pain 2018 19:118

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  3. Content type: Review article

    The three primary headaches, tension-type headache, migraine and cluster headache, occur in both genders, but all seem to have a sex-specific prevalence. These gender differences suggest that both male and fem...

    Authors: Zoë Delaruelle, Tatiana A. Ivanova, Sabrina Khan, Andrea Negro, Raffaele Ornello, Bianca Raffaelli, Alberto Terrin, Dimos D. Mitsikostas and Uwe Reuter

    Citation: The Journal of Headache and Pain 2018 19:117

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  4. Content type: Research article

    Headache disorders are an important global public-health problem, but under-diagnosed, undertreated and under-prioritized. Deficiencies in health care for headache, present everywhere, are likely to be greater...

    Authors: Kedar Manandhar, Ajay Risal, Mattias Linde and Timothy J. Steiner

    Citation: The Journal of Headache and Pain 2018 19:116

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  5. Content type: Research article

    Migraine is associated with many debilitating symptoms that affect daily functioning. My Migraine Voice is a large global cross-sectional study aimed at understanding the full burden and impact of migraine direct...

    Authors: Paolo Martelletti, Todd J. Schwedt, Michel Lanteri-Minet, Rebeca Quintana, Veruska Carboni, Hans-Christoph Diener, Elena Ruiz de la Torre, Audrey Craven, Annette Vangaa Rasmussen, Simon Evans, Annik K. Laflamme, Rachel Fink, Donna Walsh, Paula Dumas and Pamela Vo

    Citation: The Journal of Headache and Pain 2018 19:115

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  6. Content type: Research article

    Evidence supports the use of non-invasive vagus nerve stimulation (nVNS; gammaCore®) as a promising therapeutic option for patients with cluster headache (CH). We conducted this audit of real-world data from p...

    Authors: Juana Marin, Nicola Giffin, Elizabeth Consiglio, Candace McClure, Eric Liebler and Brendan Davies

    Citation: The Journal of Headache and Pain 2018 19:114

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  7. Content type: Research article

    Our aim was 1) to reduce disability, as characterized by headache frequency, duration and severity in patients with post-traumatic headache (PTHA), 2) to reduce the number of medical boards and work limitation...

    Authors: Virginia B. Baker, Kathryn M. Eliasen and Nawaz K. Hack

    Citation: The Journal of Headache and Pain 2018 19:113

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  8. Content type: Research article

    Post-concussion syndrome (PCS) is defined as the presence of 3 or more of the following signs and symptoms after experiencing head injury such as headache, dizziness, fatigue, irritability, insomnia, difficult...

    Authors: Asres Bedaso, Ephrem Geja, Mohammed Ayalew, Zewdie Oltaye and Bereket Duko

    Citation: The Journal of Headache and Pain 2018 19:112

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  9. Content type: Review article

    Cognitive dysfunction has recently gained attention as a significant problem among migraine sufferers. All of the clinical studies show poor cognitive performance during migraine attacks, though, the intericta...

    Authors: Doga Vuralli, Cenk Ayata and Hayrunnisa Bolay

    Citation: The Journal of Headache and Pain 2018 19:109

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  10. Content type: Research article

    Several studies examined headaches as a symptom of brain neoplasms. Nevertheless, very few studies attempted to specifically evaluate the role of headaches as a risk factor. This study aimed to investigate the...

    Authors: Chao-Hung Chen, Jau-Jiuan Sheu, Yi-Chun Lin and Herng-Ching Lin

    Citation: The Journal of Headache and Pain 2018 19:111

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  11. Content type: Research article

    There has been tremendous change on neuropathic pain research in the past 20 years in China and around the world. We analyzed the global trend of neuropathic pain research and compared China’s quantity and qua...

    Authors: Jishi Ye, Huang Ding, Juan Ren and Zhongyuan Xia

    Citation: The Journal of Headache and Pain 2018 19:110

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  12. Content type: Research article

    This multicentric survey investigates the prevalence and characteristics of Airplane Headache in children affected by primary headaches.

    Authors: Debora De Carlo, Irene Toldo, Agnese Maria Tamborino, Barbara Bolzonella, Maria Giuseppina Ledda, Lucia Margari, Vincenzo Raieli, Margherita Santucci, Vittorio Sciruicchio, Angelo Vecchio, Sergio Zanini, Stefano Sartori, Michela Gatta, Alberto Verrotti and Pier Antonio Battistella

    Citation: The Journal of Headache and Pain 2018 19:108

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  13. Content type: Research article

    Despite its high prevalence, migraine remains underdiagnosed and undertreated. ID-Migraine is a short, self-administrated questionnaire, originally developed in English by Lipton et al. and later validated in ...

    Authors: Éva Csépány, Marianna Tóth, Tamás Gyüre, Máté Magyar, György Bozsik, Dániel Bereczki, Gabriella Juhász and Csaba Ertsey

    Citation: The Journal of Headache and Pain 2018 19:106

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  14. Content type: Research article

    Perampanel is a novel antiepileptic drug acting via non-competitive antagonism on glutamatergic AMPA receptors, and the subsequent inhibition of ion calcium influx. Since it was recently postulated that the an...

    Authors: Giuseppe Tringali, Diego Currò and Pierluigi Navarra

    Citation: The Journal of Headache and Pain 2018 19:107

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  15. Content type: Research article

    In migraine patients with cervical myofascial trigger points whose target areas coincide with migraine sites (M + cTrPs), TrP anesthetic injection reduces migraine symptoms, but the procedure often causes disc...

    Authors: Giannapia Affaitati, Raffaele Costantini, Claudio Tana, Domenico Lapenna, Cosima Schiavone, Francesco Cipollone and Maria Adele Giamberardino

    Citation: The Journal of Headache and Pain 2018 19:104

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  16. Content type: Research article

    Migraine prevention with erenumab and migraine induction by calcitonin gene-related peptide (CGRP) both carry notable individual variance. We wanted to explore a possible association between individual efficac...

    Authors: Casper Emil Christensen, Samaira Younis, Marie Deen, Sabrina Khan, Hashmat Ghanizada and Messoud Ashina

    Citation: The Journal of Headache and Pain 2018 19:105

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  17. Content type: Research article

    Although the mechanism of chronic migraine (CM) is unclear, it might be related to central sensitization and neuronal persistent hyperexcitability. The tyrosine phosphorylation of NR2B (NR2B-pTyr) reportedly c...

    Authors: Xue-Ying Wang, Hui-Ru Zhou, Sha Wang, Chao-Yang Liu, Guang-Cheng Qin, Qing-Qing Fu, Ji-Ying Zhou and Li-Xue Chen

    Citation: The Journal of Headache and Pain 2018 19:102

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  18. Content type: Research article

    Better tools are required for the earlier identification and management of orofacial pain with different aetiologies. The painDETECT questionnaire is a patient-completed screening tool with utility for identif...

    Authors: Daniyal J Jafree, Joanna M Zakrzewska, Saumya Bhatia and Carolina Venda Nova

    Citation: The Journal of Headache and Pain 2018 19:103

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  19. Content type: Research article

    Non-invasive vagus nerve stimulation (nVNS) has been shown to be practical, safe, and well tolerated for treating primary headache disorders. The recent multicenter, randomized, double-blind, sham-controlled P...

    Authors: Paolo Martelletti, Piero Barbanti, Licia Grazzi, Giulia Pierangeli, Innocenzo Rainero, Pierangelo Geppetti, Anna Ambrosini, Paola Sarchielli, Cristina Tassorelli, Eric Liebler and Marina de Tommaso

    Citation: The Journal of Headache and Pain 2018 19:101

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  20. Content type: Research article

    Cluster headache is a severe headache disorder with unknown aetiology. The pathophysiology and symptoms present certain common features with migraine. Specifically, activation of the trigeminal vascular system...

    Authors: Caroline Ran, Carmen Fourier, Margret Zinnegger, Anna Steinberg, Christina Sjöstrand, Elisabet Waldenlind and Andrea Carmine Belin

    Citation: The Journal of Headache and Pain 2018 19:100

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  21. Content type: Research article

    To enrich the hitherto insufficient understanding regarding the mechanisms of action of transcranial direct current stimulation (tDCS) in pain disorders, we investigated its modulating effects on cerebral pain...

    Authors: Steffen Naegel, Josephine Biermann, Nina Theysohn, Christoph Kleinschnitz, Hans-Christoph Diener, Zaza Katsarava, Mark Obermann and Dagny Holle

    Citation: The Journal of Headache and Pain 2018 19:99

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  22. Content type: Research article

    The PRESTO study of non-invasive vagus nerve stimulation (nVNS; gammaCore®) featured key primary and secondary end points recommended by the International Headache Society to provide Class I evidence that for ...

    Authors: Licia Grazzi, Cristina Tassorelli, Marina de Tommaso, Giulia Pierangeli, Paolo Martelletti, Innocenzo Rainero, Pierangelo Geppetti, Anna Ambrosini, Paola Sarchielli, Eric Liebler and Piero Barbanti

    Citation: The Journal of Headache and Pain 2018 19:98

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  23. Content type: Short report

    Menstrual migraine (MM) and premenstrual syndrome (PMS) are two conditions linked to specific phases of the menstrual cycle. The exact pathophysiological mechanisms are not fully understood, but both condition...

    Authors: Kjersti Grøtta Vetvik, E. Anne MacGregor, Christofer Lundqvist and Michael Bjørn Russell

    Citation: The Journal of Headache and Pain 2018 19:97

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  24. Content type: Research article

    Headache is one of the most common disabling medical condition affecting over 40% of adults globally. Many patients with headache prefer to alleviate their symptom with a range of over-the-counter analgesics t...

    Authors: Adeladlew Kassie Netere, Daniel Asfaw Erku, Ashenafi Kibret Sendekie, Eyob Alemayehu Gebreyohannes, Niguse Yigzaw Muluneh and Sewunet Admasu Belachew

    Citation: The Journal of Headache and Pain 2018 19:96

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  25. Content type: Research article

    Until now, headache disorders have not been established as a risk factor for dementia. The aim of this study was to determine whether headache was associated with an increased risk of dementia.

    Authors: Jing Wang, Weihao Xu, Shasha Sun, Shengyuan Yu and Li Fan

    Citation: The Journal of Headache and Pain 2018 19:95

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  26. Content type: Research article

    Cluster headache attacks can, in many patients, be successfully treated with oxygen via a non-rebreather mask. In previous studies oxygen at flow rates of both 7 L/min and 12 L/min was shown to be effective. T...

    Authors: Thijs H. T. Dirkx, Danielle Y. P. Haane and Peter J. Koehler

    Citation: The Journal of Headache and Pain 2018 19:94

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  27. Content type: Consensus article

    Idiopathic Intracranial Hypertension (IIH) is characterized by an elevation of intracranial pressure (ICP no identifiable cause. The aetiology remains largely unknown, however observations made in a number of ...

    Authors: Jan Hoffmann, Susan P Mollan, Koen Paemeleire, Christian Lampl, Rigmor H Jensen and Alexandra J Sinclair

    Citation: The Journal of Headache and Pain 2018 19:93

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  28. Content type: Research article

    Subcutaneous erenumab reduced monthly migraine days and increased the likelihood of achieving a ≥ 50% reduction at all monthly assessment points tested in 2 pivotal trials in episodic migraine (EM) and chronic...

    Authors: Todd Schwedt, Uwe Reuter, Stewart Tepper, Messoud Ashina, David Kudrow, Gregor Broessner, Guy P. Boudreau, Peter McAllister, Thuy Vu, Feng Zhang, Sunfa Cheng, Hernan Picard, Shihua Wen, Joseph Kahn, Jan Klatt and Daniel Mikol

    Citation: The Journal of Headache and Pain 2018 19:92

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  29. Content type: Consensus article

    OnabotulinumtoxinA is being increasingly used in the management of chronic migraine (CM). Treatment with onabotulinumtoxinA poses challenges compared with traditional therapy with orally administered preventat...

    Authors: Lars Bendtsen, Simona Sacco, Messoud Ashina, Dimos Mitsikostas, Fayyaz Ahmed, Patricia Pozo-Rosich and Paolo Martelletti

    Citation: The Journal of Headache and Pain 2018 19:91

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  30. Content type: Research article

    Primary headache are prevalent and debilitating disorders. Acute pain cessation is one of the key points in their treatment. Many drugs have been studied but the design of the trials is not usually homogeneous...

    Authors: D. García-Azorin, N. Yamani, L. M. Messina, I. Peeters, M. Ferrili, D. Ovchinnikov, M. L. Speranza, V. Marini, A. Negro, S. Benemei and M. Barloese

    Citation: The Journal of Headache and Pain 2018 19:90

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  31. Content type: Review

    Although clinically distinguishable, migraine and cluster headache share prominent features such as unilateral pain, common pharmacological triggers such glyceryl trinitrate, histamine, calcitonin gene-related...

    Authors: Anne Luise Vollesen, Silvia Benemei, Francesca Cortese, Alejandro Labastida-Ramírez, Francesca Marchese, Lanfranco Pellesi, Michele Romoli, Messoud Ashina and Christian Lampl

    Citation: The Journal of Headache and Pain 2018 19:89

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  32. Content type: Research article

    Since children and adolescents are frequently experiencing emotional and behavioral consequences due to pain, their parents should be aware of this emotional and behavioral status. Therefore, the aim of this s...

    Authors: Amal Al-Khotani, Mattias Gjelset, Aron Naimi-Akbar, Britt Hedenberg-Magnusson, Malin Ernberg and Nikolaos Christidis

    Citation: The Journal of Headache and Pain 2018 19:88

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  33. Content type: Research article

    Evidence on whether the therapeutic effect and good safety profile of onabotulinumtoxinA (Botox®) in chronic migraine (CM) patients is maintained over long term treatment is still limited. We herein aimed at a...

    Authors: Michail Vikelis, Andreas A. Argyriou, Emmanouil V. Dermitzakis, Konstantinos C. Spingos, Nikolaos Makris and Evangelia Kararizou

    Citation: The Journal of Headache and Pain 2018 19:87

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  34. Content type: Research article

    Insomnia and migraine are closely related; insomnia aggravates migraine symptoms. This study was conducted to investigate the impact of migraine on the clinical presentation of insomnia symptoms.

    Authors: Jiyoung Kim, Soo-Jin Cho, Won-Joo Kim, Kwang Ik Yang, Chang-Ho Yun and Min Kyung Chu

    Citation: The Journal of Headache and Pain 2018 19:86

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  35. Content type: Research article

    The degree to which work-related difficulties are recognized in headache research is poor and often carried out with inadequate information such as “reduced ability to work as usual”, which do not capture at a...

    Authors: Alberto Raggi, Venusia Covelli, Erika Guastafierro, Matilde Leonardi, Chiara Scaratti, Licia Grazzi, Marco Bartolini, Giovanna Viticchi, Sabina Cevoli, Giulia Pierangeli, Gioacchino Tedeschi, Antonio Russo, Piero Barbanti, Cinzia Aurilia, Carlo Lovati, Luca Giani…

    Citation: The Journal of Headache and Pain 2018 19:85

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  36. Content type: Research article

    Migraine is a distinct neurological disease that imposes a significant burden on patients, society, and the healthcare system. This study aimed to characterize the incremental burden of migraine in individuals...

    Authors: Pamela Vo, Juanzhi Fang, Aikaterini Bilitou, Annik K. Laflamme and Shaloo Gupta

    Citation: The Journal of Headache and Pain 2018 19:82

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  37. Content type: Review article

    A myofascial trigger point is defined as a hyperirritable spot in skeletal muscle that is associated with a hypersensitive palpable nodule in a taut band. It has been suggested that myofascial trigger points t...

    Authors: Thien Phu Do, Gerda Ferja Heldarskard, Lærke Tørring Kolding, Jeppe Hvedstrup and Henrik Winther Schytz

    Citation: The Journal of Headache and Pain 2018 19:84

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  38. Content type: Review article

    There is an unmet need of pharmacological and non-pharmacological treatment options for migraine patients. Exercise can be used in the treatment of several pain conditions, including. However, what exact role ...

    Authors: Faisal Mohammad Amin, Stavroula Aristeidou, Carlo Baraldi, Ewa K. Czapinska-Ciepiela, Daponte D. Ariadni, Davide Di Lenola, Cherilyn Fenech, Konstantinos Kampouris, Giorgos Karagiorgis, Mark Braschinsky and Mattias Linde

    Citation: The Journal of Headache and Pain 2018 19:83

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  39. Content type: Correction

    Following the publication of this article [1], the authors noticed that they incorrectly reported the Absolute risk of ischemic stroke in women aged 20 to 44 years in relation to the use of hormonal contracept...

    Authors: Simona Sacco, Gabriele S. Merki-Feld, Karen Lehrmann Ægidius, Johannes Bitzer, Marianne Canonico, Tobias Kurth, Christian Lampl, Øjvind Lidegaard, E. Anne MacGregor, Antoinette MaassenVanDenBrink, Dimos-Dimitrios Mitsikostas, Rossella Elena Nappi, George Ntaios, Per Morten Sandset and Paolo Martelletti

    Citation: The Journal of Headache and Pain 2018 19:81

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    The original article was published in The Journal of Headache and Pain 2017 18:108

  40. Content type: Research article

    Cluster headaches (CH) are recurrent severe headaches, which impose a major burden on the life of patients. We investigated the impact of CH on employment status and job burden.

    Authors: Yun-Ju Choi, Byung-Kun Kim, Pil-Wook Chung, Mi Ji Lee, Jung-Wook Park, Min Kyung Chu, Jin-Young Ahn, Byung-Su Kim, Tae-Jin Song, Jong-Hee Sohn, Kyungmi Oh, Kwang-Soo Lee, Soo-Kyoung Kim, Kwang-Yeol Park, Jae Myun Chung, Heui-Soo Moon…

    Citation: The Journal of Headache and Pain 2018 19:78

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  41. Content type: Consensus article

    We systematically reviewed data about the effect of exogenous estrogens and progestogens on the course of migraine during reproductive age. Thereafter a consensus procedure among international experts was unde...

    Authors: Simona Sacco, Gabriele S. Merki-Feld, Karen Lehrmann Ægidius, Johannes Bitzer, Marianne Canonico, Andreas R. Gantenbein, Tobias Kurth, Christian Lampl, Øjvind Lidegaard, E. Anne MacGregor, Antoinette MaassenVanDenBrink, Dimos-Dimitrios Mitsikostas, Rossella Elena Nappi, George Ntaios, Koen Paemeleire, Per Morten Sandset…

    Citation: The Journal of Headache and Pain 2018 19:76

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  42. Content type: Short report

    There is limited literature on prolonged aura (PA - defined as an aura including at least one symptom for > 1 h and < 7d), and there are no prospective studies.

    Authors: Michele Viana, Grazia Sances, Mattias Linde, Giuseppe Nappi, Farihah Khaliq, Peter J. Goadsby and Cristina Tassorelli

    Citation: The Journal of Headache and Pain 2018 19:77

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  43. Content type: Research article

    Limited histopathology studies have suggested that reversible cerebral vasoconstriction syndromes (RCVS) does not present with vascular wall inflammation. Previous vascular imaging studies have had inconsisten...

    Authors: Chun-Yu Chen, Shih-Pin Chen, Jong-Ling Fuh, Jiing-Feng Lirng, Feng-Chi Chang, Yen-Feng Wang and Shuu-Jiun Wang

    Citation: The Journal of Headache and Pain 2018 19:74

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  44. Content type: Research article

    Familial hemiplegic migraine type 1 (FHM1) is a form of migraine with aura caused by heterozygous mutations in 4 genes: CACNA1A, ATP1A2, SNC1A and PRRT2, but further heterogeneity is expected. Here have been desc...

    Authors: G. S. Grieco, S. Gagliardi, I. Ricca, O. Pansarasa, M. Neri, F. Gualandi, G. Nappi, A. Ferlini and C. Cereda

    Citation: The Journal of Headache and Pain 2018 19:75

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  45. Content type: Research article

    Therapeutic management of Chronic Migraine (CM), often associated with Medication Overuse Headache (MOH), is chiefly empirical, as no biomarker predicting or correlating with clinical efficacy is available to ...

    Authors: Alessandro Viganò, Maria Claudia Torrieri, Massimiliano Toscano, Francesca Puledda, Barbara Petolicchio, Tullia Sasso D’Elia, Angela Verzina, Sonia Ruggiero, Marta Altieri, Edoardo Vicenzini, Jean Schoenen and Vittorio Di Piero

    Citation: The Journal of Headache and Pain 2018 19:73

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  46. Content type: Research article

    Percutaneous occipital nerve stimulation (ONS) is effective in refractory chronic cluster headache (rCCH) patients. Responders to ONS differ from non-responders by greater glucose metabolism in subgenual anter...

    Authors: Delphine Magis, Kevin D’Ostilio, Marco Lisicki, Chany Lee and Jean Schoenen

    Citation: The Journal of Headache and Pain 2018 19:72

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  47. Content type: Research article

    DFN-11, a 3 mg sumatriptan subcutaneous (SC) autoinjector for acute treatment of migraine, has not been assessed previously in multiple attacks. The objective of this study was to evaluate the efficacy, tolera...

    Authors: Stephen Landy, Sagar Munjal, Elimor Brand-Schieber and Alan M. Rapoport

    Citation: The Journal of Headache and Pain 2018 19:70

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