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Fig. 1 | The Journal of Headache and Pain

Fig. 1

From: Predictors of response to anti-CGRP monoclonal antibodies: a 24-week, multicenter, prospective study on 864 migraine patients

Fig. 1

A In patients with HFEM, unilateral pain (UP) associated with unilateral cranial autonomic symptoms (UAs) – clinical manifestation of CGRP-mediated peripheral sensitization - predict both ≥ 50 and ≥ 75% response to antiCGRP mAbs. B In patients with CM, UAs and UP + UAs predict ≥ 50 response to antiCGRP mAbs, while UP + UAs and UP associated with allodynia - a CGRP-mediated symptom of central sensitization - predict ≥ 75% response

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The Journal of Headache and Pain

ISSN: 1129-2377

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