Table 2 Potential therapeutic agents against Notch
From: Notch signaling pathway: a new target for neuropathic pain therapy
Therapeutics | Disease | Target | Reference |
|---|---|---|---|
Venetoclax | breast cancer | γ-secretase | [110] |
Ciclopirox (CPX) | Bladder cancer | [111] | |
Cucurbitacin B and I | Colorectal cancer (CRC) | [112] | |
RO4929097 | Advanced Sarcoma | [113] | |
BMS-906024 | Lung cancer | [114] | |
dibenzazepine (DBZ) | Obesity | [115] | |
Crenigacestat (LY3039478) | Calcific aortic valve disease (CAVD) | [116] | |
T-cell acute lymphoblastic leukemia (T-ALL)/T-cell lymphoblastic lymphoma (T-LBL) | [117] |