Table 2 Differences in circulating cytokines levels between patients with migraine and healthy controls
From: Cytokines in primary headache disorders: a systematic review and meta-analysis
Cytokine | N of studies | Total participants | Std. Mean Difference (95% CI) Effect Estimate | P Value | I2 |
|---|---|---|---|---|---|
IL-1β | 7 | 502 | 0.50 (-0.54, 1.54) | 0.34 | 96% |
IL-2 | 6 | 348 | 0.58 (-0.37, 1.54) | 0.23 | 92% |
IL-4 | 5 | 346 | 0.88 (-1.65, 3.41) | 0.49 | 98% |
IL-6 | 16 | 264 | 1.07 (0.40, 1.73) | 0.002 | 96% |
IL-8 | 6 | 163 | 1.56 (0.03, 3.09) | 0.04 | 95% |
IL-10 | 12 | 706 | 0.10 (-0.74, 0.94) | 0.41 | 95% |
TGF-β | 2 | 219 | 2.05 (-0.29, 4.40) | 0.09 | 98% |
TNF-α | 14 | 914 | 0.61 (0.14, 1.09) | 0.01 | 90% |
IFN-γ | 6 | 301 | 1.23 (-0.03, 2.49) | 0.06 | 93% |