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Table 4 Changes in headache frequency, migraine frequency, and ASC-12 scores. Change in headache and migraine frequency compares weeks 5–8 after the first erenumab treatment to the 4-week pre-treatment period. Change in ASC-12 scores compares those obtained during the research visit at 8 weeks after the first erenumab treatment to those collected just before the first treatment. ASC-12 = Allodynia Symptom Checklist 12

From: Longitudinal changes in functional connectivity and pain-induced brain activations in patients with migraine: a functional MRI study pre- and post- treatment with Erenumab

 

All Participants (n = 32)

Responders (n = 18)

Non-Responders (n = 14)

p-value (responders vs. non-responders)

Change in Headache Day Frequency/ 28 days, mean

− 7.1

−10.1

− 3.4

< 0.001

Change in Migraine Day Frequency/ 28 days, mean

− 6.9

− 10.3

−2.4

< 0.001

Change in ASC-12 scores, mean

− 1.6

−3.4

0.8

< 0.001