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Fig. 8 | The Journal of Headache and Pain

Fig. 8

From: SS-31 alleviated nociceptive responses and restored mitochondrial function in a headache mouse model via Sirt3/Pgc-1α positive feedback loop

Fig. 8

No interaction of Sirt3 and Pgc-1α complexes was detected in PC12 cells. Wild-type PC12 cells were cultured for western blot analysis and immunofluorescence staining, while PC12 cells infected by LV-Sirt3 were cultured for co-IP analysis. A Western blot analysis of Sirt3 and Pgc-1α to evaluate sub-cellular localization. B Co-IP analysis of Sirt3 and Pgc-1α. C Immunofluorescence staining of Sirt3, Pgc-1α and VDAC1. Scale bar, 10 μm. Cyt-: cytoplasm; Mit-: mitochondria

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The Journal of Headache and Pain

ISSN: 1129-2377

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