Structured headache services as the solution to the ill-health burden of headache. 2. Modelling effectiveness and cost-effectiveness of implementation in Europe: methodology

Table 12 Unit costs

	Luxembourg Cost per year per capita (euro) 2020	Russia Cost per year per capita (euro) 2020	Spain Cost per year per capita (euro) 2020	References
MEDICINES				[5, 17, 19]. Costs actualised to 2020 values using appropriate consumer price index [27]
A. Acute management (non-specific drugs)
ASA 1 g	0.10	0.07	0.07
Paracetamol 1 g	0.297	0.23	0.23
With consumer education	0.33	0.21	0.08
B. Acute management (specific drugs)
Sumatriptan 50 mg	6.06	13.85	4.86
With consumer education and provider training	6.07	14.09	4.87
C. Acute stepped-care management
ASA 1 g + sumatriptan 50 mg	6.16	17.35	4.94
With consumer education and provider training	7.82	17.59	6.07
D. Prophylaxis + acute management
Amitriptyline 100 mg + ASA 1 g + sumatriptan 50 mg	0.83	1.60	0.29
With consumer education and provider training	1.02	1.83	0.35
VISITS
One GP visit	38.76	22.86	41.13	[25]
One specialist visit	48.92	40.85	42.74	[25]
EXAMINATION
One MRI	49.91	49.91	49.91	[7]
PRODUCTIVITY
Daily wages	205.01	23.87	81.21	[27]

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