Functional connectivity and structural changes of thalamic subregions in episodic migraine

Table 5 Partial correlations between decreased rsFC and clinical data in patients with episodic migraine after controlling for age, sex, education, and FD

	Disease duration (years)	VAS	HIT-6	HAMA	BDI-II	MoCA
Decreased rsFC between *L-rTtha* and *L-Precuneus*
*P(r)*	-0.235	-0.182	-0.145	-0.301	0.173	0.131
P value	0.293	0.418	0.554	0.045*	0.319	0.593
Decreased rsFC between *L-PPtha* and *L-ACC-sup*
*P(r)*	-0.009	0.074	0.147	-0.389	-0.169	0.125
P value	0.967	0.742	0.547	0.008*	0.333	0.609
Decreased rsFC between *L-Otha* and *L-Frontal-sup-medial*
*P(r)*	-0.156	-0.065	0.110	-0.286	0.056	0.144
P value	0.489	0.774	0.655	0.057	0.748	0.556
Decreased rsFC between *R-Otha* and *L-Frontal-sup-medial*
*P(r)*	-0.006	-0.235	-0.177	-0.283	-0.040	0.378
P value	0.980	0.293	0.468	0.060	0.818	0.111
Decreased rsFC between *R-Otha* and *L-Cingulate-post*
*P(r)*	-0.042	-0.383	-0.358	-0.338	0.060	0.088
P value	0.851	0.079	0.132	0.023*	0.733	0.721
Decreased rsFC between *L-cTtha* and *L-Frontal-sup*
*P(r)*	0.073	-0.078	0.301	-0.354	0.022	0.372
P value	0.745	0.730	0.210	0.017*	0.898	0.117
Decreased rsFC between *L-cTtha* and *R-ACC-pre*
*P(r)*	-0.075	0.003	0.012	-0.303	-0.095	0.276
P value	0.741	0.990	0.961	0.043*	0.586	0.253
Decreased rsFC between *L-cTtha* and *L-Precuneus*
*P(r)*	-0.040	-0.248	-0.069	-0.357	0.047	0.131
P value	0.860	0.266	0.780	0.016*	0.787	0.594

Abbreviations: rTtha Rostral temporal thalamus, PPtha Posterior parietal thalamus, Otha Occipital thalamus, cTtha Caudal temporal thalamus, ACC-sup Anterior cingulate cortex, supracallosal, Frontal-sup-medial Superior frontal gyrus, medial, Cingulate-post Posterior cingulate gyrus, Frontal-sup Superior frontal gyrus, dorsolateral, ACC-pre Anterior cingulate cortex, pregenual, FD framewise displacement, VAS Visual Analogue Scale, HIT-6 Headache Impact Test, HAMA Hamilton Rating Scale for Anxiety, BDI-II Beck Depression Inventory-II, MoCA Montreal Cognitive Assessment, rsFC Resting-state functional connectivity, L Left, R right
^*P < 0.05

ISSN: 1129-2377