Impact of headache frequency and preventive medication failure on quality of life, functioning, and costs among individuals with migraine across several European countries: need for effective preventive treatment

Table 2 Health-related quality of life: work and household activities days missed due to migraine

Group	Work Days Missed Due to Migraine^a		Household Activity Days Missed Due to Migraine^a
	Mean (SE)	P value^b	Mean (SE)	P value^b
Preventive naive (n = 500)	4.3 (0.6)	< 0.001	10.6 (0.8)	< 0.001
0–1 preventive failures (n = 308)	7.0 (1.0)	0.281	12.0 (1.0)	0.043
≥ 2 preventive failures (n = 298)	7.8 (1.1)	––	14.3 (1.2)	––

Results were adjusted for age, sex, country, insurance type, body mass index category, smoking history, alcohol intake, exercise, CCI, PHQ-9, and GAD-7. Higher numbers of days missed are reflective of poorer outcomes
CCI Charlson Comorbidity Index, GAD-7 Generalized Anxiety Disorder-7, PHQ-9 Patient Health Questionnaire-9, SE Standard error
^aDays in the past 6 months
^bP value vs ≥ 2 preventive treatment failures group

ISSN: 1129-2377