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Fig. 5 | The Journal of Headache and Pain

Fig. 5

From: Lipopolysaccharide, VE-cadherin, HMGB1, and HIF-1α levels are elevated in the systemic circulation in chronic migraine patients with medication overuse headache: evidence of leaky gut and inflammation

Fig. 5

Data are shown as whisker-box plots (whisker: full range; line: median). CM + MOH patients with IBS had significantly higher serum VE-cadherin levels compared to CM + MOH patients without IBS (p = 0.045). Data analysis was performed with Mann-Whitney’s U test. * p < 0.05

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