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Fig. 6 | The Journal of Headache and Pain

Fig. 6

From: Inhibition of glutamatergic trigeminal nucleus caudalis- vestibular nucleus projection neurons attenuates vestibular dysfunction in the chronic-NTG model of migraine

Fig. 6

Pharmacogenetic suppression of TNC-VN circuit attenuated mechanical allodynia, thermal hyperalgesia and vestibular dysfunction in chronic-NTG treated rats. Post-treatment responses of periorbital (A) and hind paw (B) mechanical, and thermal (C) thresholds among three groups. Balance beam walk (D) and negative geotaxis test (E) among three groups. N = 6 rats/group, each dot represents the average data of one rat. Two-way ANOVA with the Bonferroni post hoc test, *p < 0.05 compared with chronic-NTG + CNO group, **p < 0.005 compared with chronic-NTG + CNO group, ***p < 0.001 compared with chronic-NTG + CNO group

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