Fig. 4From: Impact of headache frequency and preventive medication failure on quality of life, functioning, and costs among individuals with migraine across several European countries: need for effective preventive treatmentHealth-related economic burden: WPAI subscales. Results were adjusted for age, sex, country, insurance type, body mass index category, smoking history, alcohol intake, exercise, CCI, PHQ-9, and GAD-7. *P < 0.05, †P < 0.01 vs ≥ 2 preventive treatment failures group. CCI, Charlson Comorbidity Index; GAD-7, Generalized Anxiety Disorder-7; PHQ-9; Patient Health Questionnaire-9; WPAI, Work Productivity and Activity ImpairmentBack to article page