Fig. 2
From: MARS1 mutations linked to familial trigeminal neuralgia via the integrated stress response
Sanger sequence MARS1 in Family 1 and nonfamilial TN subject group. a We performed Sanger sequencing to confirm the MARS1 mutation and found that its presence was widespread in Family 1. Roman numerals denote generations. Numbers 1–3 are probands in Family 1. Numbers 3–9 are subjects in the FTN family member group in Family 1. The MARS1 mutation is identified in numbers 3–6. Numbers 6–9 are negative. b We performed Sanger sequencing to confirm the MARS1 mutation (c.2398C > A) in nonfamilial TN subject group. Three subjects did not have MARS1 mutation. All the probands and subjects in Fig. 2 were subjected to RNA-seq