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Table 2 Shows both groups’ migraine days/month, intensity, HIT-6, and MIDAS at the baseline and after three months of each diet; results for chronic and high-frequency episodic migraineurs are also presented. There was a significant reduction in all variables studied. A paired t-test or a Wilcoxon test was used to compare; significance was determined with a p-value of 0.05

From: 2:1 ketogenic diet and low-glycemic-index diet for the treatment of chronic and episodic migraine: a single-center real-life retrospective study

 

Baseline (mean ± SD)

3 months (mean ± SD)

p-value

LGID ( n  = 39)

 MIDAS

75.821 ± 80.493

32.051 ± 52.307

< 0.001

 HIT-6

63.905 ± 8.854

52.714 ± 11.538

< 0.001

 Migraine days/month

18.744 ± 8.478

9.154 ± 10.676

< 0.001

 Migraine Intensity (NRS)

8.051 ± 1.075

4.846 ± 2.852

< 0.001

LGID chronic ( n  = 23)

 MIDAS

84.174 ± 89.294

44.652 ± 64.558

< 0.001

 HIT-6

64.783 ± 6.466

55.870 ± 12.871

0.001

 Migraine days/month

24.435 ± 6.302

12.522 ± 12.616

< 0.001

 Migraine Intensity (NRS)

7.739 ± 0.964

5.000 ± 2.908

< 0.001

LGID episodic ( n  = 16)

 MIDAS

63.813 ± 66.774

13.938 ± 15.004

< 0.001

 HIT-6

63.813 ± 9.389

52.625 ± 12.842

< 0.001

 Migraine days/month

10.563 ± 1.672

4.313 ± 3.591

< 0.001

 Migraine Intensity (NRS)

8.500 ± 1.095

4.625 ± 2.849

< 0.001

2:1 KD ( n  = 21)

 MIDAS

69.762 ± 58.665

31.524 ± 52.018

< 0.001

 HIT-6

61.231 ± 11.840

53.250 ± 16.341

< 0.001

 Migraine days/month

15.857 ± 8.374

6.476 ± 5.776

< 0.001

 Migraine Intensity (NRS)

8.143 ± 0.793

5.857 ± 2.744

< 0.001

2:1 chronic ( n  = 10)

 MIDAS

97.900 ± 73.847

52.500 ± 69.728

0.015

 HIT-6

66.200 ± 6.844

54.700 ± 20.106

0.022

 Migraine days/month

22.100 ± 8.386

8.800 ± 6.697

0.013

 Migraine Intensity (NRS)

8.500 ± 0.707

6.000 ± 2.449

0.002

2:1 episodic ( n  = 11)

 MIDAS

44.182 ± 21.531

12.455 ± 13.995

0.005

 HIT-6

66.727 ± 5.042

50.909 ± 12.169

0.004

 Migraine days/month

10.182 ± 1.601

4.364 ± 4.007

0.022

 Migraine Intensity (NRS)

7.818 ± 0.751

5.727 ± 3.101

0.002