Measures | Age groups of participants | Time periods identified | Temporal trend | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
APCb | AAPCd | ||||||||||
% | 95%CIc | P value | % | 95% CI | P value | ||||||
ASIR | Overall | Period1 | 1990–1996 | -0.02 | (-0.05, -0.00) | 0.05 |  |  |  | ||
 |  | Period2 | 1996–2000 | -0.35 | (-0.42, -0.29) |  < 0.001 |  |  |  | ||
 |  | Period3 | 2000–2005 | 1.03 | (0.99, 1.07) |  < 0.001 | 0.18 | (0.17, 0.20) |  < 0.001 | ||
 |  | Period4 | 2005–2017 | -0.03 | (-0.04, -0.02) |  < 0.001 |  |  |  | ||
 |  | Period5 | 2017–2019 | 1.06 | (0.93, 1.20) |  < 0.001 |  |  |  | ||
CIR |  | Period1 | 1990–1995 | -0.13 | (-0.17, -0.08) |  < 0.001 |  |  |  | ||
 |  | Period2 | 1995–2000 | -0.47 | (-0.52, -0.41) |  < 0.001 |  |  |  | ||
 | Overall | Period3 | 2000–2005 | 1.04 | (0.98, 1.09) |  < 0.001 |  |  |  | ||
 |  | Period4 | 2005–2012 | -0.27 | (-0.30, -0.24) |  < 0.001 | 0.06 | (0.04, 0.08) |  < 0.001 | ||
 |  | Period5 | 2012–2017 | -0.01 | (-0.07, 0.05) | 0.71 |  |  |  | ||
 |  | Period6 | 2017–2019 | 0.79 | (0.62, 0.97) |  < 0.001 |  |  |  | ||
 |  | Period1 | 1990–1996 | -0.04 | (-0.11, 0.03) | 0.25 |  |  |  | ||
 |  | Period2 | 1996–2000 | -0.77 | (-0.97, -0.56) |  < 0.001 |  |  |  | ||
 | 15–19 years | Period3 | 2000–2004 | 1.25 | (1.05, 1.46) |  < 0.001 | 0.24 | (0.19, 0.28) |  < 0.001 | ||
 |  | Period4 | 2004–2017 | -0.05 | (-0.08, -0.03) |  < 0.001 |  |  |  | ||
 |  | Period5 | 2017–2019 | 2.98 | (2.56, 3.40) |  < 0.001 |  |  |  | ||
 |  | Period1 | 1990–1996 | -0.05 | (-0.08, -0.02) | 0.01 |  |  |  | ||
 |  | Period2 | 1996–2000 | -0.73 | (-0.82, -0.65) |  < 0.001 |  |  |  | ||
 | 20–24 years | Period3 | 2000–2005 | 0.88 | (0.83, 0.94) |  < 0.001 | 0.13 | (0.12, 0.15) |  < 0.001 | ||
 |  | Period4 | 2005–2017 | 0.02 | (0.004, 0.03) | 0.01 |  |  |  | ||
 |  | Period5 | 2017–2019 | 1.25 | (1.08, 1.44) |  < 0.001 |  |  |  | ||
 |  | Period1 | 1990–1996 | -0.02 | (-0.03, -0.004) | 0.02 |  |  |  | ||
 |  | Period2 | 1996–2000 | -0.19 | (-0.23, -0.15) |  < 0.001 |  |  |  | ||
 | 25–29 years | Period3 | 2000–2005 | 0.92 | (0.89, 0.94) |  < 0.001 |  |  |  | ||
 |  | Period4 | 2005–2009 | -0.26 | (-0.30, -0.22) |  < 0.001 | 0.15 | (0.14, 0.16) |  < 0.001 | ||
 |  | Period5 | 2009–2017 | -0.02 | (-0.03, -0.01) | 0.001 |  |  |  | ||
 |  | Period6 | 2017–2019 | 0.97 | (0.89, 1.05) |  < 0.001 |  |  |  | ||
 |  | Period1 | 1900–1996 | -0.02 | (-0.04, -0.01) | 0.01 |  |  |  | ||
 |  | Period2 | 1996–2000 | -0.25 | (-0.29, -0.20) |  < 0.001 |  |  |  | ||
 | 30–34 years | Period3 | 2000–2005 | 1.08 | (1.05, 1.11) |  < 0.001 |  |  |  | ||
 |  | Period4 | 2005–2009 | -0.37 | (-0.42, -0.33) |  < 0.001 | 0.14 | (0.13, 0.15) |  < 0.001 | ||
 |  | Period5 | 2009–2017 | -0.02 | (-0.03, -0.01) | 0.01 |  |  |  | ||
 |  | Period6 | 2017–2019 | 0.77 | (0.67, 0.87) |  < 0.001 |  |  |  | ||
 |  | Period1 | 1990–1996 | 0.001 | (-0.01, 0.02) | 0.94 |  |  |  | ||
 |  | Period2 | 1996–2000 | -0.27 | (-0.31, -0.23) |  < 0.001 |  |  |  | ||
 | 35–39 years | Period3 | 2000–2005 | 1.04 | (1.01, 1.06) |  < 0.001 | 0.18 | (0.17, 0.19) |  < 0.001 | ||
 |  | Period4 | 2005–2009 | 0.29 | (0.25, 0.33) |  < 0.001 |  |  |  | ||
 |  | Period5 | 2009–2019 | 0.01 | (-0.001, 0.01) | 0.1 |  |  |  | ||
 |  | Period1 | 1990–1998 | 0.01 | (-0.02, 0.03) | 0.58 |  |  |  | ||
 |  | Period2 | 1998–2001 | 0.26 | (0.07, 0.45) | 0.01 |  |  |  | ||
 | 40–44 years | Period3 | 2001–2004 | 1.43 | (1.24, 1.62) |  < 0.001 | 0.25 | (0.22, 0.28) |  < 0.001 | ||
 |  | Period4 | 2004–2008 | 0.44 | (0.35, 0.54) |  < 0.001 |  |  |  | ||
 |  | Period5 | 2008–2019 | 0.03 | (0.02, 0.04) |  < 0.001 |  |  |  | ||
 |  | Period1 | 1990–2001 | -0.01 | (-0.04, 0.02) | 0.34 |  |  |  | ||
 | 45–49 years | Period2 | 2001–2004 | 2.2 | (1.74, 2.66) |  < 0.001 | 0.21 | (0.16, 0.25) |  < 0.001 | ||
 |  | Period3 | 2004–2019 | -0.03 | (-0.05, -0.01) | 0.01 |  |  |  |