Fig. 1
From: Neuroimaging in the pre-ictal or premonitory phase of migraine: a narrative review
Brain regions involved in mediating PS and the proposed interaction between monoaminergic (stars) and peptidergic (ovals) pathways between these areas. DA; dopamine, NA; noradrenaline, 5HT; serotonin, CGRP; calcitonin gene-related peptide, PACAP; pituitary adenylate cyclase activating polypeptide; RVM; rostroventral medulla, NRM; nucleus raphe magnus, TCC; trigeminocervical complex, SSN; superior salivatory nucleus, LC; locus coeruleus, CAS; cranial autonomic symptoms, PAG; periacqueductal gray, VTA; ventral tegmental area. Free to use sagittal brain image https://upload.wikimedia.org/wikipedia/commons/a/a0/Brain_human_sagittal_section.svgby, Patrick J. Lynch, medical illustrator, CC BY 2.5 https://creativecommons.org/licenses/by/2.5, via Wikimedia Commons. The authors have annotated the figure for the purpose of this article