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  1. Medication-overuse headache (MOH) is often comorbid with emotional disturbances, contributing to poorer outcomes. The aims of the present study were to assess the psychometric properties of the Stagnation Scal...

    Authors: Marco Innamorati, Maurizio Pompili, Denise Erbuto, Federica Ricci, Monica Migliorati, Dorian A Lamis, Mario Amore, Paolo Girardi and Paolo Martelletti
    Citation: The Journal of Headache and Pain 2015 16:2
    Content type: Research article Published on:

  2. Evidence of the cost and effects of interventions for reducing the global burden of migraine remains scarce. Our objective was to estimate the population-level cost-effectiveness of evidence-based migraine int...

    Authors: Mattias Linde, Timothy J Steiner and Dan Chisholm
    Citation: The Journal of Headache and Pain 2015 16:15
    Content type: Research article Published on:

  3. Certain environmental stimuli are frequently reported as typical triggers of migraine pain. Whether these so-called triggers are independent precipitators of migraine pain or mere symptoms of the premonitory p...

    Authors: Laura H Schulte, Tim P Jürgens and Arne May
    Citation: The Journal of Headache and Pain 2015 16:14
    Content type: Research article Published on:

  5. Trigeminal autonomic cephalalgias are primary headaches characterized by unilateral pain and cranial autonomic symptoms. However, associated autonomic symptoms have also been reported in other headaches and fa...

    Authors: Sabrina Khan, Ida Wibrandt, Per Rochat and Messoud Ashina
    Citation: The Journal of Headache and Pain 2015 16:12
    Content type: Case report Published on:

  6. Migraine and Tension-type headache (TTH) are common and disabling primary headache disorders. They are more prevalent in females. The second to fourth digit ratio (2D:4D) is sexually dimorphic in humans and is...

    Authors: Wei Xie, Mianwang He, Ruozhuo Liu, Zhao Dong, Jingdan Xie, Dan Wang and Shengyuan Yu
    Citation: The Journal of Headache and Pain 2015 16:11
    Content type: Research article Published on:

  7. Cryotherapy is the most common non-pharmacological pain-relieving method. The aim of this pilot study was to ascertain whether intranasal evaporative cooling may be an effective intervention in an acute migrai...

    Authors: Jitka Vanderpol, Barbara Bishop, Manjit Matharu and Mark Glencorse
    Citation: The Journal of Headache and Pain 2015 16:5
    Content type: Research article Published on:

  9. Evaluation of the prevalence and impact of headache on the preceding day (“headache yesterday”; HY) is a new approach, allowing more precise estimation of headache-attributed burden without recall error. The a...

    Authors: Ilya Ayzenberg, Zaza Katsarava, Asya Sborowski, Mark Obermann, Michail Chernysh, Vera Osipova, Guzelya Tabeeva and Timothy J Steiner
    Citation: The Journal of Headache and Pain 2015 16:7
    Content type: Research article Published on:

  10. A comparison has been made between the cervicogenic headache criteria in the new IHS classification of headaches (3rd edition- beta version) and The Cervicogenic Headache International Study Group’s (GHISG) crite...

    Authors: Torbjørn A Fredriksen, Fabio Antonaci and Ottar Sjaastad
    Citation: The Journal of Headache and Pain 2015 16:6
    Content type: Commentary Published on:

  11. The comorbidity of headache and psychiatric symptoms is a well-recognized clinical phenomenon, but there are only limited data regarding the temporal relationship between headache and symptoms of anxiety and d...

    Authors: Brit A Blaauw, Grete Dyb, Knut Hagen, Turid L Holmen, Mattias Linde, Tore Wentzel-Larsen and John-Anker Zwart
    Citation: The Journal of Headache and Pain 2015 16:10
    Content type: Research article Published on:

  12. Migraine is a common headache disorder that may be associated with vascular disease and cerebral white matter hyperintensities (WMHs) on magnetic resonance imaging (MRI) scan. High sensitivity C-reactive prote...

    Authors: Aynur Yilmaz Avci, Hatice Lakadamyali, Serap Arikan, Ulku Sibel Benli and Munire Kilinc
    Citation: The Journal of Headache and Pain 2015 16:9
    Content type: Research article Published on:

  13. Epidemiological data on the prevalence of headache in nursing staff in Mainland China are lacking. We therefore performed a study to assess the prevalence of headache, and factors associated with headaches, in...

    Authors: Yan Wang, Jingdan Xie, Fei Yang, Shiwen Wu, Hebo Wang, Xiaolan Zhang, Hua Liu, Xin Deng and Shengyuan Yu
    Citation: The Journal of Headache and Pain 2015 16:4
    Content type: Research article Published on:

  15. Chronic myalgia is associated with higher muscle levels of certain algesic biomarkers. The aim of this study was to investigate if hypertonic saline-induced jaw myalgia also leads to release of such biomarkers...

    Authors: Sofia Louca, Nikolaos Christidis, Bijar Ghafouri, Björn Gerdle, Peter Svensson, Thomas List and Malin Ernberg
    Citation: The Journal of Headache and Pain 2014 15:89
    Content type: Research article Published on:

  16. Medication overuse headache (MOH) is a very heterogeneous disorder for which a recommended treatment is not yet available. The purpose of this study was to investigate any possible roles of demographic and cli...

    Authors: Stefano Caproni, Elisa Bianchi, Letizia M Cupini, Ilenia Corbelli, Ettore Beghi, Paolo Calabresi and Paola Sarchielli
    Citation: The Journal of Headache and Pain 2014 15:88
    Content type: Short report Published on:

  17. Complex migraine aura in teenagers can be complicated to diagnose. The aim of this study was to present detailed features of migraine aura in teenage migraineurs.

    Authors: Igor Petrusic, Vera Pavlovski, Dragana Vucinic and Jasna Jancic
    Citation: The Journal of Headache and Pain 2014 15:87
    Content type: Research article Published on:

  18. Burden of headache has been assessed in adults in countries worldwide, and is high, but data for children and adolescents are sparse. The objectives of this study were o develop a questionnaire and methodology...

    Authors: Çiçek Wöber-Bingöl, Christian Wöber, Derya Uluduz, Uğur Uygunoğlu, Tuna Stefan Aslan, Martin Kernmayer, Heidi-Elisabeth Zesch, Nancy TA Gerges, Gudrun Wagner, Aksel Siva and Timothy J Steiner
    Citation: The Journal of Headache and Pain 2014 15:86
    Content type: Research article Published on:

  19. Triptans, serotonin 5-HT1B/1D receptor agonists, exert their action by targeting serotonin 5-HT1B/1D receptors, are used for treatment of migraine attack. Presently, 5 different triptans, namely sumatriptan, zolm...

    Authors: Kentaro Tokuoka, Risa Takayanagi, Yuji Suzuki, Masayuki Watanabe, Yasuhisa Kitagawa and Yasuhiko Yamada
    Citation: The Journal of Headache and Pain 2014 15:85
    Content type: Research article Published on:

  20. Nausea is a common and disabling symptom of migraine. The origin of nausea is not well understood although functional connections between trigeminal neurons and the nucleus tractus solitarius may explain occur...

    Authors: Farooq H Maniyar, Till Sprenger, Christoph Schankin and Peter J Goadsby
    Citation: The Journal of Headache and Pain 2014 15:84
    Content type: Research article Published on:

  21. Altered cortical excitability is thought to be part of migraine pathophysiology. Reduced magnetic suppression of perceptual accuracy (MSPA) has been found in episodic migraine with aura and in chronic migraine...

    Authors: Veronika Rauschel, Ruth Ruscheweyh, Thomas Eggert and Andreas Straube
    Citation: The Journal of Headache and Pain 2014 15:83
    Content type: Short report Published on:

  22. The pathophysiology of reversible cerebral vasoconstriction syndrome (RCVS) remains elusive. Endothelial dysfunction might play a role, but direct evidence is lacking. This study aimed to explore whether patie...

    Authors: Shih-Pin Chen, Yen-Feng Wang, Po-Hsun Huang, Chin-Wen Chi, Jong-Ling Fuh and Shuu-Jiun Wang
    Citation: The Journal of Headache and Pain 2014 15:82
    Content type: Research article Published on:

  24. In the present school-based study, a convenience sample of 237 adolescents in grade 6-9 and second year in high school (age 12-18 years) was recruited from a city and a smaller town. The aim of the study was t...

    Authors: Bo Larsson and Åsa Fichtel
    Citation: The Journal of Headache and Pain 2014 15:80
    Content type: Research article Published on:

  25. Chronic cluster headache (CCH) often resists to prophylactic pharmaceutical treatments resulting in patients’ life damage. In this rare but pragmatic situation escalation to invasive management is needed but f...

    Authors: Dimos D Mitsikostas, Lars Edvinsson, Rigmor H Jensen, Zaza Katsarava, Christian Lampl, Andrea Negro, Vera Osipova, Koen Paemeleire, Aksel Siva, Dominique Valade and Paolo Martelletti
    Citation: The Journal of Headache and Pain 2014 15:79
    Content type: Consensus article Published on:

  26. Transcranial direct current stimulation (tDCS) of the primary motor cortex has been shown to modulate pain and trigeminal nociceptive processing.

    Authors: Tim Hagenacker, Vera Bude, Steffen Naegel, Dagny Holle, Zaza Katsarava, Hans-Christoph Diener and Mark Obermann
    Citation: The Journal of Headache and Pain 2014 15:78
    Content type: Research article Published on:

  27. In this letter, we present the Austrian proposal for diagnostic criteria of refractory chronic migraine and we discuss the consensensus statement of the European Headache Feaderation. We focus in particular on...

    Authors: Christian Wöber and Peter Wessely
    Citation: The Journal of Headache and Pain 2014 15:77
    Content type: Letter to the Editor Published on:

  28. Most patients with episodic tension-type headache treat headache episodes with over-the-counter medication. Combination analgesics containing caffeine may be more effective and as well tolerated as monotherapy...

    Authors: Hans-Christoph Diener, Morris Gold and Martina Hagen
    Citation: The Journal of Headache and Pain 2014 15:76
    Content type: Research article Published on:

  31. No study has simultaneously investigated the impacts of migraine and anxiety disorders on painful physical symptoms (PPS) among patients with major depressive disorder (MDD). The study aimed to investigate thi...

    Authors: Ching-I Hung, Chia-Yih Liu, Ching-Yen Chen, Ching-Hui Yang and Shuu-Jiun Wang
    Citation: The Journal of Headache and Pain 2014 15:73
    Content type: Research article Published on:

  32. This study aimed to verify and compare central auditory processing (CAP) performance in migraine with and without aura patients and healthy controls.

    Authors: Larissa Mendonça Agessi, Thaís Rodrigues Villa, Karin Ziliotto Dias, Deusvenir de Souza Carvalho and Liliane Desgualdo Pereira
    Citation: The Journal of Headache and Pain 2014 15:72
    Content type: Research article Published on:

  33. Patients with migraine often have impaired somatosensory function and experience headache attacks triggered by exogenous stimulus, such as light, sound or taste. This study aimed to assess the influence of thr...

    Authors: Guangju Yang, Lene Baad-Hansen, Kelun Wang, Qiu-Fei Xie and Peter Svensson
    Citation: The Journal of Headache and Pain 2014 15:71
    Content type: Research article Published on:

  34. To examine the association between headaches and epilepsy.

    Authors: Xiang-qing Wang, Sen-yang Lang, Mian-wang He, Xu Zhang, Fei Zhu, Wei Dai, Xiao-bing Shi, Min Wan, Yun-feng Ma, Ya-nan Chen and Sheng-yuan Yu
    Citation: The Journal of Headache and Pain 2014 15:70
    Content type: Research article Published on:

  35. Limited evidence suggests that dietary interventions may offer a promising approach for migraine. The purpose of this study was to determine the effects of a low-fat plant-based diet intervention on migraine s...

    Authors: Anne E Bunner, Ulka Agarwal, Joseph F Gonzales, Francesca Valente and Neal D Barnard
    Citation: The Journal of Headache and Pain 2014 15:69
    Content type: Research article Published on:

  36. Menstrual migraine (MM) encompasses pure menstrual migraine (PMM) and menstrually-related migraine (MRM). This study was aimed at investigating genetic variants that are potentially related to MM, specifically...

    Authors: Astrid J Rodriguez-Acevedo, Robert A Smith, Bishakha Roy, Heidi Sutherland, Rod A Lea, Alison Frith, E Anne MacGregor and Lyn R Griffiths
    Citation: The Journal of Headache and Pain 2014 15:62
    Content type: Research article Published on:

  37. Headache chronicity has been known to elicit deleterious effects on quality of life (QOL). We evaluated the contribution of headache chronicity to QOL in relation to clinical, psychiatric, and psychosocial var...

    Authors: Sun-Young Kim and Sung-Pa Park
    Citation: The Journal of Headache and Pain 2014 15:68
    Content type: Research article Published on:

  38. This is to our knowledge the first systematic review regarding the efficacy of manual therapy randomized clinical trials (RCT) for primary chronic headaches. A comprehensive English literature search on CINHAL...

    Authors: Aleksander Chaibi and Michael Bjørn Russell
    Citation: The Journal of Headache and Pain 2014 15:67
    Content type: Review article Published on:

  39. The peripheral and central origins of pain in cluster headache (CH) have been a matter of much debate. The development and application of functional imaging techniques have provided more evidence supporting th...

    Authors: Rongfei Wang, Zhao Dong, Xiaoyan Chen, Ruozhuo Liu, Mingjie Zhang, Jinglong Wu and Shengyuan Yu
    Citation: The Journal of Headache and Pain 2014 15:66
    Content type: Research article Published on:

  40. In the majority of cases, trigeminal neuralgia (TN) is a unilateral condition with ultra-short stabbing pain located along one or more branches of the trigeminal nerve. Although prophylactic pharmacological tr...

    Authors: Haifeng Zhang, Yajun Lian, Yunqing Ma, Yuan Chen, Caihong He, Nanchang Xie and Chuanjie Wu
    Citation: The Journal of Headache and Pain 2014 15:65
    Content type: Research article Published on:

  41. Association between sleep disorders and headache is largely known. The aim of the present study was to evaluate sleep quality and quantity in a large cohort of primary headache patients, in order to correlate ...

    Authors: Marina de Tommaso, Marianna Delussi, Eleonora Vecchio, Vittorio Sciruicchio, Sara Invitto and Paolo Livrea
    Citation: The Journal of Headache and Pain 2014 15:64
    Content type: Research article Published on:

  42. Previous studies have shown that 5-HT3-antagonists reduce muscle pain, but there are no studies that have investigated the expression of 5-HT3-receptors in human muscles. Also, tetrodotoxin resistant voltage gate...

    Authors: Nikolaos Christidis, Isabell Kang, Brian E Cairns, Ujendra Kumar, Xudong Dong, Annika Rosén, Sigvard Kopp and Malin Ernberg
    Citation: The Journal of Headache and Pain 2014 15:63
    Content type: Research article Published on:
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