Table 1 Baseline demographic and clinical characteristics
|  | Placebo + saline + saline n = 5 | Placebo + PACAP38 + VIP n = 10 | Lu AG09222 + PACAP38 + VIP n = 10 | Overall n = 25 |
|---|---|---|---|---|
Age, years, mean (SD) | 30 (8.5) | 26 (7.6) | 27 (8.0) | 27 (7.7) |
Sex, n (%) | ||||
 Male | 2 (40) | 4 (40) | 4 (40) | 10 (40) |
 Female | 3 (60) | 6 (60) | 6 (60) | 15 (60) |
Race, n (%) | ||||
 Asian | 1 (20) | 1 (10) | 1 (10) | 3 (12) |
 White | 4 (80) | 6 (60) | 8 (80) | 18 (72) |
 Other | 0 | 3 (30) | 1 (10) | 4 (16) |
Body mass index, kg/m2, mean (SD) | 22.0 (3.75) | 22.3 (2.50) | 23.5 (3.44) | 22.7 (3.09) |
Superficial temporal artery diameter, mm, mean (SD) | ||||
 Visit 1 | 1.12 (0.165) | 1.02 (0.174) | 1.08 (0.229) | 1.06 (0.192) |
 Visit 2 | 1.04 (0.284) | 0.92 (0.128) | 1.07 (0.217) | 1.00 (0.205) |
Radial artery diameter, mm, mean (SD) | ||||
 Visit 1 | 2.34 (0.464) | 2.12 (0.340) | 2.41 (0.470) | 2.28 (0.425) |
 Visit 2 | 2.31 (0.381) | 2.10 (0.288) | 2.34 (0.398) | 2.24 (0.358) |
Facial blood flow, flux, mean (SD) | ||||
 Visit 1 | 539 (52.7) | 570 (111) | 527 (155) | 547 (120) |
 Visit 2 | 509 (95.7) | 519 (104) | 587 (153) | 544 (125) |
Heart rate, bpm, mean (SD) | ||||
 Visit 1 | 58.6 (4.16) | 64.0 (11.6) | 59.8 (8.78) | 61.2 (9.38) |
 Visit 2 | 59.0 (8.63) | 57.4 (8.53) | 59.3 (9.56) | 58.5 (8.65) |