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Fig. 7 | The Journal of Headache and Pain

Fig. 7

From: Unveiling the therapeutic potential of Dl-3-n-butylphthalide in NTG-induced migraine mouse: activating the Nrf2 pathway to alleviate oxidative stress and neuroinflammation

Fig. 7

Effect of NBP on Nrf2 protein expression levels in nuclear and total cells of SP5C and HO-1, NQO-1 protein expression levels. A, B, C, D Nuclear and total cellular Nrf2 protein expression was decreased in the NTG + Oil group compared to the Control + Oil group, and increased in the NTG + NBP group compared to the NTG + Oil group. E, F, G HO-1 and NQO-1 protein expression was decreased in the NTG + Oil group compared to the Control + Oil group and increased in the NTG + NBP group compared to the NTG + Oil group. (n = 3–5 in each group; **p <0.01, ***p < 0.001 and ****p < 0.0001 compared with the Control + Oil group; #p < 0.05, ##p < 0.01 and ####p < 0.0001 compared with the NTG + Oil group)

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The Journal of Headache and Pain

ISSN: 1129-2377

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