Fig. 3

Pain-induced BOLD activations measured immediately after onset of painful stimuli, comparing erenumab-responders to non-responders. The “immediate” BOLD activations were measured starting with the MRI frame during which the painful heat stimulus began and ending 12.5 s later. The group-visit effect with p < 0.005 with voxel forming threshold above 50 is shown for 3 regions. The longitudinal contrast averages in these regions are shown with error bars representing standard error. Mid = middle