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Table 3 New users: Hazard ratio of treatment discontinuation

From: Persistence to anti-CGRP monoclonal antibodies and onabotulinumtoxinA among patients with migraine: a retrospective cohort study

 

Cox Model Hazard Ratio a

(95% confidence interval) b

 

15-day gap

n = 30,507

30-day gap

n = 30,507

60-day gap

n = 30,507

Erenumab

1.48 (1.20, 1.90)

1.25 (0.99, 1.66)

1.08 (0.80, 1.54)

Fremanezumab

1.68 (1.36, 2.16)

1.45 (1.13, 1.95)

1.26 (0.92, 1.80)

Galcanezumab

1.55 (1.25, 1.97)

1.27 (0.99, 1.68)

1.11 (0.82, 1.59)

OnabotulinumtoxinA

1.17 (0.95, 1.49)

1.07 (0.84, 1.43)

1.09 (0.82, 1.54)

Eptinezumab

Reference

Reference

Reference

  1. aAdjusted for all covariates (including age, sex, insurance type, migraine type, comorbidities, prescriber, history of non–anti-CGRP oral preventives, history of acute medication use, and history of inpatient/outpatient/ER visits)
  2. bBoot-strapped confidence interval