Table 3 Mean change from baseline by route of administration

Placebo Route

Mean (SD) Change from Baseline for Continuous Outcomes

P-value

Oral (n = 35)

1.5 (1.5)

Injection (n = 33)

2.2 (1.5)

 < 0.001

Intravenous (n = 5)

4.7 (1.2)

Placebo Route

Mean (SD) Change from Baseline for Dichotomous Outcomes

P-value

Oral (n = 23)

26.7% (15.9)

Injection (n = 21)

24.5% (14.0)

0.011

Intravenous (n = 6)

45.1% (7.8)