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Table 3 Statistical comparisons, between patients with episodic migraine (EM) and healthy controls (HC), of anthropometric, clinical, and psychiatric variables, for Experiments 1 and 2

From: Exploring sensory sensitivity, cortical excitability, and habituation in episodic migraine, as a function of age and disease severity, using the pattern-reversal task

 

Experiment 1

Experiment 2

Variable

HC

EM

p

HC

EM

p

N

27

18

 

29

19

 

Gender (% of females)

100.0

100.0

 

82.8

84.2

1.00

Age (years old)

21.8 ± 2.03

22.8 ± 1.89

0.10

39.2 ± 8.84

40.9 ± 8.68

0.53

STAI-State (score)

12.2 ± 6.20

11.1 ± 5.90

0.53

5.0 [7.50]

11.0 [6.00]

0.002*

STAI-Trait (score)

20.4 ± 6.73

21.1 ± 7.96

0.76

12.0 [7.00]

19.0 [7.50]

0.001*

BDI-II (score)

2.0 [5.00]

3.0 [3.00]

0.90

2.0 [6.00]

6.0 [4.50]

0.003*

ASRS (score)

1.0 [3.00]

1.0 [2.00]

0.79

1.0 [2.00]

1.0 [2.00]

0.80

Migraine frequency (headache days/month)

NA

5.1 ± 3.24

 

NA

12.7 ± 4.03

 

MIDAS (score)

NA

7.0 [8.75]

 

NA

52.3 ± 27.89

 

HIT-6 (score)

NA

54.1 ± 5.99

 

NA

62.1 ± 5.67

 

MSQ (score)

NA

30.4 [11.60]

 

NA

53.0 ± 14.13

 

Accompanying symptoms of headache (% of participants)

  

   Aura

NA

31.6

 

NA

26.3

 

   Subjective presence of photophobia

NA

52.6

 

NA

  

   Subjective presence of phonophobia

NA

52.6

 

NA

  

   Nausea/vomiting

NA

31.6

 

NA

  

SPQ Total (score)

116.1 ± 18.3

108.9 ± 17.0

0.20

110.3 ± 23.2

106.5 ± 23.3

0.58

SPQ Vision (score)

31.4 ± 5.08

27.4 ± 4.36

0.01*

30.5 ± 4.96

26.2 ± 4.05

0.003*

SPQ Motion (score)

7.7 ± 1.80

7.2 ± 1.99

0.46

7.0 [1.00]

7.0 [2.50]

0.36

SPQ Brightness (score)

6.0 ± 1.74

4.6 ± 1.77

0.02*

5.0 [2.00]

4.0 [3.00]

0.01*

SPQ Color (score)

6.0 [1.50]

5.0 [3.00]

0.03*

5.0 [2.00]

5.0 [1.00]

0.19

SPQ Acuity (score)

21.0 ± 2.92

10.0 [2.00]

0.09

12.0 [3.00]

10.0 [2.50]

0.01*

  1. Means and standard deviations (mean ± SD) were used to report continuous normally distributed variables whereas medians and interquartile ranges (median [IQR]) were used for not normally distributed variables. To assess the null hypotheses, two-sided, unpaired t-tests of equal variance and two-sided, non-parametric Mann–Whitney U tests were used, respectively. Bold values with* were used to indicate significant differences between groups