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Table 2 Whiter matter with decreased FA, increased MD and RD (P FWE < 0.05)

From: Micro-structural white matter abnormalities in new daily persistent headache: a DTI study using TBSS analysis

Cluster size (Voxels)

MNI center of mass

Side

Brain region

Related function

X

Y

Z

2194

-28

45

1

L

IFOF

Language, emotion

1189

-25

-72

18

/

Forceps major

Emotion, pain processing

734

9

-51

7

R

Cingulum

Motivation, pain and emotion interactions

440

47

-53

26

R

SLF

Cognition, emotion

422

43

-9

-27

R

ILF

Language, visual memory, emotion

414

-12

-46

26

L

Cingulum

Motivation, emotion, pain perception

393

-6

15

20

/

BCC

Pain processing, emotion, cognition

389

-41

-11

-18

L

ILF

Language, visual memory, emotion

384

-23

-32

-15

L

CGH

Emotion, cognition

248

33

-15

-11

/

Fornix

Memory, emotion

229

-34

1

-13

L

UF

Emotion, cognition, language

148

10

-8

-12

R

ATR

Emotion

145

18

-40

31

/

SCC

Pain processing, emotion, cognition

135

28

-21

1

R

RPIC

Visual sense

124

-16

-23

-8

L

CST

Motor

113

-18

-7

8

L

PLIC

Pain processing

  1. Note: MNI Montreal Neurological Institute, L left, R right, IFOF inferior fronto-occipital fasciculus, SLF superior longitudinal fasciculus, ILF inferior longitudinal fasciculus, BCC body of corpus callosum, CGH hippocampal cingulum, UF uncinate fasciculus, ATR anterior thalamic radiation, SCC splenium of corpus callosum, RPIC retrolenticular part of internal capsule, CST corticospinal tract, PLIC posterior limb of internal capsule