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Fig. 1 | The Journal of Headache and Pain

Fig. 1

From: Progesterone distribution in the trigeminal system and its role to modulate sensory neurotransmission: influence of sex

Fig. 1

Progesterone immunoreactivity in TG. A-C Progesterone was expressed in the cell surface of TG neurons (thick arrows) and had a weak expression in Aδ-fibers (arrowheads). In addition, progesterone immunoreactivity was seen in the cytoplasm of a few small to medium sized neurons (thin arrows, A and B). Negative cells are marked with asterisk in Fig. 1B. B and C showing higher magnification of image A. Blue colors represent nucleus staining with DAPI. D The bar graphs show progesterone immunoreactive cells in females (60.6% ± 7) and males (49% ± 4) of the total number of neurons. This was significantly higher in female rats. Data are presented as the mean ± SEM, n = 6, and *P < 0.05

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