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Table 2 Comparisons of demographics and clinical characteristics between CM with and without MOH

From: Altered functional connectivity of the right caudate nucleus in chronic migraine: a resting-state fMRI study

 

Without MOH

(N = 22)

With MOH

(N = 24)

P value

Gender (female/male)

6 / 22

7 / 24

0.915a

Age (years)

36.77 ± 16.06

40.67 ± 9.33

0.660b

BMI (kg/m2)

22.65 ± 2.94

22.99 ± 4.09

0.974b

Migraine history (years)

13.50 ± 11.76

21.54 ± 11.46

0.021b

CM history (months)

16.73 ± 19.22

59.75 ± 59.96

< 0.001b

Headache frequency (d/mo)

22.00 ± 6.67

26.04 ± 5.31

0.033b

Pain intensity VAS score

6.68 ± 1.67

7.21 ± 1.28

0.306b

MIDAS score

136.41 ± 61.81

115.88 ± 71.02

0.303c

HIT-6 score

65.68 ± 6.67

66.17 ± 8.98

0.559b

PHQ-9 score

11.95 ± 5.74

9.71 ± 6.59

0.226c

GAD-7 score

9.05 ± 5.58

6.96 ± 5.72

0.222c

PSQI score

10.14 ± 5.15

9.74 ± 4.60

0.786c

  1. Note: MOH, medication overuse headache; BMI, Body Mass Index; CM, chronic migraine; d/mo, days per month; MIDAS, Migraine Disability Assessment Scale; HIT-6, Headache Impact Test-6; PHQ-9, Patient Health Questionnaire-9; GAD-7, Generalized Anxiety Disorder-7; PSQI. Pittsburgh   Sleep Quality Index; VAS, Visual Analogue Scale.
  2. Values represent mean ± SD or n (% of total)
  3. a Chi-square test
  4. b Mann-Whitney U test
  5. c Independent samples t test