Table 4 Clinical characteristics associated with migraine’s phenotype

Demographics

Age, y

47.0 (41.0, 51.5)

28.0 (23.8, 38.2)

0.013^†

Female

7 (100.0%)

28 (87.5%)

> 0.999^*

Comorbidities

Anxiety

5 (71.4%)

20 (62.5%)

> 0.999^*

Depression

1 (14.3%)

5 (15.6%)

> 0.999^*

Migraine characteristics

Duration of migraine disease, y

27.0 (22.0, 34.5)

15.5 (8.0, 25.5)

0.040^‡

Aura

1 (14.3%)

19 (59.4%)

0.044^*

Headache frequency (MHD), d/mo

18.0 (14.0, 23.0)

9.5 (6.0, 16.0)

0.010^†

Migraine frequency (MMD), d/mo

8.0 (6.0, 16.0)

6.0 (3.0, 10.0)

0.108^‡

Acute medication frequency, d/mo

10.0 (8.5, 16.0)

8.0 (6.0, 12.2)

0.136^‡

Migraine-related clinical burden

Disability (MIDAS), score

31.0 (19.0, 69.5)

22.5 (10.0, 56.5)

0.410^‡

Headache-related impact (HIT-6), score

66.0 (66.0, 67.0)

64.0 (61.0, 68.0)

0.335^†