Table 1 Affinity constants indicated as IC₅₀ in nM (and the corresponding pIC₅₀) for the compounds used in the present study

CGS21680³³

22 nM (7.6)

3100 nM (5.5)

141

Caffeine²⁸

8100 nM (5.1)

20,000 nM (4.7)

2.5

JNJ-39928122^a

7.9 nM ^λ (8.1)

55.1 nM ^λ (7.3)

7

JNJ-40529749^a

4.9 nM (8.3)

89.1 nM (7.1)

18

JNJ-41942914^a

8.3 nM (8.1)

1093 nM (6.0)

132

JNJ-40064440^a

8.2 nM (8.1)

1240 nM (5.9)

151

JNJ-41501798^a

11.5 nM (7.9)

7997 nM (5.1)

695