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Table 2 Effect of estrus cycle stage on opto-SD induced periorbital mechanical thresholds

From: The effect of sex and estrus cycle stage on optogenetic spreading depression induced migraine-like pain phenotypes

Independent variables

Beta

95% CI

STE

|t|

p

Opto-SD

-26.24

-32.51

-19.96

3.13

8.38

 < 0.0001

Estrus cycle (PE or MD)

8.94

1.85

16.03

3.54

2.53

0.015

Single or Repeated stimulation

0.42

-4.54

5.39

2.47

0.17

0.865

Estrus cycle x Opto-SD

-4.58

-14.61

5.45

5.00

0.91

0.364

  1. Periorbital allodynia = β0 + β1(opto-SD) + β2(Estrus cycle) + β3(Single or Repeated stimulation) + β4(Estrus cycle x opto-SD)