Fig. 1 (abstract A21).
From: 16th European Headache Congress 2022 meeting abstracts
Manhattan plots from the epigenome-wide association study. Manhattan plot showing the -log10 p value for each CpG site. The threshold for genome wide significance (p <9.42 x 10-1) is indicated by a continues line. The threshold for suggestive genome wide significance (p < 5 x 10-1) is indicated by a striped line. Changes in DNA methylation in monthly headache days (MHD) responders vs non-responders (A): changes in DNA methylation in monthly migraine days (MMD) responders vs non-responders (B). Predictive value of DNA methylation profiles at baseline of favourable treatment response for MHD (C) and MMD (D)