Fig. 4From: Neuroanatomical restoration of salience network links reduced headache impact to cognitive function improvement in mild traumatic brain injury with posttraumatic headacheRelationships between the neuroanatomical restoration of hub nodes in salience network, reduced traumatic-induced headache impact and cognitive function improvement in patients. A Cognitive function improvement was significantly correlated with restoration of left insula, left ACC, and reduced headache impact; the reduced headache impact was significantly correlated with restoration of left insula, and left ACC. Black numbers represent positive effects. Both the restoration of B left insula and C left ACC mediated the relationship between reduced headache impact and cognitive function improvement, respectively. MTBI, mild traumatic brain injury; PTH, posttraumatic headache; ACC, anterior cingulate cortex; SFG, superior frontal gyrus; 95% CI, 95% confidence interval; *, P < 0.05;.**, P < 0.01Back to article page