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Fig. 1 | The Journal of Headache and Pain

Fig. 1

From: Dopamine receptor D2 regulates GLUA1-containing AMPA receptor trafficking and central sensitization through the PI3K signaling pathway in a male rat model of chronic migraine

Fig. 1

Lower pain thresholds in the CM group. A and B The hind paw mechanical and thermal pain thresholds in rats treated with IS injection were markedly lower than those in rats treated with PBS. C The periorbital pain threshold was markedly decreased in the CM group compared to the Sham group. Two-way ANOVA with Bonferroni post hoc test; n = 6/group; *P < 0.05, **P < 0 .01, ***P < 0.001 vs. the Sham group

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The Journal of Headache and Pain

ISSN: 1129-2377

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