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  1. Most migraineurs develop cutaneous allodynia (CA) during migraine, and the underlying mechanism of CA in migraine is thought to be sensitization of the third-order trigeminovascular neurons in the posterior th...

    Authors: Ting Wang, Ning Chen, Wang Zhan, Jia Liu, Junpeng Zhang, Qi Liu, Hua Huang, Li He, Junran Zhang and Qiyong Gong
    Citation: The Journal of Headache and Pain 2016 17:17
    Content type: Research article Published on:

  2. Reliable information on headache characteristics, including frequency and intensity, headache-associated impairment, and use of analgesic medications, may depend on the assessment method used. This study analy...

    Authors: Anne-Berit Krogh, Bo Larsson, Øyvind Salvesen and Mattias Linde
    Citation: The Journal of Headache and Pain 2016 17:14
    Content type: Research article Published on:

  3. A “Probable headache disorder” is diagnosed when a patient’s headache fulfills all but one criterion of a headache disorder in the 3rd beta edition of the International Classification of Headache Disorder (ICH...

    Authors: Byung-Su Kim, Heui-Soo Moon, Jong-Hee Sohn, Myong-Jin Cha, Tae-Jin Song, Jae-Moon Kim, Jeong Wook Park, Kwang-Yeol Park, Soo-Jin Cho and Soo-Kyoung Kim
    Citation: The Journal of Headache and Pain 2016 17:13
    Content type: Research article Published on:

  6. Oxidative stress is implicated in the pathogenesis of migraine, but no published studies have examined both oxidative stress levels and oxidative DNA damage on the same patient group.

    Authors: Sırma Geyik, Erman Altunısık, Ayse Münife Neyal and Seyithan Taysi
    Citation: The Journal of Headache and Pain 2016 17:10
    Content type: Research article Published on:

  7. Most primary headaches are episodic, and most estimates of the heavy disability burden attributed to headache derive from epidemiological data focused on the episodic subtypes of migraine and tension-type head...

    Authors: Christian Lampl, Hallie Thomas, Lars Jacob Stovner, Cristina Tassorelli, Zaza Katsarava, Jose Miguel Laínez, Michel Lantéri-Minet, Daiva Rastenyte, Elena Ruiz de la Torre, Colette Andrée and Timothy J. Steiner
    Citation: The Journal of Headache and Pain 2016 17:9
    Content type: Research article Published on:

  8. Invasive Occipital Nerve Stimulation (iONS) is a costly technique which appears effective in drug-refractory chronic cluster headache (drCCH) management. Available data on long-term effectiveness and safety of...

    Authors: Delphine Magis, Pascale Gérard and Jean Schoenen
    Citation: The Journal of Headache and Pain 2016 17:8
    Content type: Short report Published on:

  9. The exact pathophysiology of cluster headache is unclear. We examined the influence of interneurons on the trigemino-facial reflex arch and the effect of oxygen, by using the nociception specific blink reflex ...

    Authors: D. Y. P. Haane, A. Plaum, P. J. Koehler and M. P. W. A. Houben
    Citation: The Journal of Headache and Pain 2016 17:7
    Content type: Short report Published on:

  10. The quality of The Journal of Headache and Pain depends on the qualified and regular collaboration of renowned scientists, who devoted their time to constructively review the submitted articles. We are indebted t...

    Authors: Valerio De Angelis
    Citation: The Journal of Headache and Pain 2016 17:6
    Content type: Reviewer acknowledgement Published on:

  11. The diagnosis of primary headache disorders is clinical and based on the diagnostic criteria of the International Headache Society (ICHD-3-beta). However several brain conditions may mimic primary headache dis...

    Authors: D. D. Mitsikostas, M. Ashina, A. Craven, H. C. Diener, P. J. Goadsby, M. D. Ferrari, C. Lampl, K. Paemeleire, J. Pascual, A. Siva, J. Olesen, V. Osipova and P. Martelletti
    Citation: The Journal of Headache and Pain 2016 17:5
    Content type: Consensus article Published on:

  12. Structural white matter abnormalities in pain-modulating, regions are present in migraine. Whether they are associated with pain chronification and with cognitive reserve is unclear.

    Authors: Marian Gomez-Beldarrain, Isabel Oroz, Begoña Garcia Zapirain, Begoña Fernandez Ruanova, Yolanda Garcia Fernandez, Alberto Cabrera, Ane Anton-Ladislao, Urko Aguirre-Larracoechea and Juan Carlos Garcıa-Monco
    Citation: The Journal of Headache and Pain 2016 17:4
    Content type: Research article Published on:

    The Erratum to this article has been published in The Journal of Headache and Pain 2016 17:22

  13. Headache disorders, particularly migraine and tension-type headache (TTH), are among the most prevalent global public-health problems. Medication-overuse headache (MOH) is a common sequela of mismanagement of ...

    Authors: Kedar Manandhar, Ajay Risal, Mattias Linde and Timothy J. Steiner
    Citation: The Journal of Headache and Pain 2016 17:3
    Content type: Research article Published on:

  14. As the most abundant excitatory neurotransmitter in the central nervous system, glutamate has been accepted to play a major role in the pathophysiology of migraine. The previous studies have reported the gluta...

    Authors: Jie Fang, Xingkai An, Shuai Chen, Zhenzhen Yu, Qilin Ma and Hongli Qu
    Citation: The Journal of Headache and Pain 2016 17:2
    Content type: Research article Published on:

  15. The efficacy and safety of OnabotulinumtoxinA (BOTOX®) in adults with chronic migraine (CM) were demonstrated in the PREEMPT program. However, the dosage used in this study was flexible from 155 U to 195 U at ...

    Authors: Andrea Negro, Martina Curto, Luana Lionetto and Paolo Martelletti
    Citation: The Journal of Headache and Pain 2016 17:1
    Content type: Research article Published on:

  16. Pain related to temporomandibular disorders (TMD) is a common problem in modern societies. The aim of the article is to present the concepts of TMD pain clinical management.

    Authors: Mieszko Wieckiewicz, Klaus Boening, Piotr Wiland, Yuh-Yuan Shiau and Anna Paradowska-Stolarz
    Citation: The Journal of Headache and Pain 2015 16:106
    Content type: Review article Published on:

  17. Epileptic seizures and headache attacks are two common neurologic phenomena characterized by paroxysmal alteration of brain functions followed by complete restauration of the baseline condition. Headache and e...

    Authors: Martina Fanella, Alessandra Morano, Jinane Fattouch, Mariarita Albini, Sara Casciato, Mario Manfredi, Anna Teresa Giallonardo and Carlo Di Bonaventura
    Citation: The Journal of Headache and Pain 2015 16:105
    Content type: Case report Published on:

  18. Serotonin (5-HT) mediates pain by peripheral 5-HT3-receptors. Results from a few studies indicate that intramuscular injections of 5-HT3-antagonists may reduce musculoskeletal pain. The aim of this study was to i...

    Authors: Nikolaos Christidis, Shahin Omrani, Lars Fredriksson, Mattias Gjelset, Sofia Louca, Britt Hedenberg-Magnusson and Malin Ernberg
    Citation: The Journal of Headache and Pain 2015 16:104
    Content type: Research article Published on:

  19. The incidence of migraine has been investigated only in a few studies worldwide and it is not known in our country. We, therefore, aimed to estimate the migraine incidence in a previously accomplished populati...

    Authors: Betul Baykan, Mustafa Ertas, Necdet Karlı, Derya Uluduz, Ugur Uygunoglu, Esme Ekizoglu, Elif Kocasoy Orhan, Sabahattin Saip, Mehmet Zarifoglu and Aksel Siva
    Citation: The Journal of Headache and Pain 2015 16:103
    Content type: Research article Published on:

  20. High stress levels and shift work probably trigger migraine in healthcare professionals (HCPs). However, the migraine risk differences between HCPs and the general population is unknown.

    Authors: Wan-Yin Kuo, Chien-Cheng Huang, Shih-Feng Weng, Hung-Jung Lin, Shih-Bin Su, Jhi-Joung Wang, How-Ran Guo and Chien-Chin Hsu
    Citation: The Journal of Headache and Pain 2015 16:102
    Content type: Research article Published on:

  21. The debilitating nature of migraine and challenges associated with treatment-refractory migraine have a profound impact on patients. With the need for alternatives to pharmacologic agents, vagus nerve stimulat...

    Authors: Thomas M. Kinfe, Bogdan Pintea, Sajjad Muhammad, Sebastian Zaremba, Sandra Roeske, Bruce J. Simon and Hartmut Vatter
    Citation: The Journal of Headache and Pain 2015 16:101
    Content type: Research article Published on:

  22. Migraine, tension-type headache (TTH) and medication-overuse headache (MOH) are disabling lifelong illnesses. The Eurolight project, a partnership activity within the Global Campaign against Headache, assessed...

    Authors: M. Allena, T. J. Steiner, G. Sances, B. Carugno, F. Balsamo, G. Nappi, C. Andrée and C Tassorelli
    Citation: The Journal of Headache and Pain 2015 16:100
    Content type: Research article Published on:

  23. The trigeminal ganglion (TG) plays a central role in cranial pain. Administration of complete Freund’s adjuvant (CFA) into the temporomandibular joint (TMJ) elicits activation of TG. Kynurenic acid (KYNA) is a...

    Authors: A. Csáti, L. Edvinsson, L. Vécsei, J. Toldi, F. Fülöp, J. Tajti and K. Warfvinge
    Citation: The Journal of Headache and Pain 2015 16:99
    Content type: Research article Published on:

  24. Alexithymia is a personality construct characterized by difficulties in verbal emotional expression and a limited ability to use one’s imagination. Evidence of alexithymic characteristics was found in adults s...

    Authors: M. Gatta, C. Spitaleri, U. Balottin, A. Spoto, L. Balottin, S. Mangano and P.A. Battistella
    Citation: The Journal of Headache and Pain 2015 16:98
    Content type: Research article Published on:

  26. Headache disorders cause substantial productivity losses through absenteeism and impaired effectiveness at work (presenteeism). We had previously found these losses to be high in a mostly male, heavy-manufactu...

    Authors: H. Macit Selekler, Gürsel Gökmen, T. Müge Alvur and Timothy J. Steiner
    Citation: The Journal of Headache and Pain 2015 16:96
    Content type: Research article Published on:

  27. Headache disorders are among the most prevalent and burdensome global public-health problems. Within countries, health policy depends upon knowledge of health within the local populations, but the South-East A...

    Authors: Kedar Manandhar, Ajay Risal, Timothy J Steiner, Are Holen and Mattias Linde
    Citation: The Journal of Headache and Pain 2015 16:95
    Content type: Research article Published on:

  28. Headache disorders are common worldwide, causing pain and disability. India appears to have a very high prevalence of migraine, and of other headache disorders in line with global averages. Our objective was t...

    Authors: Girish N. Rao, Girish B. Kulkarni, Gopalkrishna Gururaj, Lars J. Stovner and Timothy J. Steiner
    Citation: The Journal of Headache and Pain 2015 16:94
    Content type: Research article Published on:

  29. Many studies have identified various vestibular symptoms and laboratory abnormalities in migraineurs. Although the vestibular tests may be abnormal, the changes may exist without vestibular symptoms. To date, ...

    Authors: Chul-Ho Kim, Min-Uk Jang, Hui-Chul Choi and Jong-Hee Sohn
    Citation: The Journal of Headache and Pain 2015 16:93
    Content type: Research article Published on:

  30. Patients suffering from migraine with aura can have either pure visual auras or complex auras with sensory disturbances and dysphasia, or both. Few studies have searched for possible pathophysiological differe...

    Authors: Gianluca Coppola, Martina Bracaglia, Davide Di Lenola, Cherubino Di Lorenzo, Mariano Serrao, Vincenzo Parisi, Antonio Di Renzo, Francesco Martelli, Antonello Fadda, Jean Schoenen and Francesco Pierelli
    Citation: The Journal of Headache and Pain 2015 16:92
    Content type: Research article Published on:

  31. Migraine is a paroxysmal, disabling primary headache that affects 16 % of the adult population. In spite of decades of intense research, the origin and the pathophysiology mechanisms involved are still not ful...

    Authors: Cornelia Lundblad, Kristian A. Haanes, Gustaf Grände and Lars Edvinsson
    Citation: The Journal of Headache and Pain 2015 16:91
    Content type: Research article Published on:

  32. Receptor activity modifying protein 1(RAMP1) is a key receptor subunit of calcitonin gene related peptide (CGRP) playing a critical role in migraine. But variations in RAMP1 gene have not been found to link wi...

    Authors: Dongjun Wan, Lei Hou, Xiaofei Zhang, Xun Han, Min Chen, Wenjing Tang, Ruozhuo Liu, Zhao Dong and Shengyuan Yu
    Citation: The Journal of Headache and Pain 2015 16:90
    Content type: Research article Published on:

  33. The impact of headache on dementia is largely unknown. This study examined the association between headache and dementia using data from a large population-based study.

    Authors: Ane Karoline Stræte Røttereng, Ole Bosnes, Eystein Stordal, John-Anker Zwart, Mattias Linde, Lars Jacob Stovner and Knut Hagen
    Citation: The Journal of Headache and Pain 2015 16:89
    Content type: Research article Published on:

  34. Sleep disorders and primary headaches are both more prevalent among nursing staff than in the general population. However, there have been no reports about the comorbidity of poor sleep and primary headaches a...

    Authors: Yan Wang, Jingdan Xie, Fei Yang, Shiwen Wu, Hebo Wang, Xiaolan Zhang, Hua Liu, Xin Deng, Wei Xie and Shengyuan Yu
    Citation: The Journal of Headache and Pain 2015 16:88
    Content type: Research article Published on:

  35. The physiology and pharmacology of activation or perception of activation of pain-coding trigeminovascular afferents in humans is fundamental to understanding the biology of headache and developing new treatme...

    Authors: JCA Marin, AR Gantenbein, K. Paemeleire, H. Kaube and PJ Goadsby
    Citation: The Journal of Headache and Pain 2015 16:87
    Content type: Research article Published on:

  36. Both hypertension (HTN) and headache disorders are highly prevalent worldwide. Our purpose, in a nationwide study of the Chinese general population, was to evaluate any association between primary headache dis...

    Authors: Mianwang He, Shengyuan Yu, Ruozhuo Liu, Xiaosu Yang, Gang Zhao, Xiangyang Qiao, Jiachun Feng, Yannan Fang, Xiutang Cao and Timothy J. Steiner
    Citation: The Journal of Headache and Pain 2015 16:86
    Content type: Research article Published on:

  37. There is abundance of epidemiological studies of headache in developed and western countries; however, data in developing countries and in Egypt are still lacking. This study aims to detect the prevalence of p...

    Authors: Naglaa A. El-Sherbiny, Mohamed Masoud, Nevin M. Shalaby and Hatem S. Shehata
    Citation: The Journal of Headache and Pain 2015 16:85
    Content type: Research article Published on:

  39. Authors: Davide Di Lenola, Gianluca Coppola, Mariano Serrao, Cherubino Di Lorenzo and Francesco Pierelli
    Citation: The Journal of Headache and Pain 2015 16(Suppl 1):A160
    Content type: Oral presentation Published on:

    This article is part of a Supplement: Volume 16 Supplement 1

    The Erratum to this article has been published in The Journal of Headache and Pain 2017 18:11

  40. Authors: Gianluca Coppola, Francesca Napoli, Davide Di Lenola, Martina Bracaglia, Mariano Serrao, Cherubino Di Lorenzo and Francesco Pierelli
    Citation: The Journal of Headache and Pain 2015 16(Suppl 1):A158
    Content type: Oral presentation Published on:

    This article is part of a Supplement: Volume 16 Supplement 1

    The Erratum to this article has been published in The Journal of Headache and Pain 2017 18:11

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