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Table 2 Treatment uptake, use of resources and lost productivity according to treatment management plan (Russia)

From: Structured headache services as the solution to the ill-health burden of headache. 2. Modelling effectiveness and cost-effectiveness of implementation in Europe: methodology

 

Headache type

Current care (%)

Target care (%)

Notes

Uptake (including coverage and adherence)

Migraine

64.7

82.0

Current care:

63.5% migraine non-specific; 0.5% migraine specific; 0.7% migraine prophylaxis

Target care: We assumed that structured services with consumer education and provider training enhances coverage and adherence so that overall uptake is increased by 50%; medicines uptake = [{100% - 64.7%}/2] + 64.7%) = 82.0%

TTH

55.6

77.8

55.6% (acute medications) TTH; 0% TTH prophylaxis (see treatment plan below)

Target care: We assumed as above; medicines uptake = [{100% - 55.6%}/2] + 55.6%) = 77.8%

MOH

0

50.0

Current care: 0% treated

Target care: We assumed that structured services with consumer education and provider training enhances treatment coverage and adherence so that proportion withdrawn from medicines overuse is increased by 50% of current deficit: withdrawal = [{100–0%}/2] + 0%) = 50%

TREATMENT PLAN

 A. Acute management (non-specific drugs)

  Simple analgesics (eg, ASA 1 g)

Migraine

63.5

41.0

Current care: from Eurolight data [20]

Target care: With provider training, treatment with simple analgesics alone is offered to 50% (expert assumption), with uptake = 41.0% (50% of 82.0%)

TTH

55.6

75.5

Current care: from Eurolight data [20]

Target care: With provider training, treatment with simple analgesics alone is offered to 97% (expert assumption), with uptake = 75.5% (97% of 77.8%)

MOH

0

0

Not applicable to MOH care

 B. Acute management (specific drugs)

  Sumatriptan 50 mg

Migraine

0.5

0

Current care: from Eurolight data [20]

Target care: With provider training, treatment with specific drugs alone is offered to 0% (expert assumption)

TTH

0

0

Not applicable to TTH care

MOH

0

0

Not applicable to MOH care

 C. Acute stepped-care management

  ASA 1 g + sumatriptan 50 mg

Migraine

0

16.4

Current care: not included in current care

Target care: With provider training, acute stepped-care management is offered to 20% (expert assumption), with uptake = 16.4% (20% of 82.0%)

TTH

0

0

Not applicable to TTH care

MOH

0

0

Not applicable to MOH care

 D. Prophylaxis + acute management

  Amitriptyline 100 mg/day + ASA 1 g + sumatriptan 50 mg

Migraine

0.7

24.6

Current care: from Eurolight data [20]

Target care: With provider training, prophylaxis + acute stepped-care management is offered to 30% (expert assumption), with uptake = 24.6% (30% of 82.0%)

TTH

0

2.3

Current care: not included in current care

Target care: With provider training, prophylaxis + acute care management is offered to 3% (expert assumption), with uptake = 2.3% (3% of 77.8%)

MOH

0

0

Not applicable to MOH care

Consultations and investigations

 Doctor visits (year 1)

Migraine

25.1

50.0

Current care: 25.1% with migraine had seen a doctor (Eurolight data [20]), of whom 19.3% had seen a GP and 5.8% a specialist. We assumed 2 visits in either case.

Target care: With consumer education, 50% see a doctor (expert assumption based on estimated need for professional care).

Note that in the model those who see a specialist would see a GP first.

TTH

9.4

2.25

Current care: 9.4% with TTH had seen a doctor (Eurolight data [20]), of whom 6.9% had seen a GP and 2.5% a specialist. We assumed 2 visits in either case.

Target care: With consumer education, 3% (Stovner 2007 [21]) ×  75% = 2.25% see a specialist and none see a GP (expert assumption based on estimated need for professional care).

Note that those who see a specialist would see a GP first.

MOH

51.2

100

Current care: 51.2% with MOH had seen a doctor (Eurolight data [20]), of whom 21.6% had seen a GP and 29.6% a specialist. We assumed 2 visits in either case.

Target care: With consumer education, 100% see a doctor (expert assumption based on estimated need for professional care).

Note that those who see a specialist would see a GP first.

 GP visits

Migraine

19.3

45.0

Current care: 19.3% had seen a GP (Eurolight data [20])

Target care: With consumer education, 45.0% (90% of 50%) see a GP (we assumed 2 visits in a year)

TTH

6.9

0

Current care: 6.9% had seen a GP (2 times in a year) (Eurolight data [20])

Target care: Chronic TTH is difficult to treat, so we assumed that all should go to levels 2 or 3 (ie, “specialists”).

Note that those who see a specialist would see a GP first.

MOH

21.6

100

Current care: 21.6% had seen a GP (2 times in a year) (Eurolight data [20])

Target care: With consumer education, 100% see a GP (we assumed 2 visits in a year)

 Specialist visits

Migraine

5.8

5.0

Current care: 5.8% had seen a specialist (2 times in a year)

Target care: With consumer education and provider training, 5.0% (10% of 50%) see a specialist (we assumed 2 visits in a year)

TTH

2.5

2.25

Current care: 2.5% had seen a specialist (2 times in a year)

Target care: With consumer education and provider training, 2.25% see a specialist (we assumed 2 visits in a year)

MOH

29.6

100

Current care: 29.6% saw a GP (2 times in a year)

Target care: With consumer education and provider training, 100% see a specialist (we assumed 2 visits in a year)

 Investigations (MRI) (year one)

Migraine

8.5

1.0

Current care: All those seeing a specialist had MRI (one in a year)

Target care: With provider training, we assumed 1% have MRI (one in a year)

TTH

1.0

0.5

Current care: 1% had an MRI

Target care: We assumed 0.5% have MRI examination (one in a year) – half the current estimate

MOH

0

0

Current care: Nobody had an MRI

Target care: Nobody has an MRI

 Doctor visits (years 2–5)

Migraine

24.6

50.0

Current care: 24.6% with migraine had seen a doctor (Eurolight data [20]), of whom all saw a GP only after year 1. We assumed 2 visits per year.

Target care: With consumer education, 50% see a doctor (expert assumption based on estimated need for professional care)

TTH

9.4

2.25

Current care: 9.4% with TTH had seen a doctor (Eurolight data [20]), of whom all saw a GP only after year 1. We assumed 2 visits per year.

Target care: With consumer education, 3% (Stovner 2007 [21]) ×  75% = 2.25% see a doctor (expert assumption based on estimated need for professional care).

Note that those who see a specialist would see a GP first.

MOH

51.2

100

Current care: 51.2% with MOH had seen a doctor (Eurolight data [20]), of whom all saw a GP only after year 1. We assumed 2 visits per year.

Target care: With consumer education, 100% see a doctor

 GP visits

Migraine

24.6

50.0

Current care: 24.6% saw a GP. We assumed 2 visits each year.

Target care: With consumer education, 50% see a GP. We assumed 2 visits each year.

TTH

9.4

0

Current care: 9.4% saw a GP. We assumed 2 visits each year.

Target care: Chronic TTH is difficult to treat, so we assumed that all should go to levels 2 or 3 (ie, “specialists”).

Note that those who see a specialist would see a GP first.

MOH

51.2

100

Current care: 51.2% saw a GP. We assumed 2 visits each year.

Target care: With consumer education, 100% see a GP. We assumed 2 visits each year.

 Specialist visits

Migraine

0

0

Current care: No visits after year 1

Target care: No visits after year 1

TTH

0

2.25

Current care: No visits after year 1

Target care: With consumer education and provider training, 2.25% see a specialist (we assumed 2 visits in a year).

MOH

0

0

Current care: No visits after year 1

Target care: No visits after year 1

 Investigation (MRI) (years 2–5)

Migraine

0

0

Current care: nobody had an MRI after year 1

Target care: nobody had an MRI after year 1

TTH

0

0

Current care: nobody had an MRI after year 1

Target care: nobody had an MRI after year 1

MOH

0

0

Current care: nobody had an MRI after year 1

Target care: nobody had an MRI after year 1

 Lost productivity

We assumed that lost work productivity is correlated with disease-related disability, and reduced disability would bring reduced lost productivity. In our baseline scenario, all lost productivity was explained by disease-related disability.

 Days lost from work in 12 months

Migraine

7.6

3.9

Current care: based on Eurolight data [16]

Target care: we assumed 49% decrease in lost productivity (equal to the gain in HLYs reported for migraine (see Table 4)): 7.6-(7.6*0.49) = 3.9 days.

TTH

3.2

1.0

Current care: based on Eurolight data [16]

Target care: we assumed 68% decrease in lost productivity (equal to the gain in HLYs reported for TTH (see Table 4)): 3.2-(3.2*0.68) = 1.0 days.

MOH

22.8

11.6 (if revert to migraine);

7.3 (if revert to TTH)

Current care: based on Eurolight data [16]

Target care: for individuals reverting to migraine, we assumed 49% decrease in lost productivity (equal to the gain in HLYs reported for migraine (see Table 4)): 22.8 - (22.8*0.49) = 11.6 days

for individuals reverting to TTH, we assumed 76% decrease in lost productivity (equal to the gain in HLYs reported for TTH (see Table 4)): 22.8-(22.8*0.68) = 7.3 days.