Table 3 Incidence rates and hazard ratios for ischemic heart disease among migraine and control groups

Migraine and control group (n = 226,230)

 Migraine

2,973 / 45,246 (6.6)

416,160

7.14

1.69 (1.43 to 1.95)

1.31 (1.26–1.37)

< 0.001^*

1.31 (1.26–1.35)

< 0.001^*

 Control

9,012 / 180,984 (5.0)

1,651,691

5.46

1

1

Migraine with aura and control group (n = 16,815)

 Migraine with aura

227 / 3,363 (6.7)

33,886

6.70

2.05 (1.21 to 2.90)

1.44 (1.24–1.68)

< 0.001^*

1.21 (1.11–1.31)

< 0.001^*

 Control

624 / 13,452 (4.6)

134,352

4.64

1

1

Migraine without aura and control group (n = 209,414)

 Migraine without aura

2,746 / 41,883 (6.6)

382,261

7.18

1.66 (1.38 to 1.93)

1.30 (1.25–1.36)

< 0.001^*

1.27 (1.22–1.31)

< 0.001^*

 Control

8,388 / 167,532 (5.0)

1,517,339

5.53

1

1