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Table 3 Clinical characteristics associated with CGRP dependent and non-CGRP dependent headache attacks

From: Dynamic fluctuations of salivary CGRP levels during migraine attacks: association with clinical variables and phenotypic characterization

Variables

Non-CGRP dependent

(n = 18)

CGRP dependent

(n = 62)

Missing

P value

Attack characteristics

    

Aura

5 (35.7%)

10 (20.4%)

17

0.291†

Pain intensity, (0–10)

6.0 (5.0, 7.0)

6.0 (5.0, 8.0)

22

0.584‡

Treated attack at 2 h

10 (100.0%)

24 (50.0%)

22

0.003†

Accompanying symptoms

    

Unilateral pain

6 (50.0%)

14 (30.4%)

22

0.307†

Throbbing pain

6 (50.0%)

9 (19.1%)

21

0.058†

Nausea

5 (41.7%)

27 (57.4%)

21

0.353†

Vomiting

0 (0.0%)

4 (8.5%)

21

0.572†

Photophobia

12 (100.0%)

36 (76.6%)

21

0.098†

Phonophobia

10 (83.3%)

31 (66.0%)

21

0.311†

Osmophobia

2 (16.7%)

10 (21.3%)

21

> 0.999†

Allodynia

3 (25.0%)

28 (59.6%)

21

0.046†

Dizziness

4 (33.3%)

17 (36.2%)

21

0.734†

Swelling

5 (41.7%)

3 (6.4%)

21

0.006†

Cervical pain

7 (58.3%)

10 (21.3%)

21

0.027†

Ocular pain

7 (58.3%)

5 (10.6%)

21

0.001†

  1. Continuous data is represented in median (IQR) and categorical data in % (n). IQR: interquartile range
  2. Bold font indicates statistically significant variables
  3. †Statistical significance assessed with Fisher’s exact test
  4. ‡Statistical significance assessed with unpaired t-test