Fig. 3

Differences in the FC values of the right CN between the CM, EM, and HC groups. (A). Right CN masks generated based on the automated anatomical labeling atlas. (B). When using the right CN as the seed, patients with CM show significantly higher FC values than HCs. (C). Patients with CM show significantly higher FC of the right CN than patients with EM. FC values in the (D).emotion-cognition related and (E). sensory-related brain regions show significant differences in HCs and patients with CM. (F). Patients with CM show significant FC values differences between the right CN and certain brain regions than EM patients. The color bar shows the t-values of the two-sample t-tests on FC.

Note: L, left; R, right; FC, functional connectivity; CN, caudate nucleus; CM, chronic migraine; EM, episodic migraine; HC, healthy control.