Increased glymphatic system activity in migraine chronification by diffusion tensor image analysis along the perivascular space

Table 3 Correlations between DTI-ALPS index and clinical characteristics of migraine

Variables	Left DTI-ALPS index		Right DTI-ALPS index
Variables	r	p	r	p
BMI (kg/m²)	-0.083	0.551	-0.014	0.922
Disease duration (years)	0.189	0.209	0.181	0.229
Age of onset (years)	-0.190	0.206	-0.181	0.229
Headache intensity (VAS)	0.371	0.011	0.307	0.038
Attacks frequency (days/month)	0.081	0.592	0.137	0.363
MIDAS score^a	0.165	0.272	0.125	0.408
HIT-6 score^a	-0.094	0.534	0.009	0.955
PHQ-9 score^a	0.243	0.104	0.107	0.479
GAD-7 score^a	0.192	0.201	0.192	0.201
PSQI score^a	0.013	0.934	0.094	0.533

Statistical significance: p < 0.0025 (Bonferroni correction)
DTI-ALPS Diffusion tensor image analysis along the perivascular space, EM Episodic migraine, CM Chronic migraine, BMI Body mass index, MIDAS Migraine Disability Assessment, HIT-6 Headache Impact Test-6, PHQ-9 Patient Health Questionnaire-9, GAD-7 Generalized Anxiety Disorder-7; PSQI, Pittsburgh Sleep Quality Index
^aAvailable to 48 patients with migraine

ISSN: 1129-2377