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Fig. 4 | The Journal of Headache and Pain

Fig. 4

From: Neuroanatomical restoration of salience network links reduced headache impact to cognitive function improvement in mild traumatic brain injury with posttraumatic headache

Fig. 4

Relationships between the neuroanatomical restoration of hub nodes in salience network, reduced traumatic-induced headache impact and cognitive function improvement in patients. A Cognitive function improvement was significantly correlated with restoration of left insula, left ACC, and reduced headache impact; the reduced headache impact was significantly correlated with restoration of left insula, and left ACC. Black numbers represent positive effects. Both the restoration of B left insula and C left ACC mediated the relationship between reduced headache impact and cognitive function improvement, respectively. MTBI, mild traumatic brain injury; PTH, posttraumatic headache; ACC, anterior cingulate cortex; SFG, superior frontal gyrus; 95% CI, 95% confidence interval; *, P < 0.05;.**, P < 0.01

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